Results 101 to 110 of about 7,966 (172)

Response to 'The end of the dosage of 6 Thioguanine nucleotides? Not so sure…'. [PDF]

J Crohns Colitis, 2018
Waljee AK, Sauder K, Patel A, Segar S, Zhang Y, Zhu J, Stidham RW, Balis U, Higgins PDR.   +8 more
europepmc   +1 more source

Hepatotoxicity during 6-thioguanine treatment in inflammatory bowel disease and childhood acute lymphoblastic leukaemia: A systematic review. [PDF]

PLoS One, 2019
Toksvang LN, Schmidt MS, Arup S, Larsen RH, Frandsen TL, Schmiegelow K, Rank CU.   +6 more
europepmc   +1 more source

6-Thioguanine and Its Analogs Promote Apoptosis of Castration-Resistant Prostate Cancer Cells in a BRCA2-Dependent Manner. [PDF]

Cancers (Basel), 2019
Laera L, Guaragnella N, Giannattasio S, Moro L.   +3 more
europepmc   +1 more source

6-Thioguanine is a noncompetitive and slow binding inhibitor of human deubiquitinating protease USP2. [PDF]

Sci Rep, 2018
Chuang SJ, Cheng SC, Tang HC, Sun CY, Chou CY.   +4 more
europepmc   +1 more source

6-Thioguanine inhibits rotavirus replication through suppression of Rac1 GDP/GTP cycling. [PDF]

Antiviral Res, 2018
Yin Y, Chen S, Hakim MS, Wang W, Xu L, Dang W, Qu C, Verhaar AP, Su J, Fuhler GM, Peppelenbosch MP, Pan Q.   +11 more
europepmc   +1 more source

Porcine epidemic diarrhea virus papain-like protease 2 can be noncompetitively inhibited by 6-thioguanine. [PDF]

Antiviral Res, 2018
Chu HF, Chen CC, Moses DC, Chen YH, Lin CH, Tsai YC, Chou CY.   +6 more
europepmc   +1 more source

6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro protease activities

, 2020
Swaim CD, Perng Y, Zhao X, Canadeo LA, Harastani HH, Darling TL, Boon ACM, Lenschow DJ, Huibregtse JM.   +8 more
europepmc   +1 more source

NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine. [PDF]

Cancer Res, 2016
Valerie NC, Hagenkort A, Page BD, Masuyer G, Rehling D, Carter M, Bevc L, Herr P, Homan E, Sheppard NG, Stenmark P, Jemth AS, Helleday T.   +12 more
europepmc   +1 more source

Nucleoside diphosphate-linked moiety X-type motif 15 R139C genotypes impact 6-thioguanine nucleotide cut-off levels to predict thiopurine-induced leukopenia in Crohn's disease patients. [PDF]

World J Gastroenterol, 2019
Zhu X, Chao K, Li M, Xie W, Zheng H, Zhang JX, Hu PJ, Huang M, Gao X, Wang XD.   +9 more
europepmc   +1 more source

A drug-repositioning screen for primary pancreatic ductal adenocarcinoma cells identifies 6-thioguanine as an effective therapeutic agent for TPMT-low cancer cells. [PDF]

Mol Oncol, 2018
Kim I, Choi YS, Song JH, Choi EA, Park S, Lee EJ, Rhee JK, Kim SC, Chang S.   +8 more
europepmc   +1 more source