Results 111 to 120 of about 1,092 (179)

SYNTHESIS OF 8-AMINOQUINOLINES. PART VIII

, 1958
Synthesis of 7-chloro-8- (I'-methyl-4'-diethylaminobatyl)-aminoquinoline has been described.
A. RAYCHAUDHURY, ARUN BOSE, U. P. BASU
openaire   +1 more source

HIGHLIGTHS IN 1,2,3-DITHIAZOLE CHEMISTRY [PDF]

, 2010
Among the five-membered heterocycles containing nitrogen and sulphur atoms, 1,2,3-dithiazoles are important compounds due to their unusual physical properties, biological activity and versatile chemistry.
Emmanuel Deau, Hervé Rouillard, Hélène Laborie, Jean-René Chérouvrier, Lisianne Domon, Philippe Pineau, Valérie Thiéry   +6 more
core  

Primaquine in glucose-6-phosphate dehydrogenase deficiency: an adaptive pharmacometric assessment of ascending dose regimens in healthy volunteers

eLife
Background: Primaquine is an 8-aminoquinoline antimalarial. It is the only widely available treatment to prevent relapses of Plasmodium vivax malaria. The 8-aminoquinolines cause dose-dependent haemolysis in glucose-6-phosphate dehydrogenase deficiency ...
Sasithon Pukrittayakamee, Podjanee Jittamala, James A Watson, Borimas Hanboonkunupakarn, Pawanrat Leungsinsiri, Kittiyod Poovorawan, Kesinee Chotivanich, Germana Bancone, Cindy S Chu, Mallika Imwong, Nicholas PJ Day, Walter RJ Taylor, Nicholas J White   +12 more
doaj   +1 more source

Prevalence and distribution of G6PD deficiency: implication for the use of primaquine in malaria treatment in Ethiopia. [PDF]

, 2019
BackgroundG6PD enzyme deficiency is a common enzymatic X-linked disorder. Deficiency of the G6PD enzyme can cause free radical-mediated oxidative damage to red blood cells, leading to premature haemolysis.
Koepfli, Cristian, Lee, Ming-Chieh, Lo, Eugenia, Pestana, Kareen, Raya, Beka, Yan, Guiyun, Yewhalaw, Delenasaw, Zhong, Daibin   +7 more
core  

Design and synthesis of novel ferrocene-quinoline conjugates and evaluation of their electrochemical and antiplasmodium properties [PDF]

, 2020
Chibale, Kelly, Combrinck, Jill, D'hooghe, Matthias, Minić, Aleksandra, Smith, Peter J., Van de Walle, Tim, Van Hecke, Kristof   +6 more
core   +1 more source

Tinjauan Hasil Uji Coba Pengobatan Dan Pencegahan Malaria Di Beberapa Tempat Indonesia, 1986- 1995 [PDF]

, 1997
In Indonesia, only antimalarials chloroquine, sulfadoxine/ sulfalene-pyrimethamine, quinine, and primaquine are available. The development of chloroquine and multidrug resistance poses a therapeutic challenge.
Tjitra, E. (Emiliana)
core  

Optimal balance of benefit versus risk for tafenoquine in the treatment of Plasmodium vivax malaria

Malaria Journal
A single 300 mg dose of tafenoquine (an 8-aminoquinoline), in combination with a standard 3-day course of chloroquine, is approved in several countries for the radical cure (prevention of relapse) of Plasmodium vivax malaria in patients aged ≥ 16 years ...
Raman Sharma, Hema Sharma, Siôn Jones, Isabelle Borghini-Fuhrer, Gonzalo J. Domingo, Rachel A. Gibson, Katie Rolfe, Lionel Tan, Ioana Gabriela Fiţa, Chao Chen, Panayota Bird, Anup Pingle, Stephan Duparc   +12 more
doaj   +1 more source

Epidemiología y tratamiento de Plasmodium vivax = The epidemiology and treatment of Plasmodium vivax [PDF]

, 2014
[spa] La carga de enfermedad y las muertes relacionadas con la malaria han disminuido a nivel global, principalmente gracias a las mejoras en la implementación de las intervenciones para prevenir y tratar la malaria, y en particular al uso de las ...
Betuela, Inoni
core   +1 more source

Metabolism of 8-aminoquinoline antimalarial agents.

Bulletin of the World Health Organization, 1982
Some of the most effective antimalarial agents are derivatives of 8-aminoquinoline. The metabolic products of many of these compounds appear to be toxic to the erythrocytes of certain human subjects, especially those deficient in glucose-6-phosphate dehydrogenase.
A, Strother, I M, Fraser, R, Allahyari, B E, Tilton   +3 more
openaire   +1 more source

Reactions between 8-aminoquinoline and metal ions and volumetric determination of 8-aminoquinoline

BUNSEKI KAGAKU, 1970
Katsumi YAMAMOTO, Yasutoshi NODA
openaire   +2 more sources