Results 31 to 40 of about 7,469 (209)

Kynurenine pathway in post-mortem prefrontal cortex and cerebellum in schizophrenia: relationship with monoamines and symptomatology

Journal of Neuroinflammation, 2021
Background The cortico-cerebellar-thalamic-cortical circuit has been implicated in the emergence of psychotic symptoms in schizophrenia (SZ). The kynurenine pathway (KP) has been linked to alterations in glutamatergic and monoaminergic neurotransmission ...
Amira Ben Afia, Èlia Vila, Karina S. MacDowell, Aida Ormazabal, Juan C. Leza, Josep M. Haro, Rafael Artuch, Belén Ramos, Borja Garcia-Bueno   +8 more
doaj   +1 more source

Assessment of Serotonin Metabolite 5-hydroxyindoleacetic Acid Levels in Urine Sample for Diagnosis and Treatment Efficacy in Children with Dysfunctional Voiding and Their Interaction with Biofeedback Therapy

Journal of Urological Surgery, 2018
Objective:Dysfunctional voiding (DV), which is explained as an incoordination between the external urethral sphincter and the bladder, is a situation developing in neurologically normal children.
Bahadır Topuz, Giray Ergin, Burak Köprü, Turgay Ebiloğlu, Hasan Cem Irkılata, Yusuf Kibar, Musa Murat Dayanç   +6 more
doaj   +1 more source

Autoimmune Pancreatitis Associated with High Levels of Chromogranin A, Serotonin and 5-Hydroxyindoleacetic Acid

Case Reports in Gastroenterology, 2008
We report a case of a male patient with autoimmune pancreatitis in whom biochemical examination revealed high plasma chromogranin A concentrations, histological demonstration of a small lymphocytic infiltrate and rapid decrease in size of the pancreatic ...
Elisabetta Nobili, Raffaele Pezzilli, Donatella Santini, Cristina Campidelli, Lucia Calculli, Riccardo Casadei, Guido Biasco   +6 more
doaj   +1 more source

Depressive disorder and gastrointestinal dysfunction after myocardial infarct are associated with abnormal tryptophan-5-hydroxytryptamine metabolism in rats. [PDF]

PLoS ONE, 2017
In this study, we investigated the relationship between tryptophan-5-hydroxytryptamine metabolism, depressive disorder, and gastrointestinal dysfunction in rats after myocardial infarction.
Xiaofang Lu, Yuefen Wang, Chunyan Liu, Yangang Wang   +3 more
doaj   +1 more source

Tryptophan in banana peel (Musa paradisiaca) as an anti-dementia alternative treatment: A narrative review

JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2021
As the prevalence of dementia increases from year to year, the discovery and invention of preventive measures are growing increasingly urgent. Banana peels contain tryptophan, an amino acid that plays a substantial role in the mechanism of dementia ...
Daffara Kinanthi Lustikaiswi, Sapto Yuliani, Rahmah Annura, Elmi Rahmadani   +3 more
doaj   +1 more source

Neurotransmitter evaluation in the hippocampus of rats after intracerebral injection of TsTX scorpion toxin

Journal of Venomous Animals and Toxins including Tropical Diseases, 2009
TsTX is an α-type sodium channel toxin that stimulates the discharge of neurotransmitters from neurons. In the present study we investigated which neurotransmitters are released in the hippocampus after TsTX injection and if they are responsible for
ALA Nencioni, SA Barreto, I Lebrun, JC Florio, GA Lourenço, VAC Dorce   +5 more
doaj   +1 more source

Progression of Carcinoid Heart Disease in the Modern Management Era

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background The development of carcinoid heart disease (CaHD) is still relatively unclear. It is difficult to define an optimal follow‐up for patients without any cardiac involvement at baseline.
Emilie Baron, Catherine Szymanski, Hélène Hergault, Céline Lepère, Olivier Dubourg, Marie Hauguel‐Moreau, Nicolas Mansencal   +6 more
doaj   +1 more source

Developmental exposure to fluoxetine modulates the serotonin system in hypothalamus. [PDF]

PLoS ONE, 2013
The selective serotonin reuptake inhibitor (SSRI) fluoxetine (FLU, Prozac®) is commonly prescribed for depression in pregnant women. This results in SSRI exposure of the developing fetus.
Cecilia Berg, Tobias Backström, Svante Winberg, Richard Lindberg, Ingvar Brandt   +4 more
doaj   +1 more source

Metabolites of Tryptophane and Phenylalanine as Markers of Small Bowel Ischemia-Reperfusion Injury

Open Chemistry, 2018
Ischemic-reperfusion injury of the small intestine is an acute clinical condition with high mortality rate. This study describes the changes in levels of phenylalanine and tryptophan metabolites in intestinal homogenates and urine samples of Wistar male ...
Mašlanková Jana, Tóth Štefan, Tomečková Vladimíra, Tóth Tímea, Katz Matan, Veselá Jarmila, Hertelyová Zdenka, Schnitzer Marek, Živčák Jozef, Mareková Mária   +9 more
doaj   +1 more source

Valproic Acid-Induced Autistic-Like Behavior Is Accompanied by Intestinal Damage Driving Changes in Gut Permeability in a Sex-Dependent Way in Rats. [PDF]

J Neurochem
Exposure to valproic acid (VPA) caused sex‐dependent changes in the gut–brain axis, with more pronounced effects in males, including intestinal barrier dysfunction, blood–brain barrier (BBB) impairment, and social behavior deficits. Females showed intestinal inflammation and increased vascular permeability in the ileum, but no behavioral or intestinal ...
Longo B, Nunes RKS, Cazarin CA, Silva TFQE, Sievers J, Nilz ACDS, Venzon L, da Silva LM, Willrich CH, Cury BJ, Costa RA, de Souza MM, Stern CAJ, Zampronio AR, da Silva LM.   +14 more
europepmc   +2 more sources