Results 121 to 130 of about 1,092 (179)
Cytostatic cytocidal profiling of quinoline drug combinations via modified fixed-ratio isobologram analysis [PDF]
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Reactions of 8-Aminoquinoline with Diorganotin Dichlorides. [PDF]
Annemette Bengtson +10 more
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3D QSAR, pharmacophore and molecular docking studies of known inhibitors and designing of novel inhibitors for M18 aspartyl aminopeptidase of [PDF]
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8-Aminoquinolines as anticoccidials — II
Bioorganic & Medicinal Chemistry Letters, 1998During a chemistry program aimed at finding a novel analogue of pentaquine with improved in vivo activity, a number of hypotheses concerning the way this drug acts in the chicken were investigated. Consideration of the products of monoamine oxidase metabolism of pentaquine suggested that pentaquine aldehyde is the likely active metabolite.
R E, Armer +8 more
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8-aminoquinolines as anticoccidials - part III
Bioorganic & Medicinal Chemistry Letters, 1999Analogues of the antimalarial pentaquine, 1, in which the nature of the side-chain on the 8-amino position was varied, were prepared and evaluated for anticoccidial activity both in vitro and in vivo. Specifically, both the inter-nitrogen distance and the nature of the terminal amino group were investigated.
R E, Armer +10 more
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8-Aminoquinolines: future role as antiprotozoal drugs
Current Opinion in Infectious Diseases, 2006This review focuses on recent developments on evaluation of 8-aminoquinoline analogs with broader efficacy and reduced toxicity, which would provide better drugs for treatment of protozoal infections.The earlier efforts towards development of 8-aminoquinoline analogs have been directed to extensive derivatization programs.
Babu L, Tekwani, Larry A, Walker
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Thermochimica Acta, 1994
Abstract Tin(IV) complexes with 8-aminoquinoline (complexes (1) and (2)) and with salicylidene-8-aminoquinoline (complex (3)) have been prepared and characterized. Complexes (1) and (3) are thermochromic, and display irreversible and reversible thermochromism, respectively.
Ahmed M. Donia, Hanaa El-Boraey
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Abstract Tin(IV) complexes with 8-aminoquinoline (complexes (1) and (2)) and with salicylidene-8-aminoquinoline (complex (3)) have been prepared and characterized. Complexes (1) and (3) are thermochromic, and display irreversible and reversible thermochromism, respectively.
Ahmed M. Donia, Hanaa El-Boraey
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Electrochemistry of ruthenium(ii) complexes of 8-aminoquinoline
Dalton Transactions, 2009Oxidation of [Ru(NH(2)Q)(3)](2+) (NH(2)Q = 8-aminoquinoline) results in intermolecular coupling of 8-aminoquinoline ligands to yield an electroactive polymer. Oxidative polymerization is not observed for [Ru(bpy)(2)(NH(2)Q)](2+) (bpy = 2,2'-bipyridine), where only one 8-aminoquinoline ligand is present.
Megan K, O'Neill +4 more
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Fluorescence and phosphorescence of 5- and 8-aminoquinoline
Analytica Chimica Acta, 1971Abstract 5-Aminoquinoline and 8-aminoquinoline fluoresce moderately to weakly in low dielectric media but not in strongly hydrogen-bonding or acidic aqueous media. At low temperatures and in rigid media moderately intense fluorescence is observed in aqueous, media at all pH values.
S G, Schulman, L B, Sanders
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Remote C–H Functionalization of 8-Aminoquinoline Ring
Topics in Current Chemistry, 20208-Aminoquinoline is a common nitrogen-containing heterocyclic framework in many natural products, functional materials and useful drugs. It has been developed as a powerful bidentate directing group or ligand auxiliary in the field of C-H bond activation/functionalization in recent years.
Zhihui Xu +3 more
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