Results 191 to 200 of about 20,996,854 (289)

Genome‐wide and gene‐specific DNA methylation across developmental stages in Pogonomyrmex californicus: A socially polymorphic ant

open access: yesInsect Molecular Biology, Volume 35, Issue 3, Page 232-245, June 2026.
Comparison between developmental stages (larvae, pupae, worker) in Pogonomyrmex californicus revealed significant stage‐specific differences in Gene Body Methylated frequencies. Methylation sites were highly correlated between WGBS and ONT in P. californicus Genome‐wide methylation was low (~3%) and highly clustered within gene bodies (GBM), especially
Tania Chavarria‐Pizarro   +4 more
wiley   +1 more source

HM-DyadCap - capture and mapping of 5-hydroxymethylcytosine/5-methylcytosine CpG dyads in mammalian DNA. [PDF]

open access: yesNucleic Acids Res
Engelhard L   +10 more
europepmc   +2 more sources

Resilient Biophysical Phenotype of Memory CD4 + T Cells in Long‐Lived Mice

open access: yesImmunology, Volume 178, Issue 2, Page 363-374, June 2026.
Aging is associated with increased stiffness and reduced migratory capacity of memory CD4+ T cells; however, these biophysical declines do not persist in exceptionally long‐lived mice. Instead, long‐lived individuals preserve T cell mechanics, migration and intracellular architecture, supporting mechanical resilience as a hallmark of successful immune ...
Aldo Abarca‐Ortega   +6 more
wiley   +1 more source

Salivary Microvesicle Methylome and Microbiome Profiles in Periodontitis: An Exploratory Study

open access: yesJournal of Clinical Periodontology, Volume 53, Issue 6, Page 911-923, June 2026.
ABSTRACT Aim Salivary microvesicles (MVs) are nanosized extracellular vesicles from the host and microbiota whose cargo may mirror the biological state of their parent cells. This cross‐sectional study aimed to explore the diagnostic power of host methylome and microbiome profiles of MVs in various periodontal disease states. Materials and Methods This
Pingping Han   +5 more
wiley   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

open access: yesJournal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1722-1742, June 2026.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin   +2 more
wiley   +1 more source

The aging paradox of Cushing's syndrome: Stress without clear senescence?

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 6, June 2026.
Abstract Cushing's syndrome (CS), characterized by chronic endogenous hypercortisolism and disruption of the normal circadian cortisol rhythm, represents a unique human model for investigating the interplay between stress endocrinology and biological aging.
Israel Nunes Silveira   +1 more
wiley   +1 more source

Advances in Visualizing Cytosine Methylation and Allele‐Specific Epigenetic States in Tissue Context

open access: yesPathology International, Volume 76, Issue 6, June 2026.
The ICON method enables sequence‐specific, bisulfite‐free visualization of DNA methylation through chemical recognition of methylated cytosines. Following probe hybridization under mild denaturing conditions, methylation‐dependent interstrand complexes are stabilized by covalent crosslinking.
Sohei Kitazawa   +2 more
wiley   +1 more source

Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution

open access: yesNature Biotechnology, 2019
Yibin Liu   +9 more
semanticscholar   +1 more source

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