Results 171 to 179 of about 37,816 (179)

Role of 7,8-dihydroneopterin in T-cell apoptosis and HTLV-1 transcription in vitro.

Oncogene, 1997
Adult T-cell leukemia is associated with high levels of neopterin, released in large amounts from human macrophages upon stimulation with interferon-gamma. Recent data suggested a potential role of neopterin-derivatives in oxygen radical-mediated processes, and evidence accumulates that oxidative stress is involved in the pathogenesis of viral diseases.
G, Baier-Bitterlich, G, Baier, D, Fuchs, G, Böck, A, Hausen, G, Utermann, M, Pavelka, H, Wachter   +7 more
openaire   +1 more source

7,8-Dihydroneopterin-mediated protection of low density lipoprotein, but not human macrophages, from oxidative stress

2006
Any lipoproteins and cells present in the inflammatory environment of atherosclerotic plaques are likely to be exposed to high levels of oxidative stress. As 7,8-dihydroneopterin (7,8-NP) is synthesized by interferon-γ (IFN-γ)-activated macrophages, this pteridine is also thought to exist at sites of inflammation.
openaire   +2 more sources

7,8 Dihydroneopterin inhibits low density lipoprotein oxidation in vitro. Evidence that this macrophage secreted pteridine is an anti-oxidant.

Free radical research, 1995
S. Gieseg, G. Reibnegger, H. Wachter, H. Esterbauer   +3 more
semanticscholar   +1 more source

7,8 dihydroneopterin can protect cells from free radical mediated damage

Free Radical Biology and Medicine, 1998
Steven Gieseg, Tomas Cruz, Dylan Glubb, Ghassan Muzghal, Jacqueline Whybrow   +4 more
openaire   +1 more source

Increased 7,8-dihydroneopterin and reduced methyl-group metabolism in HIV-1 infection

The Lancet, 1990
D, Fuchs, G, Reibnegger, E R, Werner, H, Wachter   +3 more
openaire   +2 more sources

Induction of apoptosis in human blood T cells by 7,8-dihydroneopterin: the difference between healthy controls and patients with systemic lupus erythematosus.

Clinical Immunology, 2003
B. Wirleitner, G. Obermoser, G. Böck, G. Neurauter, H. Schennach, N. Sepp, D. Fuchs   +6 more
semanticscholar   +1 more source

Induction of apoptosis by 7,8-dihydroneopterin: involvement of radical formation.

Immunobiology, 2001
B. Wirleitner, R. Czaputa, K. Oettl, G. Böck, B. Widner, G. Reibnegger, G. Baier, D. Fuchs, G. Baier‐Bitterlich   +8 more
semanticscholar   +1 more source

Inflammation marker 7,8-dihydroneopterin induces apoptosis of neurons and glial cells: a potential contribution to neurodegenerative processes.

Immunobiology, 2000
C. Speth, G. Stöckl, D. Fuchs, B. Wirleitner, B. Widner, R. Würzner, I. Mohsenipour, C. Lass‐Flörl, M. Dierich   +8 more
semanticscholar   +1 more source

7,8-Dihydroneopterin-induced apoptosis in Jurkat T lymphocytes: a comparison with anti-Fas- and hydrogen peroxide-mediated cell death.

Biochemical Pharmacology, 1998
B. Wirleitner, G. Baier‐Bitterlich, G. Böck, B. Widner, D. Fuchs   +4 more
semanticscholar   +1 more source