Results 151 to 160 of about 12,654,690 (210)

A new synthetic approach for novel 4-substituted-5-nitroimidazoles

Tetrahedron Letters, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Maxime D. Crozet, Patricia Perfetti, Mustapha Kaafarani, Patrice Vanelle, Michel P. Crozet   +4 more
openaire   +1 more source

Voltammetric determination of 5-nitroimidazole derivatives in honey and HPLC-MS/MS confirmation

Journal of Food Measurement & Characterization, 2021
K. Plotnikova, L. Dubenska, P. Rydchuk, Solomiya Pysarevska, Mariana Rydchuk, Sofiia Ivakh, D. Yanovych, Z. Zasadna, S. Plotycya   +8 more
semanticscholar   +1 more source

Lowering of 5-nitroimidazole's mutagenicity: Towards optimal antiparasitic pharmacophore

European Journal of Medicinal Chemistry, 2009
To improve the antiparasitic pharmacophore, 20 5-nitroimidazoles bearing an arylsulfonylmethyl group were prepared from commercial imidazoles. The antiparasitic activity of these molecules was assessed against Trichomonas vaginalis, the in vitro cytotoxicity was evaluated on human monocytes and the mutagenicity was determined by the Salmonella ...
Maxime D, Crozet, Céline, Botta, Monique, Gasquet, Christophe, Curti, Vincent, Rémusat, Sébastien, Hutter, Olivier, Chapelle, Nadine, Azas, Michel, De Méo, Patrice, Vanelle   +9 more
openaire   +2 more sources

Resistance to 5-Nitroimidazoles in Pathogenic Microorganisms

1982
Resistance (lowered susceptibility) to metronidazole and other 5-nitroimidazoles occurs, albeit infrequently, in clinical isolates of the normally susceptible anaerobic microorganisms, Trichomonas vaginalis and Bacteroides spp. Such resistance has been induced by in vivo drug pressure in T.
openaire   +1 more source

Hydrogenosome: The Site of 5-Nitroimidazole Activation and Resistance

2007
Derivatives of 5-nitroimidazole, such as metronidazole or tinidazole, are the drugs of choice for treatment of sexually transmitted infections of humans caused by the parasitic protist Trichomonas vaginalis. These drugs with selective activity against anaerobic and microaerophilic microorganisms enter the trichomonad cell and accumulate in ...
Jaroslav Kulda, Ivan Hrdý
openaire   +1 more source

2-Amino-5-nitroimidazoles

Journal of Medicinal Chemistry, 1971
L F, Miller, R E, Bambury
openaire   +2 more sources

Activation in vivo of 5-nitroimidazoles

Mutation Research/Environmental Mutagenesis and Related Subjects, 1982
M.A. Belisario, F. De Lorenzo, E. De Marinis   +2 more
openaire   +1 more source

Treatment strategies for nitroimidazole-refractory giardiasis: a systematic review

Journal of Travel Medicine, 2022
Andreas Neumayr, Lin H Chen, Daniel Bourque   +2 more
exaly  

2-Methyl-5-nitroimidazole

2021
openaire   +1 more source

Identification of novel 1‐indolyl acetate‐5‐nitroimidazole derivatives of combretastatin A‐4 as potential tubulin polymerization inhibitors

Biochemical Pharmacology, 2017
Yongfang Yao, Zhong-Chang Wang, Song-Yu Wu, Qing-Fang Li, Chen Yu, Xin‐Yi Liang, Pengcheng Lv, Y. Duan, Hailiang Zhu   +8 more
semanticscholar   +1 more source