Results 111 to 120 of about 4,015 (203)

Malaria and the traveller [PDF]

, 2005
Malaria has reached epidemic proportions. About 40% of the world’s population live in malarious areas. It is estimated that 400 million people are infected by malaria each year and of these, 1-3 million die, mostly children under five years of age.
Tonna, Antonella, Tonna, Ivan
core  

SYNTHESIS OF 8-AMINOQUINOLINES. PART VIII

, 1958
Synthesis of 7-chloro-8- (I'-methyl-4'-diethylaminobatyl)-aminoquinoline has been described.
A. RAYCHAUDHURY, ARUN BOSE, U. P. BASU
openaire   +1 more source

Production and characterization of different types of malaria pigment (hemozoin) and their potential use for screening for hemozoin inhibiting drugs [PDF]

, 2012
Tese de mestrado. Biologia (Microbiologia Aplicada). Universidade de Lisboa, Faculdade de Ciências, 2012Malarial pigment, hemozoin, appears to modulate the immune system, however it remains controversial if it has stimulatory or inhibitory effects ...
Góis, Ana Margarida Ferreira, 1988-
core  

Primaquine in glucose-6-phosphate dehydrogenase deficiency: an adaptive pharmacometric assessment of ascending dose regimens in healthy volunteers

eLife
Background: Primaquine is an 8-aminoquinoline antimalarial. It is the only widely available treatment to prevent relapses of Plasmodium vivax malaria. The 8-aminoquinolines cause dose-dependent haemolysis in glucose-6-phosphate dehydrogenase deficiency ...
Sasithon Pukrittayakamee, Podjanee Jittamala, James A Watson, Borimas Hanboonkunupakarn, Pawanrat Leungsinsiri, Kittiyod Poovorawan, Kesinee Chotivanich, Germana Bancone, Cindy S Chu, Mallika Imwong, Nicholas PJ Day, Walter RJ Taylor, Nicholas J White   +12 more
doaj   +1 more source

Prevalence and distribution of G6PD deficiency: implication for the use of primaquine in malaria treatment in Ethiopia. [PDF]

, 2019
BackgroundG6PD enzyme deficiency is a common enzymatic X-linked disorder. Deficiency of the G6PD enzyme can cause free radical-mediated oxidative damage to red blood cells, leading to premature haemolysis.
Koepfli, Cristian, Lee, Ming-Chieh, Lo, Eugenia, Pestana, Kareen, Raya, Beka, Yan, Guiyun, Yewhalaw, Delenasaw, Zhong, Daibin   +7 more
core  

R12. Preparation and characterization of ligand attached new 8-aminoquinoline derivative loaded nanostructured lipid carriers for liver targeting [PDF]

, 2020
Corresponding author (Pharmaceutics and Drug delivery): Samir Senapati, ssenapat@go.olemiss.eduhttps://egrove.olemiss.edu/pharm_annual_posters/1011/thumbnail ...
Dudhipala, Narendar, Majumdar, Soumyajit, Mehraj, Tabish, Senapati, Samir   +3 more
core   +1 more source

Tinjauan Hasil Uji Coba Pengobatan Dan Pencegahan Malaria Di Beberapa Tempat Indonesia, 1986- 1995 [PDF]

, 1997
In Indonesia, only antimalarials chloroquine, sulfadoxine/ sulfalene-pyrimethamine, quinine, and primaquine are available. The development of chloroquine and multidrug resistance poses a therapeutic challenge.
Tjitra, E. (Emiliana)
core  

Metabolism of 8-aminoquinoline antimalarial agents.

Bulletin of the World Health Organization, 1982
Some of the most effective antimalarial agents are derivatives of 8-aminoquinoline. The metabolic products of many of these compounds appear to be toxic to the erythrocytes of certain human subjects, especially those deficient in glucose-6-phosphate dehydrogenase.
A, Strother, I M, Fraser, R, Allahyari, B E, Tilton   +3 more
openaire   +1 more source

Primaquine or other 8-aminoquinolines for reducing Plasmodium falciparum transmission. [PDF]

Cochrane Database Syst Rev, 2018
Graves PM, Choi L, Gelband H, Garner P.
europepmc   +1 more source

Phosphothreonine as a catalytic residue in peptide-mediated asymmetric transfer hydrogenations of 8-aminoquinolines. [PDF]

Angew Chem Int Ed Engl, 2015
Shugrue CR, Miller SJ.
europepmc   +1 more source