Results 61 to 70 of about 14,177 (223)

Design, synthesis, reactivity, and biological activity of nitroimidazole derivatives and their copper(II) coordination compounds

Frontiers in Chemical Biology
In the last 60 years, the broad spectrum of activity of nitroimidazole derivatives against anaerobic bacteria, parasites, and protozoa has permitted their use as the first choice of treatment for many infectious diseases.
Walter Fugarolas, Lorena Reyes-Carmona, Bruno Landeros-Rivera, Argelia Almaguer-Flores, Norah Barba-Behrens   +4 more
doaj   +1 more source

Crystal structure of 1-(2-bromoethyl)-2-methyl-5-nitroimidazole, C6H8BrN3O2

Zeitschrift für Kristallographie - New Crystal Structures, 2006
C6H8BrN3O2, monoclinic, P121/a1 (no. 14), a = 6.3952(2) Å, b = 11.1267(3) Å, c = 12.0785(4) Å, β = 97.274(2)°, V = 852.6 Å3, Z = 4, Rgt(F) = 0.047, wRref(F2) = 0.128, T = 293 K.
Balliano T. L., Pereira M. A., De Simone C. A., Malta V. R. S., Velasquez N., Cioletti A. G, Goulart M. O. F.   +6 more
doaj   +1 more source

Antimicrobial Residues in a Key Cerrado River: Distribution, Persistence, and Effects on Zebrafish Embryo‐Larval Development

Environmental Toxicology, EarlyView.
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão, Igor Romeiro dos Santos, Jerônimo Raimundo de Oliveira Neto, Flávio Olimpio Sanches Neto, Felipe Cirqueira Dias, Jéssyca Moreira Morais, Lorranny Pereira de Assis Valadares, Naiara Raica Lopes de Oliveira, Mirelle Garcia Silva Bailão, Luiz Carlos da Cunha, Valter Henrique Carvalho‐Silva, Thiago Lopes Rocha, Elisa Flávia Luiz Cardoso Bailão   +12 more
wiley   +1 more source

Molecular dynamic simulation and inhibitor prediction of cysteine synthase structured model as a potential drug target for trichomoniasis [PDF]

, 2013
In our presented research, we made an attempt to predict the 3D model for cysteine synthase (A2GMG5-TRIVA) using homology-modeling approaches. To investigate deeper into the predicted structure, we further performed a molecular dynamics simulation for 10
Farmer, R, Gautam, B, Kumar, S, Sablok, G, Singh, AK, Singh, S   +5 more
core   +4 more sources

NITROIMIDAZOLES VII [I]. SYNTHESES, ANTIBACTERIAL AND ANTIFUNGAL ACT I V I T I E S OF 4 - S U B S T I T U T E D - 2 - TWIAZOLYLHYDRAZONES [PDF]

Journal of Sciences, Islamic Republic of Iran, 1990
Reaction of readily available 2-formyl -1-methyl-5-nitroimidazole (1) with 4-substituted-2-hydrazinothiazoles (2) afforded 2-formyl-l-methyl-5- nitroimidazole 4-substituted -2- thiazolylhydrazones (3).
doaj  

Use of ornidazole in the treatment of anaerobic infection in surgery

Perioperative Medicine, 2021
One of the most complex problems of modern surgery is the treatment and prevention of anaerobic infection. Main place in overcoming of this infectious complication is devoted to urgent surgical intervention and correct early empiric antibacterial therapy.
Yu M Babina, O A Nazarchuk, D V Dmytriiev   +2 more
doaj   +1 more source

A structured, behavioural science approach to the preparation of antimicrobial stewardship interventions for companion animal veterinarians

Veterinary Record, EarlyView.
Abstract Background A structured, behavioural science approach was adopted to develop antimicrobial stewardship interventions in UK first‐opinion companion animal veterinary practice. The objectives were to identify behavioural targets for intervention and to understand how practice contexts influence these behaviours.
Ben Walker, Dan O'Neill, Huw Stacey, Dave Brodbelt   +3 more
wiley   +1 more source

Certified reference materials for veterinary drugs [PDF]

, 2016
This leaflet summarises the CRMs for veterinary drugsJRC.D-Institute for Reference Materials and Measurements ...
LINSINGER Thomas
core  

EXPERIMENTAL AND THEORETICAL STUDY OF SHYNTESIS OF N-ALKYL-NITROIMIDAZOLES.

Vitae, 2010
In this work we realized and experimental and theoretical study of the N-alkylation of nitroimidazoles.The N-alkyl-2-methyl-nitroimidazoles correspond to biologically active molecules, obtained by reactionof 2-methyl-5-nitroimidazole and different alkyl ...
Constain SALAMANCA M., William TIZNADO V., Paula JARAMILLO G.   +2 more
doaj  

Synthesis of 1-[3-(2-methyl-5-nitro-1H-imidazol-1-yl)propyl]-1H-1,2,3-benzotriazole and 1-[3-(2-methyl-5-nitro-1H-imidazol-1-yl)butyl]-1H-1,2,3-benzotriazole

Molbank, 2006
n ...
Maria Grzegożek, Krystyna Nowak, Barbara Szpakiewicz   +2 more
doaj   +1 more source