Results 81 to 90 of about 1,092 (179)
ABSTRACT Background G6PD deficiency affects about 500 million people worldwide and is prevalent in many malaria‐endemic settings. People with G6PD deficiency are at risk of hemolysis when exposed to certain medications, including 8‐aminoquinoline drugs used to treat Plasmodium vivax malaria.
Flavia Regina Medeiros da Silva +7 more
wiley +1 more source
BackgroundGlucose-6-phosphate dehydrogenase (G6PD) deficiency is a common enzyme deficiency, prevalent in many malaria-endemic countries. G6PD-deficient individuals are susceptible to hemolysis during oxidative stress, which can occur from exposure to ...
Stephanie Zobrist +14 more
doaj +1 more source
History of malaria treatment as a predictor of subsequent subclinical parasitaemia: A cross-sectional survey and malaria case records from three villages in Pailin, western Cambodia [PDF]
Background: Treatment of the sub-clinical reservoir of malaria, which may maintain transmission, could be an important component of elimination strategies.
Chalk, J. (Jeremy) +16 more
core +1 more source
Favism, that is G6PD deficiency, and drugs for Covid-19 [PDF]
A document, vital for people having Glucose-6-phosphate dehydrogenase deficiency (favism) is available. The link is https://www.epicentro.iss.it/coronavirus/pdf/en-report-covid-19-14-2020.pdf .
Amelia Carolina Sparavigna
core +2 more sources
Synthetic Studies Towards Darobactin A
The urgent need for new antibiotics led us to develop a new methodology for the synthesis of the natural product darobactin A selectively targeting gram‐negative bacteria. This study provides new insights into the synthesis of strained indole‐containing macrocycles.
Till Steiner +4 more
wiley +1 more source
Molecular and immunological analyses of confirmed Plasmodium vivax relapse episodes
Background Relapse infections resulting from the activation hypnozoites produced by Plasmodium vivax and Plasmodium ovale represent an important obstacle to the successful control of these species.
Sarunya Maneerattanasak +9 more
doaj +1 more source
Recent advances using [Cp*Co(CO)I2] catalysts as a powerful tool for C-H functionalisation [PDF]
Expansion of the synthetic chemists' toolbox is currently a topic of great interest, with successes providing access to novel compounds and more efficient routes towards new and known pharmaceuticals and agrochemicals.
Chirila, Paula G, Whiteoak, Christopher
core +1 more source
Metabolism of Various 8-Aminoquinolines in Rhesus Monkey.
SummaryStudies on the metabolism of the 8-aminoquinolines, pamaquine, isopentaquine, primaquine, pentaquine, SN 13,058, and CN 1100, have been carried out in the rhesus monkey. As shown by differential analyses of the 8-aminoquinoline contents of plasma, each of the above compounds is degraded to alkali-soluble, ethylene dichloride-insoluble ...
H B, BUGHES, L H, SCHMIDT
openaire +2 more sources
The computation of the photophysical properties of the Mn(I) fac‐[MnBr(CO)3(AQ)] photoCORM shows how different solvents can influence structural and light‐triggered behavior for CO molecules release, very likely occurring from triplet states with MC character.
Daniele Belletto +5 more
wiley +1 more source
Plant-derived antimalarial agents: from crude extracts to isolated bioactive compounds [PDF]
Despite decades of intense research, malaria remains a deadly disease of the developing worlds. Drugresistance to limited available antimalarials, in part, has contributed to the persistence of this infectious disease.
Abdullah, Wan Omar, Ismail, Patimah
core

