Genomic and Phenotypic Characterization of Avian-Derived <i>Limosilactobacillus reuteri</i> Strains Showing Pathogen-Inhibiting Activity and Folate Production. [PDF]
Animals (Basel)Kuniyoshi TM +13 more
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Ligand specificity and adaptability revealed by the first Guanine-II riboswitch tertiary structure. [PDF]
Nucleic Acids ResLi H +6 more
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Synergistic Effects of Auranofin and Lysozyme Against Staphylococcus Aureus. [PDF]
Probiotics Antimicrob ProteinsZhang Q, Yang Y, Li S, Chiou J, Zhao Q.
europepmc +1 more source
Crystal Structure of 7,8-Dihydroneopterin Triphosphate Epimerase [PDF]
Structure, 1999 Dihydroneopterin triphosphate (H2NTP) is the central substrate in the biosynthesis of folate and tetrahydrobiopterin. Folate serves as a cofactor in amino acid and purine biosynthesis and tetrahydrobiopterin is used as a cofactor in amino acid hydroxylation and nitric oxide synthesis.
Adelbert Bacher +2 more
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Modulation of LDL Oxidation by 7,8-Dihydroneopterin
Free Radical Research, 2004Human macrophages stimulated with interferon-gamma generate neopterin and 7,8-dihydroneopterin which interfere with reactive species involved in LDL oxidation. While neopterin was found to have pro-oxidative effects on copper-mediated LDL oxidation, the influence of 7,8-dihydroneopterin is more complex. This study provides detailed information that 7,8-
Gilbert Reibnegger +2 more
exaly +3 more sources
Neopterin and 7,8-Dihydroneopterin Induce Apoptosis in the Rat Alveolar Epithelial Cell Line L2 [PDF]
FEBS Letters, 1996 The neopterin derivatives, neopterin and 7,8‐dihydroneopterin, modulate the cellular oxidant‐antioxidant balance as well as the expression of the inducible nitric oxide synthase (iNOS) gene. Since apoptosis can be induced by reactive oxygen intermediates and nitric oxide (NO) we investigated whether these neopterin derivatives induce apoptotic cell ...
Wolfgang Schobersberger +2 more
exaly +3 more sources
Increased 7,8-Dihydroneopterin and Reduced Methyl-Group Metabolism in HIV-1 Infection
Lancet, The, 1990Gilbert Reibnegger +2 more
exaly +3 more sources
Clinical measurement of neopterin has been extensively used as a marker of inflammation but the in vivo mechanism generating neopterin is poorly understood. Neopterin is described as the oxidation product of 7,8-dihydroneopterin, a potent antioxidant generated by monocyte/macrophages in response to interferon-γ.
Barry Hock +2 more
exaly +4 more sources
Formation of Oxygen Radicals in Solutions of 7,8-Dihydroneopterin
Biochemical and Biophysical Research Communications, 1999Neopterin and 7,8-dihydroneopterin, two compounds which are secreted by activated macrophages, have been shown to interfere with radicals generated by cellular and certain chemical systems. Reduced pterins were reported to scavenge whereas aromatic pterins promoted or reduced radical mediated reactions or had no effect.
K, Oettl +5 more
openaire +2 more sources
Interference of 7,8-dihydroneopterin with peroxynitrite-mediated reactions
Biochemical and Biophysical Research Communications, 2004By in vitro studies 7,8-dihydroneopterin, which is secreted by macrophages stimulated by interferon-gamma, was reported to be a radical scavenger as well as a prooxidative agent depending on the experimental settings. In this study, we investigated the interference of 7,8-dihydroneopterin with peroxynitrite mediated reactions by different analytical ...
Karl, Oettl +3 more
openaire +2 more sources