Results 81 to 90 of about 1,352 (137)

Validation of simplified uptake measures against dynamic Patlak K_i for quantification of lesional ⁸⁹Zr-Immuno-PET antibody uptake. [PDF]

Eur J Nucl Med Mol Imaging, 2023
Wijngaarden JE, Huisman MC, Jauw YWS, van Dongen GAMS, Greuter HNJM, Schuit RC, Cleveland M, Gootjes EC, Vugts DJ, Menke-van der Houven van Oordt CW, Boellaard R.   +10 more
europepmc   +1 more source

Advancing ⁸⁹Zr-immuno-PET in neuroscience with a bispecific anti-amyloid-beta monoclonal antibody - The choice of chelator is essential. [PDF]

Theranostics, 2022
Wuensche TE, Stergiou N, Mes I, Verlaan M, Schreurs M, Kooijman EJM, Janssen B, Windhorst AD, Jensen A, Asuni AA, Bang-Andersen B, Beaino W, Dongen GAMS, Vugts DJ.   +13 more
europepmc   +1 more source

The Research Progress of Monoclonal Antibody Labeled with 89Zr [PDF]

Zirconium-89 (89Zr) is a metallic positron-emitting radionuclide. The relatively long half-life and moderate energy making 89Zr especially suitable for the labeling of large biomolecules such as antibodies for radioimmuno-PET (positron emission ...
Fei DUAN, Hongyu LI, Zhanxiong XIAO
core   +1 more source

Biological testing of cetuximab labelled with 89Zr [PDF]

, 2023
Tato práce se zabývá testováním cetuximabu značeného pomocí 89Zr, ke značení byl použit chelátor desferrioxamin B squaramid (DFOSq). K přípravě konjugátu cetuximabu s DFOSq byly použity různé molární poměry. Stabilita konjugátů a konjugátů značených 89Zr
Lucie Dobiášová
core  

Mucin 18‐targeted humanized monoclonal antibody immune positron emission tomography imaging and patient‐derived tumor xenograft visualization

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In the context of precision diagnosis for various subtypes of melanoma, identifying biomarkers with clinical translational potential from a molecular standpoint is crucial for a more comprehensive characterization of the disease.
Qian Zhang, Haizhen Du, Xiuli Ma, Song Liu, Xiangxing Kong, Muye Hu, Jing Shi, Yanfang Tang, ShuHui Liu, Xun Meng, Qian Guo, Yan Kong, Jun Guo, Bin Lian, Zhi Yang, Hua Zhu   +15 more
doaj   +1 more source

Preparation of 89Zr by Cyclotron and its Purification and Labeling Methods [PDF]

In order to obtain high quality 89Zr nuclide for nuclear medicine imaging, 89Zr was produced by irradiating 89Y with HM-20S cyclotron. The nuclear reaction excitation function was calculated.
XU Zhiyu1, 2, YANG Dacan3, WANG Guixiang1, 2, CHENG Wanting3, WANG Fengqing3, MA Fuqiu1, 2
core   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

⁸⁹Zr-immuno-PET using the anti-LAG-3 tracer [⁸⁹Zr]Zr-BI 754111: demonstrating target specific binding in NSCLC and HNSCC. [PDF]

Eur J Nucl Med Mol Imaging, 2023
Miedema IHC, Huisman MC, Zwezerijnen GJC, Grempler R, Pitarch AP, Thiele A, Hesse R, Elgadi M, Peltzer A, Vugts DJ, van Dongen GAMS, de Gruijl TD, Menke-van der Houven van Oordt CW, Bahce I.   +13 more
europepmc   +1 more source

Evaluation of a 3-hydroxypyridin-2-one (2,3-HOPO) Based Macrocyclic Chelator for 89 Zr 4+ and Its Use for ImmunoPET Imaging of HER2 Positive Model of Ovarian Carcinoma in Mice [PDF]

, 2020
A novel octadentate 3-hydroxypyridin-2-one (2,3-HOPO) based di-macrocyclic ligand was evaluated for chelation of 89 Zr; subsequently, it was used as a bi-functional chelator for preparation of 89 Zr-labeled antibodies.
Alexander N Vanderbilt, Annie Ogasawara, Darpan N Pandya, Darren Magda, Herman S Gill, Jan Marik, Jan Marik, Jeff N Tinianow, Simon-P Williams, Sylvie L Pailloux, Thaddeus J Wadas   +10 more
core  

In Vivo Detection of Staphylococcus aureus Infections Using Radiolabeled Antibodies Specific for Bacterial Toxins

International Journal of Biomedical Imaging
Purpose. The Gram-positive Staphylococcus aureus bacterium is one of the leading causes of infection in humans. The lack of specific noninvasive techniques for diagnosis of staphylococcal infection together with the severity of its associated ...
María Isabel González, Mario González-Arjona, Lorena Cussó, Miguel Ángel Morcillo, John Jairo Aguilera-Correa, Jaime Esteban, Martha Kestler, Daniel Calle, Carlos Cerón, Marta Cortes-Canteli, Patricia Muñoz, Emilio Bouza, Manuel Desco, Beatriz Salinas   +13 more
doaj   +1 more source