Results 51 to 60 of about 19,757 (228)

Synthesis, antibacterial properties and bioinformatics computational analyses of novel 8-hydroxyquinoline derivatives

Heliyon, 2019
New heterocyclic derivatives of 8-hydroxyquinoline were prepared and screened as antimicrobial agents. Chemical structures were elucidated and confirmed using different spectroscopic methods such as elemental analysis data, Infrared, Nuclear Magnetic ...
Mohamed Rbaa, Siham Jabli, Younes Lakhrissi, Mohamed Ouhssine, Faisal Almalki, Taibi Ben Hadda, Saida Messgo-Moumene, Abbelkader Zarrouk, Brahim Lakhrissi   +8 more
doaj   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Highlights of the chemistry and pharmacological potential of 8-hydroxyquinoline: a review

Discover Chemistry
Fundamental heterocyclic molecules, quinolone and its analogs, especially 8-hydroxyquinoline, play a significant role in chemical synthesis. It has become clear that 8-hydroxyquinoline derivatives are incredibly adaptable molecules with a wide range of ...
Lian Ojotule Abah, Samuel Attah Egu, Aminu Omale, Simon Sani Ocholi, Jamila Audu Omale, Andrew Omachoko Onoja, Suleiman Kazeem, Abdullahi Abdulrazak, Clifford Baba Okpanachi, Emmanuel Amlabu   +9 more
doaj   +1 more source

No Charging but Protection: Lifetime Prolongation of Spontaneously‐polarized Electrets for Energy Harvesting Applications

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A bilayer protection approach is proposed for slowing down the surface potential decay of thin films of spontaneously‐polarized electret materials. The electret and the protective films are characterized, and the protection effectiveness is investigated under the effects of light illumination, water contact and mechanical impact.
Seyedali Sabzpoushan, Henry Juncker, Peter Woias   +2 more
wiley   +1 more source

Dihydropyrimidine-thiones and clioquinol synergize to target beta-amyloid cellular pathologies through a metal-dependent mechanism [PDF]

, 2017
The lack of therapies for neurodegenerative diseases arises from our incomplete understanding of their underlying cellular toxicities and the limited number of predictive model systems.
Barrasa, M. Inmaculada, Brown, Lauren E., Caldwell, Guy A., Caldwell, Kim A., Jui, Nathan T., Lindquist, Susan, Schaus, Scott E., Tardiff, Daniel F., Trilles, Richard, Yan, Xiaohui   +9 more
core   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

Low-Dimensional Compounds Containing Bioactive Ligands. Part XIX: Crystal Structures and Biological Properties of Copper Complexes with Halogen and Nitro Derivatives of 8-Hydroxyquinoline

Inorganics, 2022
Six new copper(II) complexes were prepared: [Cu(ClBrQ)2] (1a, 1b), [Cu(ClBrQ)2]·1/2 diox (2) (diox = 1,4-dioxane), [Cu(BrQ)2] (3), [Cu(dNQ)2] (4), [Cu(dNQ)2(DMF)2] (5) and [Cu(ClNQ)2] (6), where HClBrQ is 5-chloro-7-bromo-8-hydroxyquinoline, HBrQ is 7 ...
Martina Kepeňová, Martin Kello, Romana Smolková, Michal Goga, Richard Frenák, Ľudmila Tkáčiková, Miroslava Litecká, Jan Šubrt, Ivan Potočňák   +8 more
doaj   +1 more source

Determination of the “Privileged Structure” of 8‐Hydroxyquinoline

ChemPhysChem, 2021
AbstractAn accurate semi‐experimental equilibrium structure of 8‐hydroxyquinoline (8‐HQ) has been determined combining experiment and theory. The cm‐wave rotational spectrum of 8‐HQ was recorded in a pulsed supersonic jet using broadband dual‐path reflection and narrowband Fabry‐Perot‐type resonator Fourier‐transform microwave spectrometers.
McNaughton, Don, Wachsmuth, Dennis, Kraus, Peter, Herbers, Sven, Wang, Juan, Jens-Uwe Grabow   +5 more
openaire   +3 more sources

The mechanism of high-resolution STM/AFM imaging with functionalized tips [PDF]

, 2014
High resolution Atomic Force Microscopy (AFM) and Scanning Tunnelling Microscopy (STM) imaging with functionalized tips is well established, but a detailed understanding of the imaging mechanism is still missing.
Hapala, Prokop, Jelinek, Pavel, Kichin, Georgy, Tautz, F. Stefan, Temirov, Ruslan, Wagner, Christian   +5 more
core   +2 more sources

Synthesis and Characterization of Juglone‐Derived cu (II), Mn (II) and Zn (II) Complexes and Investigation of Their Cytotoxic Activities Against Lung and Colon Cancer Cells in Vitro and in Silico

Journal of Applied Toxicology, EarlyView.
ABSTRACT Three new Zn (II), Cu (II) and Mn (II) complexes have been synthesized from 5‐hydroxy‐1,4‐naphthoquinone (HNQ). Elemental analysis, magnetic susceptibility, UV–Vis, IR and Mass spectrometry have all been used to explore the structural characterization of these compounds.
Mustafa Öztatlıcı, Turan Birimoğlu, Semih Güler, Rukiye Betül Çolaksel, Mehmet Tahir Husunet, Mehmet Sönmez   +5 more
wiley   +1 more source