Results 121 to 130 of about 76,183,421 (152)

Assessing Plasma Stability of 7-Hydroxymitragynine Found in Kratom

Johnson, Elliot, McDougal, Owen, Seiber, Jessica, Reed, Oliver, Shuey, Anna J., Bennett, Fashion   +5 more
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A Review on Multi-Therapeutic Potential of the Mitragyna speciosa (Kratom) Alkaloids Mitragynine and 7-Hydroxymitragynine: Experimental Evidence and Future Perspectives

Kuwait Journal of Science
Mitragyna speciosa (kratom) is a traditional medicinal plant of Southeast Asia, known for its pharmacologically active alkaloids, Mitragynine and 7-hydroxymitragynine.
Syed Najmul Hejaz Azmi, Alfi Khatib
exaly   +4 more sources

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Antinociception, Tolerance and Withdrawal Symptoms Induced by 7-Hydroxymitragynine, an Alkaloid From the Thai Medicinal Herb Mitragyna speciosa

Life Sciences, 2005
7-Hydroxymitragynine is a potent opioid analgesic alkaloid isolated from the Thai medicinal herb Mitragyna speciosa. In the present study, we investigated the opioid receptor subtype responsible for the analgesic effect of this compound. In addition, we tested whether development of tolerance, cross-tolerance to morphine and naloxone-induced withdrawal
Kenjiro Matsumoto, Hayato Ishikawa, Hiromitsu Takayama   +2 more
exaly   +3 more sources

Development, validation, and application of an LC–MS/MS method for mitragynine and 7‐hydroxymitragynine analysis in hair

Drug Testing and Analysis, 2020
AbstractThe entire scalp hair of a self‐declared Kratom consumer of 3 grams per day was acquired during an ethical committee approved study. As no values of the concentration in hair of the two Kratom alkaloids mitragynine or 7‐hydroxymitragynine were found in the literature, an already established method for the analysis of benzodiazepines/z ...
Ulf Meier, Katja Mercer‐Chalmers‐Bender, Eva Scheurer, Franz Dussy   +3 more
openaire   +4 more sources

Postmortem distribution of mitragynine and 7-hydroxymitragynine in 51 cases

Journal of Analytical Toxicology
Abstract The prevalence of mitragynine (kratom) in forensic toxicology casework has steadily increased over time. Readily available and currently legal, mitragynine is widely used for its stimulant and, depending on concentration, sedative effects.
Kei A Osawa, Robert D Johnson
openaire   +2 more sources

Chemistry and Toxicity of 7-Hydroxymitragynine (7-OHMG): An Updated Review on the Oxidized Derivative of Mitragynine

Phytochemistry Reviews
Janar Jenis, U Seeta Uthaya Kumar, Thiruventhan Karunakaran   +2 more
exaly   +2 more sources

A Case of 7-Hydroxymitragynine Use Disorder Treated With Buprenorphine

Journal of Addiction Medicine
Background: Kratom is a plant widely consumed for the stimulant and opioid properties of its primary psychoactive component, mitragynine. A related compound, 7-hydroxymitragynine (7-HMG), also known colloquially as “7-OH,” “7-Hydroxy,” “7-OHMG,” or “7,” is present in kratom in smaller amounts but is much more ...
Reuben Hendler, Zoe Karavolis, Jungjin Kim, Gerardo Gonzalez   +3 more
openaire   +1 more source