Results 1 to 10 of about 2,738 (175)

A Chromosome-Scale Genome Assembly of Mitragyna speciosa (Kratom) and the Assessment of Its Genetic Diversity in Thailand [PDF]

Biology, 2022
Mitragyna speciosa (Kratom) is a tropical narcotic plant native to Southeast Asia with unique pharmacological properties. Here, we report the first chromosome-scale assembly of the M. speciosa genome. We employed PacBio sequencing to obtain a preliminary
Wirulda Pootakham, Thippawan Yoocha, Nukoon Jomchai, Wasitthee Kongkachana, Chaiwat Naktang, Chutima Sonthirod, Srimek Chowpongpang, Panyavut Aumpuchin, Sithichoke Tangphatsornruang   +8 more
doaj   +2 more sources

Comparative metabolomics analysis reveals alkaloid repertoires in young and mature Mitragyna speciosa (Korth.) Havil. Leaves. [PDF]

PLoS ONE, 2023
The fresh leaves of Mitragyna speciosa (Korth.) Havil. have been traditionally consumed for centuries in Southeast Asia for its healing properties. Although the alkaloids of M.
Rubashiny Veeramohan, Arief Izzairy Zamani, Kamalrul Azlan Azizan, Hoe-Han Goh, Wan Mohd Aizat, Mohd Fauzi Abd Razak, Nur Sabrina Mohd Yusof, Sharif Mahsufi Mansor, Syarul Nataqain Baharum, Chyan Leong Ng   +9 more
doaj   +2 more sources

Phytochemical profile and chemosensitizing anticancer activity of Mitragyna speciosa and mitragynine [PDF]

Scientific Reports
This study examined the phytochemical composition, antioxidant efficacy, and cytotoxic properties of Mitragyna speciosa (kratom) extracts and its principal alkaloid, mitragynine.
Panita Kongsila, Thidarut Boonmars, Pranee Sriraj, Jatuporn Prathumtet, Praphat Manuelo Ruengthanoo, Ratchadawan Aukkanimart   +5 more
doaj   +2 more sources

Association between kratom (Mitragyna speciosa) use and metabolic syndrome [PDF]

Heliyon, 2022
Background and aims: There are evidence about effects of kratom (Mitragyna speciosa) use on parameters related to metabolic syndrome (MetS). The present study aimed to determine the association between kratom use and MetS.
Aroon La-up, Paleeratana Wongrith, Wiraphon Chaichan, Apinun Aramrattana, Udomsak Saengow   +4 more
doaj   +2 more sources

In Vitro and in Vivo Effects of Three Different Mitragyna speciosa Korth Leaf Extracts on Phase II Drug Metabolizing Enzymes—Glutathione Transferases (GSTs)

Molecules, 2010
In the present study, we investigate the effects of three different Mitragyna speciosa extracts, namely methanolic, aqueous and total alkaloid extracts, on glutathione transferase-specific activity in male Sprague Dawley rat liver cytosol in vitro and in
Juzaili Azizi, Mohd Nizam Mordi, Surash Ramanathan   +2 more
exaly   +3 more sources

Clinical Implications of Kratom (Mitragyna speciosa) Use: a Literature Review [PDF]

Curr Addict Rep, 2023
© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License (CC BY), http://creativecommons.org/licenses/by/4.0/Purpose of Review: This work aims to provide an up-to-date review of the ...
Corazza, Ornella, Esposito, Gianluca, Kuypers, Kim Paula Colette, Pasquini, Massimo, Prevete, Elisabeth, Ramaekers, Johannes Gerardus, Theunissen, Eef Lien   +6 more
core   +4 more sources

Evaluation of Antioxidant and Antibacterial Activities of Aqueous, Methanolic and Alkaloid Extracts from Mitragyna Speciosa (Rubiaceae Family) Leaves

Molecules, 2009
Studies on the antioxidant and antimicrobial activities of Mitragyna speciosa leaf extracts are lacking. In this study the antioxidant properties of water, methanolic and alkaloid M.
Suhanya Parthasarathy, Surash Ramanathan, Sreenivasan Sasidharan   +2 more
exaly   +3 more sources

Mitragyna speciosa Korth toxicity: Experimental findings and future prospects [PDF]

Journal of Taibah University Medical Sciences
الملخص: أهداف البحث: نبات القرطوم، المعروف علميا باسم ميتراجينا سبيسيوزا، هو نبات طبي تقليدي من جنوب شرق آسيا، يحتوي على قلويد الميتراجينين كمركب رئيسي. ومثل النباتات الطبية الأخرى، له آثار جانبية وتأثيرات سمية موثقة في الدراسات العلمية وتقارير الحالات.
Taslima Begum, MSc, Mohd H. Arzmi, PhD, A.B.M. Helal Uddin, PhD, Alfi Khatib, PhD, Syed A. Abbas, PhD, Qamar U. Ahmed, PhD   +5 more
doaj   +2 more sources

Assessment of the possible health risks associated with the consumption of botanical preparations of Mitragyna speciosa (kratom) [PDF]

EFSA Journal, 2022
The current report summarises the work performed in the context of the European Food Risk Assessment Fellowship Programme (EU‐FORA), which included the evaluation of health risks associated with the consumption of botanical preparations of Mitragyna ...
Georgia Papadi, Nadiya Bakhiya, Karen Ildico Hirsch‐Ernst   +2 more
doaj   +2 more sources

DNA Barcoding and Chemical Profile Using UHPLC, GC-MS and LC-MS/QTOF of Mitragyna speciosa Variation and Allied Species for Quality Control of Kratom Materials [PDF]

Plants
Kratom (Mitragyna speciosa Korth.) has gained increasing global attention due to its traditional use, psychoactive properties, and emerging therapeutic potential; however, concerns regarding adulteration, substitution, and inconsistent quality of ...
Phunsuk Anantaworasakul, Warunya Arunotayanun, Siripat Chaichit, Suthiwat Khamnuan, Chatchai Ngernsaengsaruay, Chuda Chittasupho, Nisa Leksungnoen, Mingkwan Na Takuathung, Ruedeemars Yubolphan, Apisada Jiso, Tachpon Techarang, Aekkhaluck Intharuksa   +11 more
doaj   +2 more sources