7‑hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects [PDF]
Mitragynina speciosa, more commonly known as kratom, is a plant native to Southeast Asia, the leaves of which have been used traditionally as a stimulant, analgesic, and treatment for opioid addiction.
Ansonoff, Michael +12 more
core +3 more sources
Kratom use disorder as a gateway to an opioid use disorder
Introduction Kratom (Mitragyna speciosa) is a psychoactive substance native to Thailand and Southeast Asia with stimulant-like effects at lower doses and opioid-like effects at higher doses.
A. C. Borges, D. Machado
doaj +1 more source
Agro-waste: a potential fermentation substrate for Penicillium chrysogenum [PDF]
Common agro-wastes found in Lagos, Nigeria (cassava shavings, corncob, sawdust, and sugarcane pulp) were compared with glucose and lactose as fermentation substrates for Penicillium chrysogenum PCL501.
Chinedu, S. N. +3 more
core +2 more sources
New Metabolites From the Endophytic Fungus Associated With
Two new natural products, mitrafungidione (1) elucidated as prototrop-isomers of ( R -3-acetyl-5-ethyl-4-hydroxy-5 H -furan-2-one, and maristachone F (2a), elucidated as 5-(1-hydroxyethyl)-4-(hydroxymethyl)-3-methoxy-2-methylphenol, together with 5 known
Erik Donfack Vouffo +6 more
doaj +1 more source
Changing Trends in the Use of Kratom (Mitragyna speciosa) in Southeast Asia [PDF]
This is the pre-peer reviewed version of the following article: Darshan Singh, Suresh Narayanan, Balasingam Vicknasingam, Ornella Corazza, Rita Santacroce, and Andres Roman-Urrestarazu, ‘Changing trends in the use of kratom (Mitragyna speciosa) in ...
Corazza, Ornella +5 more
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Tree Species Composition and Forest Stratification along the Gradients in the Dry Deciduous Forests of Godavari Valley, Telangana, India [PDF]
It is important to understand the tree species composition, abundance, species diversity and stratification in tropical dry deciduous forests that are under threat. A quadrat study was attempted in the dry deciduous forests along the ecological
Raju, Vatsavaya S, Suthari, Sateesh
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Biochemical Benefits, Diagnosis, and Clinical Risks Evaluation of Kratom
BackgroundKratom (Mitragyna speciosa) is a tropical tree with a long history of traditional use in parts of Africa and Southeast Asia. Kratom is also known as Thom, Thang, and Biak.
Dimy Fluyau, Neelambika Revadigar
doaj +1 more source
Evaluation of the cardiotoxicity of mitragynine and its analogues using human induced pluripotent stem cell-derived cardiomyocytes. [PDF]
INTRODUCTION:Mitragynine is a major bioactive compound of Kratom, which is derived from the leave extracts of Mitragyna speciosa Korth or Mitragyna speciosa (M. speciosa), a medicinal plant from South East Asia used legally in many countries as stimulant
Jun Lu +7 more
doaj +1 more source
Metabolomics data of Mitragyna speciosa leaf using LC-ESI-TOF-MS
Mitragyna speciosa is a psychoactive plant known as “ketum” in Malaysia and “kratom” in Thailand. This plant is distinctly known to produce two important alkaloids, namely mitragynine (MG) and 7-hydroxymitragynine (7-OH-MG) that can bind to opioid ...
Rubashiny Veeramohan +7 more
doaj +1 more source
Association between kratom (Mitragyna speciosa) use and metabolic syndrome
Background and aims: There are evidence about effects of kratom (Mitragyna speciosa) use on parameters related to metabolic syndrome (MetS). The present study aimed to determine the association between kratom use and MetS.
Aroon La-up +4 more
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