Results 161 to 170 of about 9,556,040 (196)

Elucidating the Role of Protandim and 6‐Gingerol in Protection Against Osteoarthritis

Journal of Cellular Biochemistry, 2017
ABSTRACTProtandim and 6‐gingerol, two potent nutraceuticals, have been shown to decrease free radicals production through enhancing endogenous antioxidant enzymes. In this study, we evaluated the effects of these products on the expression of different factors involved in osteoarthritis (OA) process.
Abusarah, Jamilah, Benabdoune, Houda, Shi, Qin, Lussier, Bertrand, Martel-Pelletier, Johanne, Malo, Michel, Fernandes, Julio C., de Souza, Fátima Pereira, Fahmi, Hassan, Benderdour, Mohamed   +9 more
openaire   +3 more sources

Mechanism of Inhibition of Peroxynitrite-Induced Oxidation and Nitration by [6]-Gingerol

Planta Medica, 2005
[6]-Gingerol potently inhibits peroxynitrite-induced oxidation and nitration reactions, but its mechanism of action is unclear. In order to discover the mechanism of inhibition, [6]-gingerol was reacted with peroxynitrite and the reaction mixture was analyzed using HPLC.
Katsunari, Ippoushi, Hidekazu, Ito, Hideki, Horie, Keiko, Azuma   +3 more
openaire   +2 more sources

Antioxidant actions of thymol, carvacrol, 6-gingerol, zingerone and hydroxytyrosol

Food and Chemical Toxicology, 1994
Antioxidants minimize oxidation of the lipid components in foods. There is an increasing interest in the use of natural and/or synthetic antioxidants in food preservation, but it is important to evaluate such compounds fully for both antioxidant and pro-oxidant properties.
R, Aeschbach, J, Löliger, B C, Scott, A, Murcia, J, Butler, B, Halliwell, O I, Aruoma   +6 more
openaire   +2 more sources

Biotransformation of 6-gingerol and 6-shogaol by Aspergillus niger

Phytochemistry, 1993
Abstract 6-Gingerol and shogaol, the pungent constituents of Zingiber officinalis were biotransformed by Aspergillus niger. 6-Gingerol was converted to the corresponding primary alcohol as major product although a keto group is present in the molecule whereas the double bond and keto group of 6-shogaol were reduced and the terminal methyl group was ...
Hironobu Takahashi, Toshihiro Hashimoto, Yoshiaki Noma, Yoshinori Asakawa   +3 more
openaire   +1 more source

Crystal Structure and Antioxidant Activity of 6-Gingerol Oxime

Applied Mechanics and Materials, 2014
Under the acidic condition, 6-gingerol (C17H26O4) reacted with hydroxylamine to generate 6-gingerol oxime (C17H27NO4). Single-crystal X-ray diffraction with CuKα radiation (λ = 1.54184 Å) revealed the crystal belongs to the orthorhombic system, the space ground is P212121 with a = 5.24240(10), b = 25.7792(4), c = 25.9824(5) Å, V = 3511.39(11) Å3, Z =
Na Wang, Si Yu Liu, Xue Song Huang
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ChemInform Abstract: Synthesis of Chiral Difluorinated (6)‐Gingerol.

ChemInform, 1996
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
H. FUKUDA, M. TETSU, T. KITAZUME
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Biosynthesis of [6]-gingerol, pungent principle of Zingiber officinale

Journal of the Chemical Society, Chemical Communications, 1976
Evidence is adduced for a scheme of bio-synthesis for (S)-(+)-[6]-gingerol in Zingiber officinale Roscoe, in which dihydroferulate is built up from phenylalanine and participates in a new example of a ‘biological Claisen reaction’ with malonate and hexanoate; the β-diketone product is then reduced to [6]-gingerol.
Phillip Denniff, Donald A. Whiting
openaire   +1 more source

6-Gingerol induces autophagy to protect HUVECs survival from apoptosis

Chemico-Biological Interactions, 2016
6-Gingerol, the major pharmacologically-active component of ginger, has the potential to prevent heart disease. However, the mechanisms are not well understood. In this study, the protective effect of 6-gingerol against hydrogen peroxide-induced apoptosis in human umbilical vein endothelial cells (HUVECs) was investigated.
Shaopeng, Wang, Xiance, Sun, Liping, Jiang, Xiaofang, Liu, Min, Chen, Xiaofeng, Yao, Qinghua, Sun, Guang, Yang   +7 more
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[6]-Gingerol, a pungent ingredient of ginger, inhibits angiogenesis in vitro and in vivo

Biochemical and Biophysical Research Communications, 2005
[6]-Gingerol, a pungent ingredient of ginger (Zingiber officinale Roscoe, Zingiberaceae), has anti-bacterial, anti-inflammatory, and anti-tumor-promoting activities. Here, we describe its novel anti-angiogenic activity in vitro and in vivo. In vitro, [6]-gingerol inhibited both the VEGF- and bFGF-induced proliferation of human endothelial cells and ...
Eok-Cheon, Kim, Jeong-Ki, Min, Tae-Yoon, Kim, Shin-Jeong, Lee, Hyun-Ok, Yang, Sanghwa, Han, Young-Myeong, Kim, Young-Guen, Kwon   +7 more
openaire   +2 more sources

[Inhibition effect of 6-gingerol on hair growth].

Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery, 2015
To investigate the effect of 6-gingerol, the main active component of ginger, on hair shaft elongation in vitro and hair growth in vivo.Firstly, Hair follicles were co-cultured with 3 different concentration of 6-gingerol for 5 days and hair elongation in three groups was measured.
Yong, Miao, Ya-Bin, Sun, Wen-Jun, Wang, Zhi-Dan, Zhang, Jin-Dou, Jiang, Ze-Hua, Li, Zhi-Qi, Hu   +6 more
openaire   +1 more source