Results 211 to 220 of about 199,847 (309)

Association of HAMP Expression and CD8+ T‐Cell Infiltration With Atezolizumab–Bevacizumab Response in Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
In hepatocellular carcinoma treated with atezolizumab–bevacizumab, responders showed RNA‐seq enrichment of immune and chemokine pathways with higher HAMP expression. In resected specimens, immunohistochemistry confirmed increased intratumoral CD8+ T‐cell density and hepcidin (HAMP), supporting HAMP plus CD8 as components of a composite predictor of ...
Shun Nakamura, Yuki Murakami, Yusuke Oshima, Takashi Masuda, Wataru Miyoshino, Hiroomi Takayama, Yoko Kawano, Teijiro Hirashita, Yuichi Endo, Masafumi Inomata   +9 more
wiley   +1 more source

Synchronous activation of striatal cholinergic interneurons induces local serotonin release. [PDF]

Nat Commun
Matityahu L, Hobel ZB, Berkowitz N, Malgady JM, Gilin N, Plotkin JL, Goldberg JA.   +6 more
europepmc   +1 more source

Independent Prognostic Significance of Perforation in Colorectal Cancer: Insights From a Propensity Score‐Matched Cohort Study

Annals of Gastroenterological Surgery, EarlyView.
Perforated colorectal cancer (PCC) is considered to have a poor prognosis; however, it remains unclear whether this is attributable to perforation itself or to perforation‐related clinicopathological factors. In this study, we analyzed prognosis using propensity score matching with perforation‐related factors and demonstrated that perforation is an ...
Yoshiaki Fujii, Shuhei Ueno, Yoshinaga Aoyama, Hiroyuki Imafuji, Takahisa Hirokawa, Hirotaka Miyai, Masahiro Kimura, Kenji Kobayashi, Shuji Takiguchi   +8 more
wiley   +1 more source

Altered Habenula Resting-State Functional Connectivity and Spatial Associations with Neurotransmitter Receptor Distribution of Major Depressive Disorder with and without Anhedonia. [PDF]

Neuropsychiatr Dis Treat
Luo X, Wu Y, Yuan L, Wang Y, Li J, Xu P, Lian J, Liu X, Shen Z.   +8 more
europepmc   +1 more source

Survival Outcomes of Gemcitabine–Cisplatin–S‐1 Versus Gemcitabine–Cisplatin in Unresectable Biliary Tract Cancer: A Multicenter Retrospective Study With a Focus on Conversion Surgery

Annals of Gastroenterological Surgery, EarlyView.
In this multicenter retrospective study conducted by the Biliary Tract Club, we compared survival outcomes between gemcitabine–cisplatin–S‐1 (GCS) and gemcitabine–cisplatin (GC) in patients with unresectable biliary tract cancer, with a particular focus on conversion surgery. GCS was associated with longer overall and progression‐free survival compared
Hisashi Kosaka, Masahiko Kinoshita, Satoshi Yasuda, Satoru Kakizaki, Rie Sugimoto, Jun Sakata, Kiyonori Yamai, Takeshi Hatanaka, Yusuke Yamamoto, Toshifumi Sato, Toru Ishikawa, Takanori Morikawa, Jun Hanaoka, Haruki Mori, Hidenori Toyoda, Tsuyoshi Sanuki, Misaki Yokoi, Hiroyuki Shibata, Koji Fukuda, Kazuhito Kawata, Koji Amaya, Takashi Ito, Masaaki Hidaka, Atsushi Naganuma, Keishi Sugimachi, Satoshi Toshiyama, Makoto Yamasaki, Masaki Kaibori   +27 more
wiley   +1 more source

Brain-gut-microbiota axis: a review on the bidirectional regulatory mechanisms between gut microbiota and brain and their disease interactions. [PDF]

Front Microbiol
Shen H, Wang SY, Zhao YY, Zhou JL, Zhao J, Zhu WK.   +5 more
europepmc   +1 more source

Monitoring and control of a continuous, integrated filtration‐drying system with in‐line mass spectrometry via PharmaPy

AIChE Journal, EarlyView.
Abstract This article demonstrates the integration of in‐line mass spectrometry as a process analytical technology (PAT) tool with model‐based soft sensors in a continuous filtration‐drying carousel system for solid–liquid separation (SLS) of crystal slurries.
Inyoung Hur, Daniel Casas‐Orozco, Gintaras Reklaitis, Zoltan K. Nagy   +3 more
wiley   +1 more source

Chronic constipation and the brain-gut-microbiome axis: the role of 5-HT signaling and Traditional Chinese Medicine in pathophysiology and treatment. [PDF]

Front Med (Lausanne)
Zhang S, Song X, Wen Y, Wang G.
europepmc   +1 more source

Erosion of granular sediments by submerged impinging jets: Particle size effects and cohesion onset

AIChE Journal, EarlyView.
Abstract This study investigates the erosion behavior and modeling of glass particle beds under impinging jet conditions, with a focus on particle size effects and the onset of cohesion. Ultrasonic profiling is implemented to scan and measure static crater profiles.
Ahmad Mohamadiyeh, Jeffrey Peakall, Michael Fairweather, Martyn Barnes, Timothy N. Hunter   +4 more
wiley   +1 more source

I've got a friend somewhere: control of social behavior across striatal subregions. [PDF]

Front Behav Neurosci
Li MX, Baek J, Guo MY, Pomrenze MB, Chen APF.   +4 more
europepmc   +1 more source