Chronic toxicity mechanisms of 6PPD and 6PPD-Quinone in zebrafish [PDF]
Environmental Science and EcotechnologyN-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its oxidation derivative, 6PPD-quinone (6PPDQ), have been extensively detected in environmental and biological samples, raising significant concerns regarding their chronic aquatic toxicity at
Fang Jiao +7 more
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Investigation of 6PPD-Quinone in Rubberized Asphalt Concrete Mixtures [PDF]
ACS Environmental Au, 2023 N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD)-quinone (6PPD-Q), a transformation byproduct of 6PPD used in tires as an antiozonant and antioxidant, was recently discovered as the chemical primarily responsible for the acute lethal toxicity of urban storm runoff to coho salmon. The asphalt concrete (AC) surface layer is the primary medium to
Srinidhi Lokesh +4 more
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A Review of N-(1,3-Dimethylbutyl)-N′-phenyl-p-Phenylenediamine (6PPD) and Its Derivative 6PPD-Quinone in the Environment [PDF]
ToxicsAs an antioxidant and antiozonant, N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) is predominantly used in the rubber industry to prevent degradation.
Yi Li +10 more
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Not Just a Fish Killer: Multi-Organ Toxicity and Mechanisms of 6PPD-Quinone [PDF]
Toxics6PPD-Quinone (6PPD-Q) is a tire derivative formed by the oxidation of N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD), a commonly used antioxidant and ozone stabilizer in rubber products, and has emerged as a significant environmental concern ...
Pinzhi Dong +7 more
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6PPD-quinone affects the photosynthetic carbon fixation in cyanobacteria by extracting photosynthetic electrons [PDF]
The InnovationPhotosynthetic carbon fixation by cyanobacteria plays a pivotal role in the global carbon cycle but is threatened by environmental pollutants. To date, the impact of quinones, with electron shuttling properties, on cyanobacterial photosynthesis is ...
Xiuqi You +7 more
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The Tire Wear Compounds 6PPD-Quinone and 1,3-Diphenylguanidine in an Urban Watershed. [PDF]
Arch Environ Contam Toxicol, 2022 Prompted by a recent report that 6PPD-quinone (6PPD-q), a by-product of a common tire manufacturing additive that is present in road runoff, is toxic to coho salmon (Oncorhynchus kisutch), extracts of water samples collected from an urban river were re-analyzed to determine if this compound was present in stormwater-influenced flows.
Johannessen C +4 more
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6PPD-quinone exposure and Alzheimer’s disease: insights from integrative network pharmacology, transcriptomics, machine learning, and molecular docking [PDF]
Open MedicineTo systematically investigate the molecular associations between 6PPD-quinone (6PPD-Q), an environmental transformation product of the tire antioxidant 6PPD, and Alzheimer’s disease (AD) pathogenesis.
Zhang Chun, Zhang Jingqi
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Comprehensive review on environmental pollution caused by 6PPD-quinone and remediation strategies. [PDF]
RSC AdvThere is ongoing research concerning the environmental toxicity associated with 6PPD ( N -(1,3-dimethylbutyl)- N ′-phenyl- p -phenylenediamine) and its by-products due to tyre wear.
Sivalingam S +4 more
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Correction to "Investigation of 6PPD-Quinone in Rubberized Asphalt Concrete Mixtures". [PDF]
ACS Environ Au[This corrects the article DOI: 10.1021/acsenvironau.3c00023.].
Lokesh S +7 more
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Effects of 6PPD-Quinone on Human Liver Cell Lines as Revealed with Cell Viability Assay and Metabolomics Analysis [PDF]
ToxicsN-(1,3-Dimethyl butyl)-N′-phenyl-phenylenediamine-quinone (6PPD-Q) is a derivative of the widely used rubber tire antioxidant 6PPD, which was first found to be acutely toxic to coho salmon. Subsequent studies showed that 6PPD-Q had species-specific acute
Yunqing Qi +5 more
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