Results 61 to 70 of about 8,093,612 (203)
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan +4 more
wiley +1 more source
Knowledge in the Investigation of A-to-I RNA Editing Signals [PDF]
RNA editing is a post-transcriptional alteration of RNA sequences that is able to affect protein structure as well as RNA and protein expression. Adenosine-to-inosine (A-to-I) RNA editing is the most frequent and common post-transcriptional modification in human, where adenosine (A) deamination produces its conversion into inosine (I), which in turn is
Nigita G +4 more
openaire +3 more sources
Formal Component-Based Semantics [PDF]
One of the proposed solutions for improving the scalability of semantics of programming languages is Component-Based Semantics, introduced by Peter D. Mosses.
Bas Spitters +15 more
core +4 more sources
Optical Skyrmions Modulation Based on Polarization Helicity
The polarization helicity represents the global twisted property of the polarization state distribution, it can be used to modulate the spin skyrmion texture in the tight focusing of the radially polarized vortex light. By adjusting the polarization helicity of incident field, the Néel‐Bloch‐Néel transition of the spin skyrmion texture can be realized,
Dong Xu +5 more
wiley +1 more source
Determinants of Specificity for the Trypanosoma brucei A to I tRNA Editing Deaminase [PDF]
Trypanosomatids are responsible for causing illness and death among millions of humans and animals worldwide. Two main genera of these unicellular flagellated parasites are Trypanosoma, which cause African sleeping sickness and Chagas disease, and ...
Tseng, Ashlie
core
CRISPR Genome Editing and the Future of Leukaemia Immunotherapy
ABSTRACT Background and Aims Leukaemia presents ongoing therapeutic challenges due to relapse and toxicity associated with standard treatments. By enabling more targeted and safer therapies, CRISPR genome editing is emerging as a powerful tool to address these issues.
Dejin Rai, Umberto Terranova
wiley +1 more source
The evolution and adaptation of A-to-I RNA editing
Adenosine-to-inosine (A-to-I) RNA editing is an important post-transcriptional modification that affects the information encoded from DNA to RNA to protein. RNA editing can generate a multitude of transcript isoforms and can potentially be used to optimize protein function in response to varying conditions.
Arielle L. Yablonovitch +3 more
openaire +4 more sources
Absolute quantification of fluorescent protein fusions by mass spectrometry
Abstract Fusions with fluorescent proteins (FPs) play a pivotal role in experimental biology because of their sensitive and spatially precise visualization by spectroscopy. However, observed fluorescence is not always proportional to their molar concentration.
Anna Shevchenko +8 more
wiley +1 more source
Introduction Non-therapeutic male circumcision is often performed in outpatient settings and has physical and emotional implications for children and families.
Lyudmyla Andrusenko-Kalchenko PhD +5 more
doaj +1 more source
Organ‐specific aging clocks integrating genomics, epigenomics, transcriptomics, proteomics, and metabolomics offer a more accurate assessment of biological aging than single‐omics approaches. This review proposes a multi‐omics framework emphasizing tissue data, longitudinal study designs, and clinically meaningful training outcomes to advance the ...
Maria Vasileiou +3 more
wiley +1 more source

