Acta Crystallographica Section E: Crystallographic Communications, 2016 1,2-Dimethyl-5-nitroimidazole (dimetridazole, dimet) is a compound that belongs to a class of nitroimidazole drugs that are effective at inhibiting the activity of certain parasites and bacteria. However, there are few reports that describe structures of
Patrick J. Quinlivan, Rita K. Upmacis
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TDAE Strategy in the Benzoxazolone Series: Synthesis and Reactivity of a New Benzoxazolinonic Anion [PDF]
, 2015 International audienceWe describe an original pathway to produce new 5-substituted 3-methyl-6-nitro-benzoxazolones by the reaction of aromatic carbonyl and α-carbonyl ester derivatives with a benzoxazolinonic anion formed exclusively via the TDAE ...
Khoumeri, Omar +4 more
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NITROIMIDAZOLES XI [I]. SYNTHESES OF DISUBSTITUTED NITROIMIDAZOLYLQUINOLINES [PDF]
Journal of Sciences, Islamic Republic of Iran, 1995 Reaction of substituted-aniline (8) with ethyl (l-methyl-5-nitroimidazole-2- carbonyl) acetate (9) gave 4-hydroxy-2-(l-methyl-5-nitro-2-imidazolyl)- substituted-quinolines (lo), which were converted to compound 11 with phosphorus oxychloride. Substituted-
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A new approach to study semi-coordination using two 2-methyl-5-nitroimidazole copper(ii) complexes of biological interest as a model system. [PDF]
RSC Adv, 2023 Fachini LG +7 more
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Comparisons of halogenated ß-nitrostyrenes as antimicrobial agents [PDF]
The influence of three types of halogen-substituted E-ß-methyl-ß-nitrostyrenes (such as Compounds B, D, H) to overcome bacterial activity that is currently a significant health threat was studied.
Cornell, H +4 more
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Comparison anti-giardia activity of Satureja hortensis alcoholic extract and metronidazole in vitro [PDF]
, 2016 Background and aims: Giardiasis is known as intestinal infection and created by the flagellate protozoan Giardia lamblia. Some studies showed that phenolic components, present in plant extracts and essential oils, have anti-Giardia activity.
Abbasi Maleki, S., Davoodi, J.
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Reversion of heme-dependent metronidazole resistance in Clostridioides difficile
Microbiology SpectrumSince the emergence of epidemic Clostridioides difficile in the early 2000s, reduced susceptibility to metronidazole (MTZ), once a frontline antibiotic for treating C. difficile infection, has emerged.
Lillia Louis +3 more
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An in vitro study of the susceptibility of mobile and cystic forms of Borrelia burgdorferi to tinidazole [PDF]
, 2010 The susceptibility of mobile and cystic forms of Borrelia burgdorferi to tinidazole (TZ) was examined. The minimal bactericidal concentration (MBC) of TZ against the mobile spirochetes was >128 μg/ml at 37°C in micro-oxic atmosphere when incubated for 14
Sverre-Henning Brorson, Øystein Brorson
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Mechanisms of Tritrichomonas foetus Pathogenicity in Cats with Insights from Venereal Trichomonosis
Journal of Veterinary Internal Medicine, 2016 Almost 20 years has passed since trichomonosis was first recognized as a potential cause of diarrhea in domestic cats. Despite progress in confirming disease causation, developing means for diagnosis, and identifying approaches to treatment of the ...
M.K. Tolbert, J.L. Gookin
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SYNTHESES, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF 2-ARYL-4- QUINOLINE- CARBOXAMIDE DERIVATIVES [PDF]
Journal of Sciences, Islamic Republic of Iran, 1993 Reaction of aryl methyl ketone with isatin in the presence of a base afforded 2- arylquinoline-4-carboxylic acid (3). Reaction of diazomethane with compound 3 yielded the ester 4. Compound 5 was prepared from the reaction of N, N'-dialkylethyl (or propyl)
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