Results 21 to 30 of about 88,028,942 (209)
Synthetic and antimicrobial studies of nitroimidazole analogues
, 1988 New 2-, 4- and 5-nitroimidazole analogues were synthesised using the following methods: (i) SRN1 free radical reaction between nitroimidazole anion and halonitro substrates; (ii) oxidative addition of the anion of 2-nitropropane to nitroimidazole anions.
Adelaide T.O.M. Adebayo (7167011)
core +3 more sources
Michael-type addition of azoles of broad-scale acidity to methyl acrylate
Beilstein Journal of Organic Chemistry, 2011 An optimisation of Michael-type addition of azole derivatives of broad-scale acidity – ranging from 5.20 to 15.00 pKa units – namely 4-nitropyrazole, 3,5-dimethyl-4-nitropyrazole, 4(5)-nitroimidazole, 4,5-diphenylimidazole, 4,5-dicyanoimidazole, 2-methyl-
Sławomir Boncel +3 more
doaj +1 more source
The crystal structure of 5-azido-1-methyl-4-nitroimidazole, C4H4O2N6
Zeitschrift für Kristallographie - New Crystal Structures, 2022 C4H4O2N6, monoclinic, P21/c (no. 14), a = 11.633(3) Å, b = 8.899(3) Å, c = 6.7638(18) Å, β = 105.216(12)°, V = 675.6(4) Å3, Z = 4, Rgt (F) = 0.0607, wRref (F 2) = 0.1617, T = 170 K.
Huipeng Zhao +4 more
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Development of a Rapid Chemical Identification System (RCIS) for the Detection of Fraudulently Labelled 5-nitroimidazole Products [PDF]
, 2010 Purpose: A simple, reliable and rapid chemical identification system (RCIS) consisting of three colour reactions based on the functional groups in the molecule and two TLC methods was developed for preliminary detection of the 5–nitroimidazole drugs ...
Awofisayo, OA +5 more
core +4 more sources
Iraqi Journal of Pharmaceutical Sciences, 2021 Secnidazole was linked with ciprofloxacin as mutual prodrugs to get antibiotics with broader spectrum of activity, improved physicochemical properties and given by single dose to improve patient’s compliance.
Marwah W. Khalid +2 more
doaj +1 more source
TLC–Densitometric Analysis of Selected 5-Nitroimidazoles
Processes, 2023 Metronidazole, ornidazole, tinidazole, and secnidazole are 5-nitroimidazoles. The purpose of this work was to propose a new economical TLC–densitometric method to evaluate the chemical stability of metronidazole, secnidazole, ornidazole, and tinidazole under stress conditions. A forced degradation study was performed on silica gel and aqueous solutions
openaire +2 more sources
Coupling of C-nitro-NH-azoles with arylboronic acids. A route to N-aryl-C-nitroazoles
Beilstein Journal of Organic Chemistry, 2013 A method for the synthesis of N-aryl-C-nitroazoles is presented. A coupling reaction between variously substituted arylboronic acids and 3(5)-nitro-1H-pyrazole catalyzed by copper salt has been carried out in methanol in the presence of sodium hydroxide ...
Marta K. Kurpet +5 more
doaj +1 more source
Journal of Integrated Health Sciences, 2016 Background: The development of resistant with the current antibiotics increases the need for discovery of more efficient drugs for the treatment of infections.
D G Desai +4 more
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Determining a Treatment Regimen With Optimal Pregnancy Outcomes in Patients With Chronic Endometritis: A Systematic Review and Network Meta‐Analysis [PDF]
Health Sci RepABSTRACT Background and Aims Chronic endometritis (CE) negatively impacts pregnancy outcomes. This study aimed to compare the efficacy of various treatment regimens on pregnancy outcomes in women with CE. Methods We performed a systematic review followed by an NMA in accordance with the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses
Gong Z +7 more
europepmc +2 more sources
Molecules, 2017 A one-pot regioselective bis-Suzuki-Miyaura or Suzuki-Miyaura/Sonogashira reaction on 2,4-dibromo-1-methyl-5-nitro-1H-imidazole under microwave heating was developed.
Fanny Mathias +7 more
doaj +1 more source