Results 1 to 10 of about 1,513 (131)

Mitragyna Species as Pharmacological Agents: From Abuse to Promising Pharmaceutical Products

Life, 2022
Mitragyna is a genus belonging to the Rubiaceae family and is a plant endemic to Asia and Africa. Traditionally, the plants of this genus were used by local people to treat some diseases from generation to generation.
Islamudin Ahmad, Wisnu Cahyo Prabowo, Muhammad Arifuddin, Jaka Fadraersada, Niken Indriyanti, Herman Herman, Reza Yuridian Purwoko, Firzan Nainu, Anton Rahmadi, Swandari Paramita, Hadi Kuncoro, Nur Mita, Angga Cipta Narsa, Fajar Prasetya, Arsyik Ibrahim, Laode Rijai, Gemini Alam, Abdul Mun’im, Sukanya Dej-adisai   +18 more
doaj   +2 more sources

Mitragyna speciosa as a Potential Substitute Therapy in Opioid Dependence: A Case Report

Pharmaceutical Sciences and Research, 2022
Preclinical data have consistently suggested the pharmaceutical potential of kratom (Mitragyna speciosa), including as a substitute therapy in opioid dependence.
Karniza Khalid, Jason S.K. Wong, Ruzita Jamaluddin   +2 more
doaj   +2 more sources

In Vitro and in Vivo Effects of Three Different Mitragyna speciosa Korth Leaf Extracts on Phase II Drug Metabolizing Enzymes—Glutathione Transferases (GSTs)

Molecules, 2010
In the present study, we investigate the effects of three different Mitragyna speciosa extracts, namely methanolic, aqueous and total alkaloid extracts, on glutathione transferase-specific activity in male Sprague Dawley rat liver cytosol in vitro and in
Mohd Nizam Mordi, Juzaili Azizi, Surash Ramanathan   +2 more
exaly   +3 more sources

Precipitated withdrawal with kratom use following naltrexone administration [PDF]

Mental Health Clinician, 2023
Kratom is an herbal supplement with reports of use for natural pain relief or treatment of opioid withdrawal symptoms. Kratom has metabolites that bind to and agonize mu-opioid receptors similar to opiate medications.
Jarka Courtney PharmD, BCPS, BCPP, Gregoire Kelsey PharmD, BCCCP   +1 more
doaj   +1 more source

Differentiation of Mitragyna speciosa, a narcotic plant, from allied Mitragyna species using DNA barcoding-high-resolution melting (Bar-HRM) analysis

Scientific Reports, 2021
Mitragyna speciosa (Korth.) Havil. [MS], or “kratom” in Thai, is the only narcotic species among the four species of Mitragyna in Thailand, which also include Mitragyna diversifolia (Wall. ex G. Don) Havil. [MD], Mitragyna hirsuta Havil.
Chayapol Tungphatthong, Santhosh Kumar J. Urumarudappa, Supita Awachai, Thongchai Sooksawate, Suchada Sukrong   +4 more
doaj   +1 more source

The Mitragyna speciosa (Kratom) Genome: a resource for data-mining potent pharmaceuticals that impact human health

G3: Genes, Genomes, Genetics, 2021
Mitragyna speciosaM.
Julia Brose, Kin H Lau, Thu Thuy Thi Dang, John P Hamilton, Lívia do Vale Martins, Britta Hamberger, Bjoern Hamberger, Jiming Jiang, Sarah E O’Connor, C Robin Buell   +9 more
doaj   +1 more source

Proximate composition and mineral profile of elephants forages in the Savannah ecological zone of Ghana

Journal of Applied Animal Research, 2023
This study evaluated the proximate and mineral composition of various parts of Balanites aegyptiaca, Mitragyna inermis, Cassia sieberiena, Kigelia africana, Detarium microcarpum, Terminalia laxiflora, Ficus platyphylla and Climber plant (Liana) as feeds ...
Sylvenus Aguree, Samson Abah Abagale, Isaac Sackey   +2 more
doaj   +1 more source

A Chromosome-Scale Genome Assembly of Mitragyna speciosa (Kratom) and the Assessment of Its Genetic Diversity in Thailand

Biology, 2022
Mitragyna speciosa (Kratom) is a tropical narcotic plant native to Southeast Asia with unique pharmacological properties. Here, we report the first chromosome-scale assembly of the M. speciosa genome. We employed PacBio sequencing to obtain a preliminary
Wirulda Pootakham, Thippawan Yoocha, Nukoon Jomchai, Wasitthee Kongkachana, Chaiwat Naktang, Chutima Sonthirod, Srimek Chowpongpang, Panyavut Aumpuchin, Sithichoke Tangphatsornruang   +8 more
doaj   +1 more source

Inhibition of Advanced Glycation End-Products by Tamarindus indica and Mitragyna inermis Extracts and Effects on Human Hepatocyte and Fibroblast Viability

Molecules, 2023
Tamarindus indica and Mitragyna inermis are widely used by herbalists to cure diabetes mellitus. The aim of this study is to investigate the inhibitory potential of aqueous and various organic solvent fractions from both plants and some isolated ...
Relwendé Justin Ouédraogo, Umair Aleem, Lassina Ouattara, Muhammad Nadeem-ul-Haque, Georges Anicet Ouédraogo, Humera Jahan, Farzana Shaheen   +6 more
doaj   +1 more source

Flore et écologie de la partie centrale du Bassin de Zio dans un contexte de pression foncière au Togo

Revue Ecosystèmes et Paysages, 2023
Le bassin versant du Zio au Togo est confronté à des défis majeurs tels que l'expansion démographique, l'urbanisation et l'exploitation du bois, entraînant une régression alarmante de sa biodiversité.
Akpegnon Amekaeli Casimir, Abe Akala, Badjare Bilouktime, Folega Fousseni, Kpérkouma Wala, Batawila Komlan, Akpagana Koffi   +6 more
doaj   +1 more source