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CORRIGENDUM: Correction Document for TET-Like Oxidation in 5-Methylcytosine and Derivatives: A Computational and Experimental Study. [PDF]
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5-Methylcytosine in Eukaryotic DNA
Science, 1981A small portion of the cytosine residues in the DNA of higher eukaryotes as well as in that of many lowe eukaryotes if methylated. The resulting 5-methylcytosine residues occur in specific in the DNA, usually adjacent to guanine residues on the 3' side.
M, Ehrlich, R Y, Wang
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5-Methylcytosine-Rich Heterochromatin in Reptiles
Cytogenetic and Genome Research, 2019An experimental approach using monoclonal anti-5-methylcytosine antibodies and indirect immunofluorescence was elaborated for detecting 5-methylcytosine-rich chromosome regions in reptilian chromosomes. This technique was applied to conventionally prepared mitotic metaphases of 2 turtle species and 12 squamate species from 8 families.
Michael Schmid +7 more
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5-Methylcytosine in Chlorella pyrenoidosa DNAs
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1976The presence of 5-methylcytosine in Chlorella pyrenoidosa (strain 211/8b) DNA's has been investigated by means of paper chromatography and thermal chromatography on hydroxyapatite. It has been shown that nuclear DNA contains 3.5 mol% 5-methylcytosine whereas no significant amount of this base can be detected in chloroplast DNA.
M, Bayen, J, Dalmon
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Phosphopeptides Designed for 5-Methylcytosine Recognition
Biochemistry, 2011An artificial phosphopeptide has been developed through rational design of the interaction with 5-methylcytosine in duplex DNA. The peptide consists of two tandem zinc finger motifs, in one of which the glutamate was replaced with a phosphotyrosine, the phosphotyrosine in the peptide being effective for methylcytosine selectivity of DNA binding.
Akiko, Nomura, Akimitsu, Okamoto
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Structure of 5-methylcytosine hydrochloride
Acta Crystallographica Section C Crystal Structure Communications, 1987$C_5H_8N_30^+.C1^ -$, $M_r= 161.6$, monoclinic, $P2_1/c$, a=6.431(1), b=16.132(2), c=7.030(1)A, \beta=97.33(1)°, $V=723.29\AA ^3, Z=4, D_x=1.48, D_ m = 1.49 Mg m^{-3}$, \lambda(Cu Ka) = 1.5418 \AA, \mu = 0.423 $mm^{-1}$, F(000) = 336, T = 295 K, R = 0.042 for 1146 observed reflections with I > 3\rho(I). The cytosine base is protonated at N(3).
Padmaja, N, Ramakumar, S, Viswamitra, MA
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5-methylcytosine formation in wheat embryo DNA
Biochemical and Biophysical Research Communications, 1980Summary The methylation of cytosine residues in wheat DNA was studied in isolated embryos during the first 30 hrs of germination. L-Methionine, but also L-serine serve as methyl group donors in vivo . DNA methylation reaches high values after the maximum of DNA replication at 18 hrs.
G, Theiss, H, Follmann
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FLUORESCENCE OF 5‐METHYLCYTOSINE
Photochemistry and Photobiology, 1970Abstract— 5‐Methylcytosine and 5‐methyldeoxycytidylic acid are fluorescent in aqueous solution at room temperature and neutral pH. 5‐Methylcytosine, 10‐3M, pH 8.5, 25°C, has a quantum yield of 5 ×10‐4, 5‐Methyldeoxycitydylic acid, 10‐4M, pH 7.5, 20°C, has a quantum yield of 8 × 10‐4. Emission maxima are 2.91 and 2.80μ‐1.
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5-Methylcytosine, Gene Regulation, and Cancer
1983Publisher Summary This chapter focuses on 5-methylcytosine, gene regulation, and cancer. The regulation of mammalian gene expression clearly is accomplished by multiple control systems operating at several levels. Some obvious levels of control include chromosome condensation, chromatin structure transcriptional control by repressors and activators ...
A D, Riggs, P A, Jones
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