Results 61 to 70 of about 8,093,612 (203)

Plant organelle C‐to‐U RNA editing factors can operate successfully in yeast (Saccharomyces cerevisiae) as an easily amenable eukaryotic system for their functional analysis

open access: yesThe FEBS Journal, EarlyView.
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan   +4 more
wiley   +1 more source

Knowledge in the Investigation of A-to-I RNA Editing Signals [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2015
RNA editing is a post-transcriptional alteration of RNA sequences that is able to affect protein structure as well as RNA and protein expression. Adenosine-to-inosine (A-to-I) RNA editing is the most frequent and common post-transcriptional modification in human, where adenosine (A) deamination produces its conversion into inosine (I), which in turn is
Nigita G   +4 more
openaire   +3 more sources

Formal Component-Based Semantics [PDF]

open access: yes, 2011
One of the proposed solutions for improving the scalability of semantics of programming languages is Component-Based Semantics, introduced by Peter D. Mosses.
Bas Spitters   +15 more
core   +4 more sources

Optical Skyrmions Modulation Based on Polarization Helicity

open access: yesNanophotonics, Volume 15, Issue 9, 13 May 2026.
The polarization helicity represents the global twisted property of the polarization state distribution, it can be used to modulate the spin skyrmion texture in the tight focusing of the radially polarized vortex light. By adjusting the polarization helicity of incident field, the Néel‐Bloch‐Néel transition of the spin skyrmion texture can be realized,
Dong Xu   +5 more
wiley   +1 more source

Determinants of Specificity for the Trypanosoma brucei A to I tRNA Editing Deaminase [PDF]

open access: yes, 2008
Trypanosomatids are responsible for causing illness and death among millions of humans and animals worldwide. Two main genera of these unicellular flagellated parasites are Trypanosoma, which cause African sleeping sickness and Chagas disease, and ...
Tseng, Ashlie
core  

CRISPR Genome Editing and the Future of Leukaemia Immunotherapy

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Leukaemia presents ongoing therapeutic challenges due to relapse and toxicity associated with standard treatments. By enabling more targeted and safer therapies, CRISPR genome editing is emerging as a powerful tool to address these issues.
Dejin Rai, Umberto Terranova
wiley   +1 more source

The evolution and adaptation of A-to-I RNA editing

open access: yesPLOS Genetics, 2017
Adenosine-to-inosine (A-to-I) RNA editing is an important post-transcriptional modification that affects the information encoded from DNA to RNA to protein. RNA editing can generate a multitude of transcript isoforms and can potentially be used to optimize protein function in response to varying conditions.
Arielle L. Yablonovitch   +3 more
openaire   +4 more sources

Absolute quantification of fluorescent protein fusions by mass spectrometry

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Fusions with fluorescent proteins (FPs) play a pivotal role in experimental biology because of their sensitive and spatially precise visualization by spectroscopy. However, observed fluorescence is not always proportional to their molar concentration.
Anna Shevchenko   +8 more
wiley   +1 more source

Nurse-Led Intervention to Reduce Parental Anxiety and Child Pain During Non-Therapeutic Male Circumcision: A Randomized Trial

open access: yesSAGE Open Nursing
Introduction Non-therapeutic male circumcision is often performed in outpatient settings and has physical and emotional implications for children and families.
Lyudmyla Andrusenko-Kalchenko PhD   +5 more
doaj   +1 more source

Multi‐Omics Signatures of Organ Clocks in Biological Aging and Disease: A Conceptual Framework for Organ‐Specific Aging Clocks

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Organ‐specific aging clocks integrating genomics, epigenomics, transcriptomics, proteomics, and metabolomics offer a more accurate assessment of biological aging than single‐omics approaches. This review proposes a multi‐omics framework emphasizing tissue data, longitudinal study designs, and clinically meaningful training outcomes to advance the ...
Maria Vasileiou   +3 more
wiley   +1 more source

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