Results 21 to 30 of about 920 (179)

Associations of Serum Substituted p-Phenylenediamine-Derived Quinone Levels with Oxidative Stress and Immune Function Biomarkers in a General Adult Population [PDF]

open access: yesToxics
Substituted p-phenylenediamine-quinones (PPD-Qs) are commonly employed as antioxidants in varying rubbers with potential biotoxicological implications in humans.
Dandan Zhou   +8 more
doaj   +2 more sources

Respiratory toxicity mechanism of 6PPD and 6PPD-quinone: An integrated study based on network toxicology and molecular docking

open access: yesEcotoxicology and Environmental Safety
The widespread distribution of environmental contaminants poses a significant threat to public health. N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its ozone-derivative, 6PPD-quinone (6PPD-Q), are emerging pollutants that propagate ...
Gang Li   +6 more
doaj   +3 more sources

What evidence exists on the environmental occurrence and toxic effects of the tire additive 6PPD: a systematic map protocol [PDF]

open access: yesEnvironmental Evidence
Background The tire additive N-(1,3-dimethylbutyl)-Nʹ-phenyl-p-phenylenediamine (6PPD) is widely produced in large volumes as a rubber antidegradant. This chemical can be released into the environment throughout the lifecycle of rubber products. Recently,
Katryna J. Seabrook   +10 more
doaj   +2 more sources

Residues of 6PPD-Q in the Aquatic Environment and Toxicity to Aquatic Organisms: A Review

open access: yesFishes
N-(1,3-dimethylbutyl)-N’-phenyl-p-benzoquinone (6PPD-Q) is an emerging environmental contaminant that is widely distributed in aquatic environments and presents significant toxicological risks to aquatic organisms.
Chaoju Li   +5 more
doaj   +2 more sources

Environmental and Human Health Risks of 6PPD and 6PPDQ: Assessment and Implications [PDF]

open access: yesToxics
This review aims to synthesize current knowledge on the environmental contaminants N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its quinone derivative (6PPDQ) derived from tire wear particles (TWPs), focusing on their environmental ...
Sainan Zhang   +5 more
doaj   +2 more sources

6PPD and 6PPD-Q Induce Mitochondrial Dysfunction in <i>Saccharomyces cerevisiae</i>. [PDF]

open access: yesInt J Mol Sci
N-(1,3-dimethylbutyl)-N′phenyl-p-phenylenediamine, more commonly known as 6PPD, is a tire antiozonant used to prevent rubber oxidation and degradation. When 6PPD reacts with ozone, it becomes 6PPD-Quinone (6PPD-Q).
Braun E, Metcalf M, Kim K.
europepmc   +2 more sources

Correlation between 6PPD-Q and immune along with metabolic dysregulation induced liver lesions in outdoor workers

open access: yesEnvironment International
Outdoor workers who are exposed to traffic-derived pollutants often suffer from a range of diseases, with liver disease being particularly notable. Recently, a rubber stabilizing additive antioxidant N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine ...
Zhihao Qin   +8 more
doaj   +2 more sources

Tire-derived contaminants 6PPD and 6PPD-Q: Analysis, sample handling, and reconnaissance of United States stream exposures

open access: yesChemosphere
The environmental ubiquity of tire and road wear particles (TRWP) underscores the need to understand the occurrence, persistence, and environmental effects of tire-related chemicals in aquatic ecosystems. One such chemical is 6PPD-quinone (6PPD-Q), a transformation product of the tire antioxidant 6PPD. In urban stormwater runoff 6PPD-Q can exceed acute
Justin B Greer   +2 more
exaly   +3 more sources

Unveiling the Molecular Mechanism of 6PPD and 6PPD-Q in Lipid-Metabolism-Related Diseases Through Network Toxicology and Experimental Validation. [PDF]

open access: yesInt J Mol Sci
6PPD and its ozonation product 6PPD-quinone (6PPD-Q) are ubiquitous tire-derived pollutants linked to environmental and potential human health risks.
Li Z, Luo Y, Zhao J, Wang S, Zhang Y.
europepmc   +2 more sources

Chiral perspective evaluations: Enantioselective hydrolysis of 6PPD and 6PPD-quinone in water and enantioselective toxicity to Gobiocypris rarus and Oncorhynchus mykiss

open access: yesEnvironment International, 2022
As a ubiquitous tire antidegradant, N-(1,3-dimethylbutyl)-N’-phenyl-p-phenylenediamine (6PPD) is persistently released into the environment. It is highly toxic to aquatic organisms, and its transformation product 6PPD-quinone (6PPD-Q), is “very highly ...
Shanshan Di   +8 more
doaj   +1 more source

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