Results 31 to 40 of about 88,028,942 (209)
Synthesis of New Active Sulfones in the 5-Nitroimidazole Series
Molecules, 2002 We describe here the preparation of new 5-nitroimidazoles which are known to have an efficacy against metronidazole-susceptible and -resistant Giarda, Trichomonas, and Entamoeba spp. The multi-step synthesis uses electron transfer methodology.
Patrice Vanelle +2 more
doaj +1 more source
Compounds, 2023 The discovery of azomycin provided the major impulse for the systematic search for medicines showing activity against anaerobic protozoa. Nowadays, many other interesting applications have been found for nitroimidazoles as therapeutic agents.
Justyna Żwawiak, Lucjusz Zaprutko
doaj +1 more source
Decomposition of nitroimidazole ions: experiment and theory [PDF]
, 2015 International audienceNitroimidazoles are important compounds with chemotherapeutic applications as antibacterial drugs or as radiosensitizers in radiotherapy. Despite their use in biological applications, little is known about the fundamental properties
O'Hair, R.A..J. +12 more
core +1 more source
Journal of Clinical and Translational Science, 2022 OBJECTIVES/GOALS: 5-nitroimidazoles are the only FDA-approved medications for T. vaginalis treatment. Resistance has been observed in 5-10% of cases, but may be rising. We aimed to delineate mechanisms of resistance in isolates of T.
Keonte Graves +7 more
doaj +1 more source
Antibiotic residues in poultry‐derived foods and associated human health risks: a systematic review
Journal of the Science of Food and Agriculture, EarlyView.Abstract Antibiotic residues in poultry‐derived foods remain a food‐safety concern because of their implications for regulatory compliance, antimicrobial stewardship, and consumer exposure. This review synthesized evidence published between 2016 and April 2026 on the occurrence of antibiotic residues in poultry‐derived foods, analytical approaches ...
Ana Clara Nogueira Alves +3 more
wiley +1 more source
The Hepatocellular Hypoxia Criteria:2’Nitroimidazole Effect on Hepatocyte Carbohydrate Metabolizing Enzymes [PDF]
, 2008 Aim: to understand the 2’-nitroimidazole induced hypoxia and liver cell interaction, we proposed a “Hapatocellular Hypoxia Criteria”.
Rakesh Sharma
core
Smart Molecules, EarlyView.Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão +12 more
wiley +1 more source
Common pathways and outliers in glucose catabolism across Trypanosomatidae
The FEBS Journal, EarlyView.Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes +5 more
wiley +1 more source
1-Hydroxyethyl-2-methyl-5-nitroimidazolium 3-carboxy-4-hydroxybenzenesulfonate
Acta Crystallographica Section E, 2008 Cocrystallization of 1-hydroxyethyl-2-methyl-5-nitroimidazole (metronidazole) and 5-sulfosalicylic acid (5-H2SSA) from methanol solution yields the title salt, C6H10N3O3+·C7H5O6S−. In the crystal structure, the ions are linked by a combination
Bo Yang
doaj +1 more source