Results 61 to 70 of about 88,028,942 (209)

Silent Contaminants: Antibiotic‐Resistant Bacteria in Food Systems

MicrobiologyOpen, Volume 15, Issue 6, December 2026.
This graphical abstract illustrates the “farm‐to‐fork” cycle of antibiotic resistance, highlighting how antibiotic use promotes resistant bacteria that spread through animals, crops, food, and humans, emphasizing the interconnected nature of antimicrobial resistance and the need for integrated One Health strategies to mitigate its global impact ...
Răzvan Odocheanu, Mădălina Lorena Medeleanu, Doru Pamfil, Dan Cristian Vodnar   +3 more
wiley   +1 more source

Antitrichomonal activity of 1-[(2, 4-dinitropyrryl)-ethyl]-2-methyl-5-nitroimidazole and related compounds

, 1965
A series of 1-substituted dinitropyrroles was tested for trichomonacidal activity. The shorter the substituent the greater was the in vitro activity. No relationship was found between in vivo activity and substituent length.
George W. Brown, Ralph Wellerson, Alfred B Kupferberg   +2 more
core   +1 more source

NITROIMIDAZOLES VII [I]. SYNTHESES, ANTIBACTERIAL AND ANTIFUNGAL ACT I V I T I E S OF 4 - S U B S T I T U T E D - 2 - TWIAZOLYLHYDRAZONES [PDF]

Journal of Sciences, Islamic Republic of Iran, 1990
Reaction of readily available 2-formyl -1-methyl-5-nitroimidazole (1) with 4-substituted-2-hydrazinothiazoles (2) afforded 2-formyl-l-methyl-5- nitroimidazole 4-substituted -2- thiazolylhydrazones (3).
doaj  

Synthesis of 1-[3-(2-methyl-5-nitro-1H-imidazol-1-yl)propyl]-1H-1,2,3-benzotriazole and 1-[3-(2-methyl-5-nitro-1H-imidazol-1-yl)butyl]-1H-1,2,3-benzotriazole

Molbank, 2006
n ...
Maria Grzegożek, Krystyna Nowak, Barbara Szpakiewicz   +2 more
doaj   +1 more source

The Broad Ecological Range of Salmonella enterica Serotype Typhimurium Is Associated With Genomic Diversification

Environmental Microbiology, Volume 28, Issue 11, November 2026.
The broad ecological range of Salmonella enterica serotype Typhimurium is associated with dynamic gain and loss of accessory genes, including plasmid‐associated antimicrobial resistance (AMR) genes, along with positive selection on core genes, potentially contributing to its differential adaptation across food animal and non‐food animal reservoirs ...
Leela Ohri, Sandeep Chinnareddy, Ying‐Xian Goh, Hailong Zhang, Xiangyu Deng, Amy Pruden, Rachel Cheng, Song Li, Jingqiu Liao   +8 more
wiley   +1 more source

In vitro trypanocidal activity of nitroimidazole derivatives [PDF]

, 2012
Chagas' disease, caused by the protozoan parasite Trypanosoma cruzi, affects 9-12 million of people in Latin America and it is an important cause of heart disease.
Ramos Ligonio, Ángel, López Monteon, Aracely, García Gálvez, Ana M., Sánchez Pavón, Esmeralda, Carrera Huerta, Francisco, Márquez López , Elizabeth   +5 more
core  

Structures cristallines du 4-bromo-2-méthoxy-1-méthyl-5-nitro et du 4-bromo-2-cyano-1-méthyl-5-nitroimidazoles obtenus par substitution nucléophile à partir du 2,4-dibromo-1-méthyl-5-nitroimidazole

, 1995
Reaction of 2,4-dibromo-1-methyl-5-nitroimidazole 1 with sodium methoxide in methanol or with potassium cyanide in DMSO implies univocal nucleophilic substitution of 2-bromine atom by methoxy or cyano group as revealed by the crystalline structures of 4 ...

core   +1 more source

Treatment strategies for nitroimidazole-refractory giardiasis: a systematic review

, 2021
Rationale for review: Giardiasis is one of the most common human protozoal infections worldwide. First-line therapy of giardiasis includes nitroimidazole antibiotics. However, treatment failure with nitroimidazoles is increasingly reported, with up to 45%
Bourque, Daniel L., Chen, L. H., Neumayr, Andreas, Bourque, D. L., Libman, Michael, Libman, M., Chen, Lin H., Neumayr, A., Michael Libman, Lin H Chen, Andreas Neumayr, Daniel L Bourque   +11 more
core   +1 more source

Ruthenium nitroimidazole complexes as radiosensitizers

, 1988
Local control of tumours by radiotherapy may fail due to the presence of regions of hypoxic cells. Radiosensitizers, such as nitroimidazoles, enhance killing of the resistant cells by ionizing radiation. However, dose limiting side-effects have prevented
Chan, Peter Ka-Lin
core   +1 more source

NITROIMIDAZOLES VIII [I]. SYNTHESES, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF 2-PYRIDYL-NITROIMIDAZOLES [PDF]

Journal of Sciences, Islamic Republic of Iran, 1990
Starting from 2-(2-pyridyl) imidazole a series of substituted imidazoles (2-5) were prepared. From the reaction of 2-(3-pyridyl) -4-(or 5) nitroimidazole (15) with dimethyl sulfate in alkaline medium 1-methyl-2-(3- pyridy1)-4-nitroimidazole (6,)w as ...
doaj