Results 11 to 20 of about 88,028,942 (209)

Fragmentation patterns of 4(5)‐nitroimidazole and 1‐methyl‐5‐nitroimidazole—The effect of the methylation [PDF]

Journal of Mass Spectrometry, 2017
AbstractWe present here the photofragmentation patterns of doubly ionized 4(5)‐nitroimidazole and 1‐methyl‐5‐nitroimidazole. The doubly ionized state was created by core ionizing the C 1s orbitals of the samples, rapidly followed by Auger decay. Due to the recent development of nitroimidazole‐based radiosensitizing drugs, core ionization was selected ...
Eero Itälä, Katrin Tanzer, Sari Granroth, Kuno Kooser, Stephan Denifl, Edwin Kukk   +5 more
openaire   +4 more sources

Management of Trichomoniasis in the Setting of 5-Nitroimidazole Hypersensitivity. [PDF]

Sex Transm Dis, 2021
Abstract Metronidazole and other 5-nitroimidazoles are the mainstay of Trichomonas vaginalis treatment, with few efficacious and safe treatment options available outside of this class. Patients with trichomoniasis and a history of a clinically confirmed hypersensitivity reaction to 5-nitroimidazoles present a management challenge for ...
Van Gerwen OT, Camino AF, Bourla LN, Legendre D, Muzny CA.   +4 more
europepmc   +3 more sources

Using 5-Nitroimidazole Derivatives against Neglected Tropical Protozoan Diseases: Systematic Review

Future Pharmacology, 2020
Neglected tropical diseases (NTDs) are a significant global health problem. Additionally, anti-protozoan treatments are toxic, and their therapeutic regimens require prolonged treatment times and high concentrations of the drugs.
Micheel M. Vichi-Ramírez, Edgar López-López, Catalina Soriano-Correa, Carolina Barrientos-Salcedo   +3 more
doaj   +2 more sources

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

Nitroimidazole-Based Ruthenium(II) Complexes: Playing with Structural Parameters to Design Photostable and Light-Responsive Antibacterial Agents

, 2021
5-Nitroimidazole (5NIMH), chosen as a molecular model of nitroimidazole derivatives, which represent a broad-spectrum class of antimicrobials, was incorporated into the ruthenium complexes [Ru­(tpy)­(phen)­(5NIM)]­PF6 (1) and [Ru­(tpy)­(dmp)­(5NIM)]­PF6 (
Claudia Giorgi (1719847), Camilla Fagorzi, Giangaetano Pietraperzia, Barbara Valtancoli, Claudia Giorgi, Annalisa Guerri (1779556), Alessio Mengoni (619628), Alessio Mengoni, Ilaria Palchetti (698770), Gina Elena Giacomazzo (11726598), Marco Pagliai (1282797), Camilla Fagorzi (5814413), Barbara Valtancoli (1960708), Gina Elena Giacomazzo, Patrick Severin Sfragano, Luca Conti, Marco Pagliai, Giangaetano Pietraperzia (1736587), Ilaria Palchetti, Annalisa Guerri, Luca Conti (5872802), Patrick Severin Sfragano (11726601)   +21 more
core   +1 more source

In-vitro studies of two 5-nitroimidazole derivatives [PDF]

Journal of Antimicrobial Chemotherapy, 1997
This paper reports the findings obtained using two new compounds belonging to the 5-nitroimidazole family: sulphuridazole (V1) and sulphonidazole (V2). We first assessed their antimicrobial activity on Clostridia spp. and then extended the study to Gram-positive and Gram-negative aerobic microorganisms and to Candida albicans.
M, Castelli, M, Malagoli, A I, Ruberto, A, Baggio, C, Casolari, C, Cermelli, M R, Bossa, T, Rossi, F, Paolucci, S, Roffia   +9 more
openaire   +2 more sources

Bacterial vaginosis: comparative effectiveness of treatments with 5-nitroimidazole derivatives [PDF]

РМЖ. Мать и дитя, 2023
I.G. Kutsenko, I.O. Borovikov, E.I. Kravtsova, S.K. Batmen, A.S. Magay, O.I. Borovikova, V.A. Avakimyan, A.A. Andreeva Kuban State Medical University, Krasnodar, Russian Federation Aim: to perform a comparative analysis of clinical and ...
I.G. Kutsenko, I.O. Borovikov, E.I. Kravtsova, S.K. Batmen, A.S. Magay, O.I. Borovikova, V.A. Avakimyan, A.A. Andreeva   +7 more
doaj  

The crystal structure of 5-amino-1-methyl-4-nitroimidazole, C4H6O2N4

Zeitschrift für Kristallographie - New Crystal Structures, 2023
C4H6O2N4, monoclinic, P2/c (no. 13), a = 14.6016(14) Å, b = 6.2077(6) Å, c = 12.9876(11) Å, β = 100.742(3)∘, V = 1156.60(19) Å3, Z = 8, Rgt(F) = 0.0656, wRref(F2) = 0.1524, T = 170 K .
Cai Cao, Yumin Yan, Zhiwei Wen, Pengbao Lian, Jianlong Wang   +4 more
doaj   +1 more source

Comparative Effectiveness of Treatments for Bacterial Vaginosis: A Network Meta-Analysis

Antibiotics, 2021
Bacterial vaginosis (BV) is a common vaginal dysbiosis in women of reproductive age. However, the cure rate for BV varies considerably and many women experience a relapse after the initial treatment.
Alison Muñoz-Barreno, Fausto Cabezas-Mera, Eduardo Tejera, António Machado   +3 more
doaj   +1 more source