Results 41 to 50 of about 26,991 (196)

Molecular theranostics: principles, challenges and controversies

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 156-164, March 2025.
Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley   +1 more source

Integrin αvβ3 Targeted Radiopharmaceutical 99mTc-RGD Combined with Anti-PD-L1 mAb to Enhance the Anti-tumor Effect in Tumor Immunotherapy

Xiehe Yixue Zazhi, 2023
Objective  To investigate the effect of 99mTc-labeled RGD peptide (99mTc-RGD) on regulating the tumor immune microenvironment and enhancing the anti-tumor effect of immunotherapy when combined with anti-programmed death-ligand 1 (PD-L1) antibody ...
WEN Xuejun, ZHOU Wuhao, GUO Zhide, ZHANG Xianzhong   +3 more
doaj   +1 more source

[Study on tumor affinity of technetium-99m-labeled radiopharmaceuticals. (2) 99mTc-Sn-diphosphonate (99mTc-EHDP), 99mTc-Sn-dimercaptosuccinic acid (99mTc-DMSA), and 99mTc-Sn-diethyl stilbestrol diphosphate (99mTc-DSDP)].

Radioisotopes, 1977
The authors have examined the tumor affinity of various 99mTc-labelled radiopharmaceuticals to Ehrlich's tumor for the purpose of delineating positively human malignant neoplasm. This paper includes biologic distributions of 99mTc-Sn-diphosphonate (99mTc-EHDP), 99mTc-Sn-dimercaptosuccinic acid (99mTc-DMSA) and 99mTc-Sn-diethyl stilbestrol diphosphate ...
K, Ito, S, Kobayashi, K, Hisada, N, Tonami, A, Ando   +4 more
openaire   +2 more sources

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

PEMBUATAN RADIONUKLIDA MOLIBDENUM-99 (99Mo) HASIL AKTIVASI NEUTRON DARI MOLIBDENUM ALAM UNTUK MEMPEROLEH TEKNESIUM-99m (99mTc)

Urania, 2016
ABSTRAK PEMBUATAN RADIONUKLIDA MOLIBDENUM-99 (99Mo) HASIL AKTIVASI NEUTRON DARI MOLIBDENUM ALAM UNTUK MEMPEROLEH TEKNESIUM-99m (99mTc). Pembatasan penggunaan uranium sebagai target untuk produksi 99mTc menyebabkan rumah sakit di Indonesia  kesulitan ...
Indra Saptiama, Herlina Herlina, Sriyono Sriyono, E. Sarmini, Abidin Abidin, Kadarisman Kadarisman   +5 more
doaj   +1 more source

Quantitative Dual‐Energy CT Perfusion Versus SPECT/CT V/Q Scintigraphy for Preoperative Lung Function Assessment: A Prospective Cohort Study

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Accurate preoperative physiological assessment is critical for high‐risk patients undergoing lung resection to predict postoperative lung function. This study compared quantitative dual‐energy CT (DECT) perfusion with SPECT/CT for lobar perfusion mapping in an at‐risk oncological cohort.
Jack Edward Liu, Kane Nicholls, Audree So, Siddharth M. Kulkarni, Anthony Tu Tran, Stephen A. Barnett, Amy Baker   +6 more
wiley   +1 more source

99mTc-radiopharmaceuticals: quality control of 99mTc-DPD

, 2022
9th Balkan congress of nuclear medicine, May 12-14, 2022., Vrdnik ...
Stanković, Dragana, Mirković, Marija D., Radović, Magdalena, Janković, Drina, Laban-Božić, Olivera, Matović, Milovan, Jeremić, Marija, Vranješ-Đurić, Sanja   +7 more
openaire   +1 more source

Dynamic SPECT Assessment of Hepatic Function in Patients With Liver Disease: A Systematic Review and Meta‐Analysis

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Dynamic Single Photon Emission Computed Tomography (dynSPECT) is an advanced functional imaging modality that enables estimation of temporal changes in radiopharmaceutical distribution and physiological function. While dynSPECT has been employed in several clinical applications, it has not been widely applied to liver imaging ...
Bader Aloufi, Roger Fulton, Kathy Willowson, Peter L. Kench   +3 more
wiley   +1 more source

The Evolution in Understanding the Physiological Causes of Dyspnoea in Large Hiatal Herniation: A Narrative Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background The symptomatology of large hiatus hernia (LHH) has been historically poorly understood, with cardiorespiratory symptoms caused by LHH being underappreciated by clinicians. This study reports on the mechanisms of dyspnoea in LHH through a historical review of symptoms and evolved physiological literature, discussing likely causation.
Arunan Mahendravarman, Fienne Cordeschi, Gregory Leighton Falk   +2 more
wiley   +1 more source

Technetium-99m-labeled stealth pH-sensitive liposomes: a new strategy to identify infection in experimental model

Brazilian Archives of Biology and Technology, 2007
The diagnosis of inflammatory and infectious processes is an important goal in medicine. The use of radiopharmaceuticals for identification of inflammation and infection foci has received considerable attention.
Vildete Aparecida Sousa Carmo, Mônica Cristina de Oliveira, Luciene das Graças Mota, Luís Paulo Freire, Raphael Ligório Benedito Ferreira, Valbert Nascimento Cardoso   +5 more
doaj   +1 more source