Results 11 to 20 of about 9,834 (169)

Metabolomics data of Mitragyna speciosa leaf using LC-ESI-TOF-MS

Data in Brief, 2018
Mitragyna speciosa is a psychoactive plant known as “ketum” in Malaysia and “kratom” in Thailand. This plant is distinctly known to produce two important alkaloids, namely mitragynine (MG) and 7-hydroxymitragynine (7-OH-MG) that can bind to opioid ...
Rubashiny Veeramohan, Kamalrul Azlan Azizan, Wan Mohd Aizat, Hoe-Han Goh, Sharif Mahsufi Mansor, Nur Sabrina Mohd Yusof, Syarul Nataqain Baharum, Chyan Leong Ng   +7 more
doaj   +2 more sources

Mitragyna speciosa as a Potential Substitute Therapy in Opioid Dependence: A Case Report [PDF]

Pharmaceutical Sciences and Research, 2022
Preclinical data have consistently suggested the pharmaceutical potential of kratom (Mitragyna speciosa), including as a substitute therapy in opioid dependence.
Karniza Khalid, Jason S.K. Wong, Ruzita Jamaluddin   +2 more
doaj   +3 more sources

Environmental Influence on the Untargeted Foliar Metabolome of Naturally Growing Mitragyna Species in Thailand

Plant-Environment Interactions
This study investigates the foliar secondary metabolite profiles of four Mitragyna species naturally occurring in Thailand: M. diversifolia, M. hirsuta, M. rotundifolia, and M. speciosa (kratom).
Tushar Andriyas, Nisa Leksungnoen, Chatchai Ngernsaengsaruay, Suwimon Uthairatsamee, Rossarin Tansawat, Pakawat Sirilertpanich   +5 more
doaj   +2 more sources

Mitragyna speciosa: Opioid Addiction Treatment and Risk of Use [PDF]

JPSCR: Journal of Pharmaceutical Science and Clinical Research, 2022
Kratom (Mitragyna speciosa (Korth.) Havil.) is a plant that originated from the rainforest in Southeast Asia, mainly grows in Thailand, Malaysia, and Indonesia. Kratom has been used traditionally as an herbal remedy for the treatment of various illnesses.
Azka Muhammad Rusydan, Endang Lukitaningsih, Nanang Fakhrudin   +2 more
doaj   +2 more sources

Antibacterial mechanism of Kratom (Mitragyna speciosa) methanol extract on Streptococcus pneumoniae and Eschericia coli bacteria [PDF]

, 2021
Introduction: Kratom (Mitragyna speciosa) is a tropical herbal plant native to the North Malay Peninsula, Malaysia and Thailand. In Indonesia, kratom us a typical plant of West Kalimantan, especially in Putussibau.
Puspitarini, Marinda Dwi, Salim, Hotimah Masdan, Setiwati, Yuani, Shimabukuro, Michio   +3 more
core   +2 more sources

Antimicrobial Activity of Actinobacteria Isolated From Kratom (<i>Mitragyna speciosa</i>) Leaves: Secondary Metabolite Profiling and Genome Analysis of <i>Micromonospora chersina</i> NRAIS18. [PDF]

Int J Microbiol
Actinobacteria associated with medicinal plants are recognized as prolific sources of novel bioactive compounds. Kratom (Mitragyna speciosa) leaves have been reported to contain a diverse array of secondary metabolites with pharmacological activities, including antibacterial, antioxidant, and anti‐inflammatory effects. In this study, 16 actinobacterial
Pitiwittayakul N, Niyomvong N, Tedsree N, Tanasupawat S.   +3 more
europepmc   +2 more sources

The Mitragyna speciosa (Kratom) Genome: a resource for data-mining potent pharmaceuticals that impact human health

G3: Genes, Genomes, Genetics, 2021
Mitragyna speciosaM.
Julia Brose, Kin H Lau, Thu Thuy Thi Dang, John P Hamilton, Lívia do Vale Martins, Britta Hamberger, Bjoern Hamberger, Jiming Jiang, Sarah E O’Connor, C Robin Buell   +9 more
doaj   +1 more source

Differentiation of Mitragyna speciosa, a narcotic plant, from allied Mitragyna species using DNA barcoding-high-resolution melting (Bar-HRM) analysis

Scientific Reports, 2021
Mitragyna speciosa (Korth.) Havil. [MS], or “kratom” in Thai, is the only narcotic species among the four species of Mitragyna in Thailand, which also include Mitragyna diversifolia (Wall. ex G. Don) Havil. [MD], Mitragyna hirsuta Havil.
Chayapol Tungphatthong, Santhosh Kumar J. Urumarudappa, Supita Awachai, Thongchai Sooksawate, Suchada Sukrong   +4 more
doaj   +1 more source

Mitragyna Species as Pharmacological Agents: From Abuse to Promising Pharmaceutical Products

Life, 2022
Mitragyna is a genus belonging to the Rubiaceae family and is a plant endemic to Asia and Africa. Traditionally, the plants of this genus were used by local people to treat some diseases from generation to generation.
Islamudin Ahmad, Wisnu Cahyo Prabowo, Muhammad Arifuddin, Jaka Fadraersada, Niken Indriyanti, Herman Herman, Reza Yuridian Purwoko, Firzan Nainu, Anton Rahmadi, Swandari Paramita, Hadi Kuncoro, Nur Mita, Angga Cipta Narsa, Fajar Prasetya, Arsyik Ibrahim, Laode Rijai, Gemini Alam, Abdul Mun’im, Sukanya Dej-adisai   +18 more
doaj   +1 more source

Total Synthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites**

Angewandte Chemie, Volume 135, Issue 35, August 28, 2023., 2023
Although opioids have been used in the treatment of pain for centuries, they cause various adverse effects and addiction. Recently, kratom alkaloids emerged as promising analgesic alternatives for pain management with considerably fewer side effects. The first scalable total synthesis of mitragynine pseudoindoxyl, the most potent atypical opioid kratom
Péter Angyal, Kristóf Hegedüs, Bence Balázs Mészáros, János Daru, Ádám Dudás, Anna Rita Galambos, Nariman Essmat, Mahmoud Al‐Khrasani, Szilárd Varga, Tibor Soós   +9 more
wiley   +2 more sources