Results 31 to 40 of about 1,513 (131)
A review on Mitragyna alkaloids pharmacology, biosynthesis and biotechnological insights
Journal of Genetic Engineering and BiotechnologyMitragyna species, known for their diverse traditional uses across various Asian countries, have gained scientific interest due to their pharmacological properties and rich phytochemical composition.
Karma Sherub Wangmo +4 more
doaj +1 more source
Association between kratom (Mitragyna speciosa) use and metabolic syndrome
Heliyon, 2022 Background and aims: There are evidence about effects of kratom (Mitragyna speciosa) use on parameters related to metabolic syndrome (MetS). The present study aimed to determine the association between kratom use and MetS.
Aroon La-up +4 more
doaj +1 more source
Journal of Cutaneous Pathology, Volume 53, Issue 10, Page 887-892, October 2026.ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua +4 more
wiley +1 more source
The alkaloids of the leaves of Mitragyna inermis (Willd.) O. Kuntze
, 1969 The leaves of Mitragyna inermis (Willd.) O. Kuntze have been examined for alkaloids and shown to contain routundifoline, isorotundifoline, rhynchophylline, isorhynchophylline, ciliaphylline, rhynchociline, speciophylline, a small amount of uncarine F ...
E J Shellard, K Sarpong
core +1 more source
Molecules, 2009 Studies on the antioxidant and antimicrobial activities of Mitragyna speciosa leaf extracts are lacking. In this study the antioxidant properties of water, methanolic and alkaloid M.
Mohd I. Mohd. Said +6 more
doaj +1 more source
Food Frontiers, Volume 7, Issue 5, September 2026.Fig leaves represent an underutilized source of bioactive compounds and promising functional ingredients. Emerging extraction technologies offer powerful tools to unlock their potential through sustainable and circular valorization, while addressing key safety and regulatory considerations.
Tamara Cilia Attard +4 more
wiley +1 more source
EduChemia, 2023 Kratom leaves are known as traditional medicine with various benefits, such as antibacterial, antimicrobial, and antioxidant properties. These benefits are attributed to the presence of secondary metabolites, particularly mitragynine.
Syrifah Nur Intan Mutiara +4 more
doaj +1 more source
Medications That Regulate Pregnane X Receptor: A Systematic Review of Current Evidence
Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.PRISMA 2020 flow diagram of study selection for this systematic review of medications that regulate the pregnane X receptor (PXR), from 12 236 records screened to 101 included studies. ABSTRACT The pregnane X receptor (PXR) gene encodes a ligand‐activated protein involved with the metabolism and excretion of drugs, toxins, and other xenobiotics.
Petra Czarniak +4 more
wiley +1 more source
Drug Testing and Analysis, Volume 18, Issue 7, Page 922-932, July 2026.In a randomized, double‐blind, placebo‐controlled study of oral dried kratom leaf powder in healthy kratom‐naive adults, no participants met the clinically meaningful opioid withdrawal threshold; abuse‐related treatment‐emergent adverse events occurred more frequently at higher doses but were generally mild and resolved without sequelae; and no serious
Marion Coe +5 more
wiley +1 more source
European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.This work describes the synthesis of lactose‐ and glucose‐derived chiral ligands and their application in the catalytic enantioselective Friedel–Crafts alkylation of indole with a series of trans‐β‐nitrostyrenes. The optimal ligand was an acetate protected, lactose‐derived pyridyl imine and its zinc complex afforded ees up to 93% and yields up to 93 ...
Sandra Bulawa +2 more
wiley +1 more source