With nitrogen atoms in its structure, imidazole can form stable complexes with metal ions, making it a highly suitable ligand for the design of selective chemosensors.
Mohammad Goodarzi +4 more
doaj +1 more source
NITROIMIDAZOLES 111. [I]. SYNTHESIS, ANTIBACT - ERIAL AND ANTIFUNGAL ACTIVITY OF ZMETHYL - SU LFONYL -5 -(I-METHYL -5- NITRO-2- IMIDAZOLYL) 1,3,4-THIADIAZOLE [PDF]
2- Methylsulfonyl - 5- (1-methyl-5-nitro- 2 – imidazolyl ) 1,3,4 - thiadiazole ( 1 ) was prepared by twa independent routes.1) reaction of 1-methyl-2-formyl-5- nitroimidazole (3) with methyl hydrazinecarbodithioate gave the hydrazone 4.
doaj
Alkylation of 4-Nitroimidazole-5-Thiol With Alpha,Omega-Dihalides to Form Bicyclic Derivatives
The ammonium salt of 4-nitroimidazole-5-thiol is alkylated at N and S by 1,2-dichloroethane, 1,3-dibromopropane, and 1,4-dibromobutane to give bicyclic products.
ET Vanhorik, MR Grimmett, SR Kulkarni
core +1 more source
Updates in trichomonas treatment including persistent infection and 5-nitroimidazole hypersensitivity. [PDF]
Muzny CA, Van Gerwen OT, Kissinger P.
europepmc +1 more source
Enhancement of the antitrichomonal activity of 5-nitroimidazole derivatives by hydrogen peroxide
The in vitro sensitivity of nine Trichomonas vaginalis isolates to commonly employed 5-nitroimidazoles (metronidazole, nimorazole, ornidazole and tinidazole) was evaluated in absence and in presence of sub-inhibitory concentrations of hydrogen peroxide ...
V. PICCI +4 more
core
A systematic review of the literature on mechanisms of 5-nitroimidazole resistance in <i>Trichomonas vaginalis</i>. [PDF]
Graves KJ +5 more
europepmc +1 more source
Design, synthesis, in vitro inhibition and toxicological evaluation of human carbonic anhydrases I, II and IX inhibitors in 5-nitroimidazole series. [PDF]
Aspatwar A +8 more
europepmc +1 more source
A green, rapid, and simple HPLC-External standard method (ESM) and a quantitative analysis of multi- components with a single-marker (QAMS) method were established for the simultaneous determination of five nitroimidazole antimicrobials (Metronidazole ...
Baoxia Fang +3 more
doaj +1 more source
In vitro metabolic profile and drug-drug interaction assessment of secnidazole, a high-dose 5-nitroimidazole antibiotic for the treatment of bacterial vaginosis. [PDF]
Pentikis HS, Adetoro N, Kaufman G.
europepmc +1 more source
Design and Development of Small-Molecule Arylaldoxime/5-Nitroimidazole Hybrids as Potent Inhibitors of MARK4: A Promising Approach for Target-Based Cancer Therapy. [PDF]
Peerzada MN +6 more
europepmc +1 more source

