Results 121 to 130 of about 12,654,690 (210)

Trichomonas vaginalis Drug Targets and Their Role in Drug Discovery and Development. [PDF]

Pharm Res
Alves MSD, Sena-Lopes Â, Moron LD, Fonseca BDR, Borsuk S.   +4 more
europepmc   +1 more source

Molecular Mechanisms of Resistance and Treatment Efficacy of Delamanid Against <i>Mycobacterium tuberculosis</i>: A Systematic Review. [PDF]

Health Sci Rep
Islam MM, Hasan MZ, Tusar MTT, Hossain MY, Hossain MM, Jubayed MAA, Jubaer-Al-Abedin M, Soikot S, Akther S, Bhuyian J, Gazi HR, Hasan BMM, Azam MS, Haque ME, Abdullah-Al-Jubayer, Hasan MF, Haydar FMA, Khalekuzzaman M, Islam MT, Hasan S.   +19 more
europepmc   +1 more source

Indolequinone-Based Hypoxia-Activated Proteolysis Targeting Chimeras Selectively Degrade BRD4 in Hypoxic Cancer Cells. [PDF]

J Am Chem Soc
Serafini M, Twigger SA, Delfas G, Mallerman M, Bailey EP, Calder EDD, Hammond EM, Conway SJ.   +7 more
europepmc   +1 more source

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A comparative study on vibrational, conformational and electronic structure of 1,2-dimethyl-5-nitroimidazole and 2-methyl-5-nitroimidazole

Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2012
The FTIR and FT-Raman spectra of 1,2-dimethyl-5-nitroimidazole and 2-methyl-5-nitroimidazole have been recorded in the regions 4000-400 and 4000-100 cm(-1), respectively. The conformational analyses were performed and the energies of the different possible conformers were determined.
Velu Arjunan, R Santhanam
exaly   +4 more sources

Trichomoniasis refractory to 5-nitroimidazole therapy in Trinidad

Tropical Doctor, 2022
Trichomoniasis is the most common non-viral sexually transmitted infection (STI) occurring worldwide and the majority of infected persons (70–85%) have mild or no genital symptoms. Symptoms in women may include a vaginal discharge which may be associated with vulval irritation and most infections can be effectively treated with metronidazole 500mg bd ...
Robert Jeffrey Edwards, Miriam Parboo, Jonathan Edwards, Gregory Boyce   +3 more
openaire   +2 more sources

RM and log P values of 5-nitroimidazoles

Journal of Chromatography A, 1981
Abstract The chromatographic RM values of a series of nitroimidazoles and their log P values were determined in view of a study of their structure-activity relationships as mutagenic agents. The equations describing the relationship between RM and log P values show a low correlation coefficient.
GUERRA M.C., BARBARO A.M., CANTELLI FORTI G., FOFFANI M.T., BIAGI G.L., BOREA, Pier Andrea, FINI A.   +6 more
openaire   +1 more source

Development and validation of a QuEChERS method for the analysis of 5-nitroimidazole traces in infant milk-based samples by ultra-high performance liquid chromatography-tandem mass spectrometry.

Journal of Chromatography A, 2018
QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) methodology in combination with UHPLC-MS/MS is proposed for the determination of 5-nitroimidazole (5-NDZ) residues in infant milk-based products.
M. Hernández-Mesa, A. García-Campaña, C. Cruces‐Blanco   +2 more
semanticscholar   +1 more source