Use of 5-Nitroimidazole drugs in the treatment of periodontitis
, 2014 Periodontal disease, a common cause of tooth loss, is an inflammatory response to the overgrowth of anaerobic and micro-aerophilic organisms in the subgingival plaque. Various 5-Nitroimidazole chemotherapeutic agents have been discussed in this review article with a special emphasis on periodontal gels because of their relatively fast rate of drug ...
Bansal Kailash, Sanjay Singh
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NITROIMIDAZOLES XI [I]. SYNTHESES OF DISUBSTITUTED NITROIMIDAZOLYLQUINOLINES [PDF]
Journal of Sciences, Islamic Republic of Iran, 1995 Reaction of substituted-aniline (8) with ethyl (l-methyl-5-nitroimidazole-2- carbonyl) acetate (9) gave 4-hydroxy-2-(l-methyl-5-nitro-2-imidazolyl)- substituted-quinolines (lo), which were converted to compound 11 with phosphorus oxychloride. Substituted-
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A new approach to study semi-coordination using two 2-methyl-5-nitroimidazole copper(ii) complexes of biological interest as a model system. [PDF]
RSC Adv, 2023 Fachini LG +7 more
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Reversion of heme-dependent metronidazole resistance in Clostridioides difficile
Microbiology SpectrumSince the emergence of epidemic Clostridioides difficile in the early 2000s, reduced susceptibility to metronidazole (MTZ), once a frontline antibiotic for treating C. difficile infection, has emerged.
Lillia Louis +3 more
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Synergistic Activity of Nitroimidazole-Oxazolidinone Conjugates against Anaerobic Bacteria
, 2020 The introductions of the bicyclic 4-nitroimidazole and the oxazolidinone classes of antimicrobial agents represented the most significant advancements in the infectious disease area during the past two decades.
Ding, Charles Z +27 more
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The determination of nitroimidazole residues in fish and fish products [PDF]
, 2011 xvii, 278 leaves : ill. ; 29 cm.Includes abstract.Includes bibliographical references (leaves 156-164).A method was developed and validated for the determination of nitroimidazoles (NIs) including 2-hydroxymethyl-1-methyl-5-nitroimidazole (HMMNI ...
Watson, Lynn
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, 1982 Treatment of l-methyl-2-methylsulphonyl-5-nitroimidazole(2) with p-hydroxybenzaldehyde gives the aldehyde (3a) which is derivatised further to 3b-d. Displacement reactions on 2 with other phenols affords 4a-c.
Shenoy, S. J. +3 more
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SYNTHESES, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF 2-ARYL-4- QUINOLINE- CARBOXAMIDE DERIVATIVES [PDF]
Journal of Sciences, Islamic Republic of Iran, 1993 Reaction of aryl methyl ketone with isatin in the presence of a base afforded 2- arylquinoline-4-carboxylic acid (3). Reaction of diazomethane with compound 3 yielded the ester 4. Compound 5 was prepared from the reaction of N, N'-dialkylethyl (or propyl)
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Some nitroimidazole derivatives as possible antibacterial agents
, 1993 PubMed: 8323675In this study, six 1-[2(benzazol-2-yl)thioethy-2-methyl-5-nitroimidazole derivatives were synthesized. Antibacterial activities of the compounds obtained were examined and it was found that they are effective against aerobe ...
Kiraz, N., Demirayak, Şeref
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Radiation Damage in Carnidazole: a Single Crystal EPR Study
CHIMIA, 1992 Single crystals of hydrated and anhydrous carnidazole have been subjected to X-irradiation at 77 K and studied by EPR. The determination of the EPR tensors shows that NO2, sulfur-centered radicals as well as a radical pair can be generated from ...
Théo Berclaz +3 more
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