Results 11 to 20 of about 14,177 (223)
Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]
, 2016 Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
A +173 more
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Periodontology 2000, EarlyView., 2023 Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera +4 more
wiley +1 more source
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Synthesis of N-7-Substituted Purines from Imidazole Precursors
Molecules, 1999 Synthesis of purines and purine mono-1-oxides from the respective 5-substituted 4-nitroimidazole derivatives is described. The commercially available 4-nitroimidazole, in a few simple steps (including Vicarious Nucleophilic Substitution of Hydrogen), was
Stanislaw Ostrowski
doaj +1 more source
TLC–Densitometric Analysis of Selected 5-Nitroimidazoles
Processes, 2023 Metronidazole, ornidazole, tinidazole, and secnidazole are 5-nitroimidazoles. The purpose of this work was to propose a new economical TLC–densitometric method to evaluate the chemical stability of metronidazole, secnidazole, ornidazole, and tinidazole under stress conditions. A forced degradation study was performed on silica gel and aqueous solutions
openaire +2 more sources
In-vitro studies of two 5-nitroimidazole derivatives [PDF]
Journal of Antimicrobial Chemotherapy, 1997 This paper reports the findings obtained using two new compounds belonging to the 5-nitroimidazole family: sulphuridazole (V1) and sulphonidazole (V2). We first assessed their antimicrobial activity on Clostridia spp. and then extended the study to Gram-positive and Gram-negative aerobic microorganisms and to Candida albicans.
M, Castelli +9 more
openaire +2 more sources
Metronidazole resistance: a hidden epidemic? [PDF]
, 2018 This is a personal reflection from working as a clinical microbiologist and becoming increasingly concerned over gaps in our knowledge of metronidazole resistance and its impact on clinical ...
Smith, Andrew
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The crystal structure of 5-amino-1-methyl-4-nitroimidazole, C4H6O2N4
Zeitschrift für Kristallographie - New Crystal Structures, 2023 C4H6O2N4, monoclinic, P2/c (no. 13), a = 14.6016(14) Å, b = 6.2077(6) Å, c = 12.9876(11) Å, β = 100.742(3)∘, V = 1156.60(19) Å3, Z = 8, Rgt(F) = 0.0656, wRref(F2) = 0.1524, T = 170 K .
Cai Cao +4 more
doaj +1 more source
Bacterial vaginosis: comparative effectiveness of treatments with 5-nitroimidazole derivatives [PDF]
РМЖ. Мать и дитя, 2023 I.G. Kutsenko, I.O. Borovikov, E.I. Kravtsova, S.K. Batmen, A.S. Magay, O.I. Borovikova, V.A. Avakimyan, A.A. Andreeva Kuban State Medical University, Krasnodar, Russian Federation Aim: to perform a comparative analysis of clinical and ...
I.G. Kutsenko +7 more
doaj
Comparative Effectiveness of Treatments for Bacterial Vaginosis: A Network Meta-Analysis
Antibiotics, 2021 Bacterial vaginosis (BV) is a common vaginal dysbiosis in women of reproductive age. However, the cure rate for BV varies considerably and many women experience a relapse after the initial treatment.
Alison Muñoz-Barreno +3 more
doaj +1 more source