Acute Toxicity Testing of the Tire Rubber–Derived Chemical 6PPD-quinone on Atlantic Salmon (Salmo salar) and Brown Trout (Salmo trutta) [PDF]
Recent identification of 6PPD-quinone as the chemical causing acute toxicity in coho salmon has led to substantial concern regarding toxicity of this contaminant for other aquatic species.
Silvio Uhlig +2 more
exaly +5 more sources
Association between 6PPD-quinone exposure and BMI, influenza, and diarrhea in children [PDF]
N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone (6PPD-quinone) has received extensive attention due to its ubiquitous distribution and potential toxicity. However, the distribution characteristics of 6PPD-quinone in dust from e-waste recycling areas and the consequential health risks to children are unclear.
Xia Huo, Machteld Hylkema
exaly +5 more sources
The pervassive release of tire and road wear particles (TRWPs) introduces the tire additive 6PPD and its biologically active derivative, 6PPD-quinone (6PPD-Q), into the environment, with soil serving as the primary sink. However, at present their fate in
Nathan Sy, Jay Gan, Dahang Shen
exaly +4 more sources
Adverse effects of 6PPD-quinone bioaccumulation at environmentally relevant concentrations on Cyprinus carpio growth and development [PDF]
With industrial advancements, the development and use of various additive substances have increased, leading to their potential release into the environment during use and disposal. As a primary tyre additive, the rubber additive, N1-(4-methylpentan-2-yl)
Yooeun Chae +7 more
doaj +2 more sources
Potential hazard assessment of 6PPD-quinone in the context of ulcerative colitis: network toxicology, machine learning, transcriptomic analysis, and preliminary In vivo validation [PDF]
BackgroundThe ubiquitous tire-derived pollutant 6PPD-quinone (6PPD-Q) poses potential systemic health risks, yet its toxicological impact on the intestinal tract, particularly in the context of ulcerative colitis (UC), remains largely unknown. This study
Jingyi Li +5 more
doaj +2 more sources
Toxicity of ubiquitous tire rubber antiozonant N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its transformation product 6PPD-quinone (6PPD-Q) in primary human hepatocytes and liver spheroids [PDF]
The tire rubber antioxidant N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its oxidation product 6PPD-quinone (6PPD-Q) were recently found in human bodies.
Daniel J. Yeisley +7 more
doaj +2 more sources
Intensive Spatiotemporal Characterization of the Tire Wear Toxin 6PPD Quinone in Urban Waters. [PDF]
6PPDQ is a tire-derived contaminant toxic to coho salmon (LC50 = 41–95 ng/L) found widely distributed in urban environments. Most monitoring efforts have relied on relatively few discrete samples collected at select locations across rain events. Early work has revealed that 6PPDQ concentrations vary widely over time and space, raising questions about ...
Jaeger A +5 more
europepmc +3 more sources
Watershed analysis of urban stormwater contaminant 6PPD-Quinone hotspots and stream concentrations using a process-based ecohydrological model [PDF]
Coho salmon (Oncorhynchus kisutch) are highly sensitive to 6PPD-Quinone (6PPD-Q). Details of the hydrological and biogeochemical processes controlling spatial and temporal dynamics of 6PPD-Q fate and transport from points of deposition to receiving ...
Jonathan J. Halama +17 more
doaj +2 more sources
Advances in Analytical Determination Methods and Toxicity and Health Risk Assessment of 6PPD and Its Transformation Products in Food [PDF]
N-(1,3-Dimethylbutyl)-N’-phenyl-p-phenylenediamine (6PPD) is a member of the p-phenylenediamines (PPDs), recognized as a highly effective antioxidant. It has been extensively employed in the automotive tire manufacturing industry, and plays a critical ...
Bolin Liu +5 more
doaj +2 more sources
N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6PPD-quinone) is an oxidation product of the tire antioxidant 6PPD and has recently emerged as a toxic environmental contaminant.
Hajeong Jeon +3 more
doaj +2 more sources

