Results 41 to 50 of about 39,694 (240)

New amino bisphosphonate compound for skeletal imaging: Comparison study with methylenediphosphonic acid (MDP) and (1-hydroxyethane-1,1-diyl) diphosphonic acid (HEDP)

Nukleonika, 2016
A novel bisphosphonate derivative (1-aminoethane-1,1-diyl)diphosphonic acid (AEDP) has been prepared and successfully labeled with 99mTc at high labeling yields.
Assaad Thaer
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

PERBANDINGAN POLA BIODISTRIBUSI 99mTc-CTMP dan 99mTc-MDP PADA HEWAN UJI SEBAGAI RADIOFARMAKA PENYIDIK TULANG [PDF]

, 2013
1,4,8,11-tetraaza cyclotetradecyl-1,4,8,11-tetramethylene phosponic acid (CTMP) sebagai senyawa baru untuk penyidik tulangtelah berhasil disintesis di PTNBR-BATAN Bandung yang kemudian ditandai denganradioisotop 99mTc.
Sugiharti, Rizky Juwita, ., Misyetti, Sumpena, Yana   +2 more
core   +2 more sources

Biodistribution of 99mTc-GE11 molecular probe and receptor imaging in nude mice bearing lung adenocarcinoma

Di-san junyi daxue xuebao, 2019
Objective To prepare a 99mTc-labled molecular probe (99mTc-GE11) targeting epidermal growth factor receptor (EGFR) on lung adenocarcinoma cells and evaluate its biodistribution and performance for EGFR imaging in nude mice bearing lung adenocarcinoma ...
TAN Zuwen, WU Mengxue, LI Yunjie, LEI Chengming, DENG Jie, DUAN Dong   +5 more
doaj   +1 more source

Prevalence of transthyretin cardiac amyloidosis in undifferentiated heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 1176-1182, April 2025.
Abstract Aims Transthyretin amyloid cardiomyopathy (ATTR‐CM) is an increasinglyrecognized cause of heart failure with preserved ejection fraction (HFpEF), which may be diagnosed non‐invasively using 99mTc 3,3‐diphosphono‐1,2‐propanodicarboxylic acid (DPD) scintigraphy‐based diagnostic criteria.
L. Healy, G. Giblin, A. Gray, N. Starr, L. Murphy, D. O'Sullivan, E. Kavanagh, C. Howley, C. Tracey, E. Morrin, A. McDaid, A. Clarke, J.O. O'Neill, E. Joyce, M. O'Connell, N. G. Mahon   +15 more
wiley   +1 more source

Synthesis and preclinical evaluation of novel 99mTc-labeled PSMA ligands for radioguided surgery of prostate cancer

EJNMMI Research, 2023
Background Radioguided surgery (RGS) has recently emerged as a valuable new tool in the management of recurrent prostate cancer (PCa). After preoperative injection of a 99mTc-labeled prostate-specific membrane antigen (PSMA) inhibitor, radioguided ...
Jan-Philip Kunert, Max Müller, Thomas Günther, León Stopper, Nicole Urtz-Urban, Roswitha Beck, Hans-Jürgen Wester   +6 more
doaj   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

CYCLOTRON-BASED ALTERNATIVE PRODUCTION OF 99mTc: INFN RESEARCH ACTIVITIES [PDF]

, 2013
Following preliminary feasibility studies started at Legnaro National Laboratories (LNL) in 2011, the Istituto Nazionale di Fisica Nucleare (INFN) research activities are underway since the kick-off of the IAEA CRP aimed at the alternative, accelerator-
Gini, L., Loriggiola, M., Simonelli, F., TAIBI, Angelo, UCCELLI, Licia, Uzunov, N., Groppi, F., Palmieri, V., Holzwarth, U., PUPILLO, Gaia, PASQUALI, Micol, Di Domencio, G., Esposito, J., BOSCHI, Alessandra, Melendez Alafort, L., Bello, M., Rossi, A., Manenti, Simone, Sartori, P., Rosato, A.   +19 more
core  

Novel 99mTc(III)-azide complexes [99mTc(N3)(CDO)(CDOH)2B-R] (CDOH2 = cyclohexanedione dioxime) as potential radiotracers for heart imaging [PDF]

, 2016
Introduction In this study, novel 99mTc(III)-azide complexes [99mTc(N3)(CDO)(CDOH)2B-R] (99mTc-ISboroxime-N3: R = IS; 99mTc-MPboroxime-N3: R = MP; 99mTc-PAboroxime-N3: R = PA; 99mTc-PYboroxime-N3: R = PY; and 99mTc-Uboroxime-N3: R = 5U) were evaluated as
Avcibasi U., Liu M., Zheng Y., Liu S.
core   +1 more source

Research on the Preparation of Irradiated-type 99Mo-99mTc Generator

Journal of Isotopes
Due to the excellent nuclear properties，99mTc has been used in the field of early diagnosis of tumor and nuclear medicine imaging. As the most widely applied radioisotope，it accounts for more than 70% of the market of total radioisotopes used in the ...
Siwei GU, Ning LUO, Bo LI, Qinzhi LI, Yingjiang HU, Yunming CHEN, Jinsong ZHANG   +6 more
doaj   +1 more source