Results 101 to 110 of about 4,015 (203)

Low and heterogeneous prevalence of glucose-6-phosphate dehydrogenase deficiency in different settings in Ethiopia using phenotyping and genotyping approaches

Malaria Journal, 2018
Background 8-Aminoquinolines such as primaquine clear mature Plasmodium falciparum gametocytes that are responsible for transmission from human to mosquitoes and bring radical cure in Plasmodium vivax by clearing dormant liver stages.
Getasew Shitaye, Endalamaw Gadisa, Lynn Grignard, Girma Shumie, Wakweya Chali, Temesgen Menberu, Mulualem Belachew, Getaneh Tegegn, Sagni Challi, Jonathan Curry, Laleta Mahey, Tsegaye Hailu, Hassen Mamo, Menakath Menon, Taye Balcha, Abraham Aseffa, Chris Drakeley, Teun Bousema, Fitsum G. Tadesse   +18 more
doaj   +1 more source

Prevalence of glucose-6-phosphate dehydrogenase deficiency (G6PDd), CareStart qualitative rapid diagnostic test performance, and genetic variants in two malaria-endemic areas in Sudan

PLoS Neglected Tropical Diseases, 2021
Glucose-6-phosphate dehydrogenase deficiency (G6PDd) is the most common enzymopathy globally, and deficient individuals may experience severe hemolysis following treatment with 8-aminoquinolines.
Musab M. Ali Albsheer, Andrew A. Lover, Sara B. Eltom, Leena Omereltinai, Nouh Mohamed, Mohamed S. Muneer, Abdelrahim O. Mohamad, Muzamil Mahdi Abdel Hamid   +7 more
doaj  

Chimiothérapie des theilérioses bovines par un anticoccidien, l'halofuginone : note préliminaire [PDF]

, 1980
L'anticoccidien halofuginone est un schizonticide puissant contre Theileria parva, agent de la fièvre de la Côte Est et de la Corridor disease des bovins en Afrique.
Franssen, F.F.J., Jongejan, Frans, Perié, N.M., Uilenberg, Gerrit   +3 more
core  

Bead-based assays to simultaneously detect multiple human inherited blood disorders associated with malaria

Malaria Journal, 2019
Background Glucose-6-phosphate dehydrogenase deficiency (G6PDd), haemoglobin C (HbC) and S (HbS) are inherited blood disorders (IBD) common in populations in malaria endemic areas.
Lynn Grignard, Catherine Mair, Jonathan Curry, Laleta Mahey, Guide J. H. Bastiaens, Alfred B. Tiono, Joseph Okebe, Sam A. Coulibaly, Bronner P. Gonçalves, Muna Affara, Alphonse Ouédraogo, Edith C. Bougouma, Guillaume S. Sanou, Issa Nébié, Kjerstin H. W. Lanke, Sodiomon B. Sirima, Umberto d’Alessandro, Taane G. Clark, Susana Campino, Teun Bousema, Chris Drakeley   +20 more
doaj   +1 more source

HIGHLIGTHS IN 1,2,3-DITHIAZOLE CHEMISTRY [PDF]

, 2010
Among the five-membered heterocycles containing nitrogen and sulphur atoms, 1,2,3-dithiazoles are important compounds due to their unusual physical properties, biological activity and versatile chemistry.
Emmanuel Deau, Hervé Rouillard, Hélène Laborie, Jean-René Chérouvrier, Lisianne Domon, Philippe Pineau, Valérie Thiéry   +6 more
core  

8-Aminoquinolines from Walter Reed Army Institute for Research for treatment and prophylaxis of Pneumocystis pneumonia in rat models. [PDF]

, 1991
Three 8-aminoquinolines from the Walter Reed Army Institute for Research (WRAIR), WR6026, WR238605, and WR242511, strongly inhibited Pneumocystis carinii growth in vitro at 1 microgram/ml. This activity was similar to that of primaquine.
Bartlett, M. S., Queener, S. F., Tidwell, R. R., Milhous, W. K., Berman, J. D., Ellis, W. Y., Smith, J. W.   +6 more
core   +2 more sources

Prevalence and distribution of glucose-6-phosphate dehydrogenase (G6PD) variants in Thai and Burmese populations in malaria endemic areas of Thailand

Malaria Journal, 2011
Background G6PD deficiency is common in malaria endemic regions and is estimated to affect more than 400 million people worldwide. Treatment of malaria patients with the anti-malarial drug primaquine or other 8-aminoquinolines may be associated with ...
Phompradit Papichaya, Kuesap Jiraporn, Chaijaroenkul Wanna, Rueangweerayut Ronnatrai, Hongkaew Yaowaluck, Yamnuan Rujira, Na-Bangchang Kesara   +6 more
doaj   +1 more source

Genotypic and phenotypic characterization of G6PD deficiency in Bengali adults with severe and uncomplicated malaria

Malaria Journal, 2017
Background Control of malaria increasingly involves administration of 8-aminoquinolines, with accompanying risk of haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Katherine Plewes, Ingfar Soontarawirat, Aniruddha Ghose, Germana Bancone, Hugh W. F. Kingston, M. Trent Herdman, Stije J. Leopold, Haruhiko Ishioka, Md. Abul Faiz, Nicholas M. Anstey, Nicholas P. J. Day, Md. Amir Hossain, Mallika Imwong, Arjen M. Dondorp, Charles J. Woodrow   +14 more
doaj   +1 more source

Pharmacology of 8-aminoquinolines.

Bulletin of the World Health Organization, 1982
The 8-aminoquinolines were the first group of compounds to be synthesized specifically for their antimalarial activity. A large-scale research programme in the United States of America in the 1940s produced three new antimalarial drugs-pentaquine, isopentaquine, and primaquine -of which primaquine was the most effective.
openaire   +1 more source

Recent Advances in the Treatment of Malaria

Pharmaceutics
Malaria is still one of the major global health challenges affecting millions annually, particularly in non-Mediterranean Africa and Southeast Asia. Over the past two decades, substantial progress has been made in reducing malaria-related morbidity and ...
Jawaher M. Alghamdi, Arwa A. Al-Qahtani, Fatimah S. Alhamlan, Ahmed A. Al-Qahtani   +3 more
doaj   +1 more source