Results 81 to 90 of about 12,654,690 (210)

A new approach to study semi-coordination using two 2-methyl-5-nitroimidazole copper(ii) complexes of biological interest as a model system. [PDF]

RSC Adv, 2023
Fachini LG, Baptistella GB, Postal K, Santana FS, de Souza EM, Ribeiro RR, Nunes GG, Sá EL.   +7 more
europepmc   +1 more source

Reversion of heme-dependent metronidazole resistance in Clostridioides difficile

Microbiology Spectrum
Since the emergence of epidemic Clostridioides difficile in the early 2000s, reduced susceptibility to metronidazole (MTZ), once a frontline antibiotic for treating C. difficile infection, has emerged.
Lillia Louis, Firyal Ramzan, Dale D.O. Martin, Abiola O. Olaitan   +3 more
doaj   +1 more source

Mechanisms of Tritrichomonas foetus Pathogenicity in Cats with Insights from Venereal Trichomonosis

Journal of Veterinary Internal Medicine, 2016
Almost 20 years has passed since trichomonosis was first recognized as a potential cause of diarrhea in domestic cats. Despite progress in confirming disease causation, developing means for diagnosis, and identifying approaches to treatment of the ...
M.K. Tolbert, J.L. Gookin
doaj   +1 more source

SYNTHESES, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF 2-ARYL-4- QUINOLINE- CARBOXAMIDE DERIVATIVES [PDF]

Journal of Sciences, Islamic Republic of Iran, 1993
Reaction of aryl methyl ketone with isatin in the presence of a base afforded 2- arylquinoline-4-carboxylic acid (3). Reaction of diazomethane with compound 3 yielded the ester 4. Compound 5 was prepared from the reaction of N, N'-dialkylethyl (or propyl)
doaj  

Radiation Damage in Carnidazole: a Single Crystal EPR Study

CHIMIA, 1992
Single crystals of hydrated and anhydrous carnidazole have been subjected to X-irradiation at 77 K and studied by EPR. The determination of the EPR tensors shows that NO2, sulfur-centered radicals as well as a radical pair can be generated from ...
Théo Berclaz, Gérald Bernardinelli, Michel Geoffroy, Natarajan Rajalakshmi   +3 more
doaj   +2 more sources

Imidazole-based chemosensor for the detection of Ag+ ions: Antimicrobial activity, DFT insight, and molecular docking modeling

Results in Chemistry
With nitrogen atoms in its structure, imidazole can form stable complexes with metal ions, making it a highly suitable ligand for the design of selective chemosensors.
Mohammad Goodarzi, Ghodsi Mohammadi Ziarani, Zahra Panahande, Somayeh Reiisi, Mehran Feizi-Dehnayebi   +4 more
doaj   +1 more source

NITROIMIDAZOLES 111. [I]. SYNTHESIS, ANTIBACT - ERIAL AND ANTIFUNGAL ACTIVITY OF ZMETHYL - SU LFONYL -5 -(I-METHYL -5- NITRO-2- IMIDAZOLYL) 1,3,4-THIADIAZOLE [PDF]

Journal of Sciences, Islamic Republic of Iran, 1989
2- Methylsulfonyl - 5- (1-methyl-5-nitro- 2 – imidazolyl ) 1,3,4 - thiadiazole ( 1 ) was prepared by twa independent routes.1) reaction of 1-methyl-2-formyl-5- nitroimidazole (3) with methyl hydrazinecarbodithioate gave the hydrazone 4.
doaj  

Simultaneous determination of five nitroimidazole antimicrobials in pharmaceuticals using HPLC-ESM and QAMS methods

BMC Chemistry
A green, rapid, and simple HPLC-External standard method (ESM) and a quantitative analysis of multi- components with a single-marker (QAMS) method were established for the simultaneous determination of five nitroimidazole antimicrobials (Metronidazole ...
Baoxia Fang, Dan Jiang, Sicen Wang, Fuchao Chen   +3 more
doaj   +1 more source

In vitro metabolic profile and drug-drug interaction assessment of secnidazole, a high-dose 5-nitroimidazole antibiotic for the treatment of bacterial vaginosis. [PDF]

Pharmacol Res Perspect, 2020
Pentikis HS, Adetoro N, Kaufman G.
europepmc   +1 more source

Structure-enabled enhancement of potency in a metronidazole-benznidazole hybrid: design, synthesis, and evaluation of antitrypanosomal activity of a benzylamide-linked 5-nitroimidazole. [PDF]

Front Pharmacol
Velez ASMM, Chaves OA, Costa T, Serpa C, Borges JM, Freire-de-Lima CG, Decote-Ricardo D, Lima MEF.   +7 more
europepmc   +1 more source