Results 71 to 80 of about 8,093,612 (203)
An optimized methodology for whole genome sequencing of RNA respiratory viruses from nasopharyngeal aspirates [PDF]
, 2018 Over the last decade, the number of viral genome sequences deposited in available databases has grown exponentially. However, sequencing methodology vary widely and many published works have relied on viral enrichment by viral culture or nucleic acid ...
Goya, Stephanie +9 more
core +2 more sources
Insects, 2020 The most common type of RNA editing in metazoans is the deamination of adenosine into inosine (A-to-I) catalyzed by the adenosine deaminase acting on the RNA (ADAR) family of proteins.
Chongjun Ye +6 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT Aicardi–Goutières syndrome type 6 (AGS6) is a genetically determined autoinflammatory disorder, classically inherited in an autosomal recessive manner. We report a Czech child with a heterozygous ADAR1 NM_001111.5:c.3019G>A variant causing AGS6.
Katerina Turan +11 more
wiley +1 more source
UHECR narrow clustering correlating IceCube through-going muons
, 2016 The recent UHECR events by AUGER and the Telescope Array (TA) suggested that wide clusterings as the North and South, named Hot Spot, are related to near AGNs such as the one in M82 and Cen A.
Armiento, Daniele D +4 more
core +1 more source
FAFIT APPLICATION: SCRATCH WEB-BASED ENGLISH LEARNING INNOVATION
Tell-us JournalThis research aimed to develop a web-based Scratch listening learning media with the theme "My Family" for grade 9E students of SMPIT IMBOS Pringsewu. The research method employed a Research and Development (R&D) approach using the ADDIE model.
Fatma Yuniarti +2 more
doaj +1 more source
L-GIREMI uncovers RNA editing sites in long-read RNA-seq
Genome Biology, 2023 Although long-read RNA-seq is increasingly applied to characterize full-length transcripts it can also enable detection of nucleotide variants, such as genetic mutations or RNA editing sites, which is significantly under-explored.
Zhiheng Liu +7 more
doaj +1 more source
ADAR1 Controls Macrophage Scavenging and Lipid‐Buffering Programs in Metabolic Tissues
European Journal of Immunology, Volume 56, Issue 4, April 2026.ADAR1 expression increase during monocyte‐to‐macrophage differentiation via an alternative transcription start site. Isoform‐specific ADAR1 activity governs key macrophage functions, including efferocytosis, endocytosis, lipid metabolism, and proliferation.
Achilleas Fardellas +20 more
wiley +1 more source
Advances in A-to-I RNA editing in cancer
Molecular CancerRNA modifications are widespread throughout the mammalian transcriptome and play pivotal roles in regulating various cellular processes. These modifications are strongly linked to the development of many cancers. One of the most prevalent forms of RNA modifications in humans is adenosine-to-inosine (A-to-I) editing, catalyzed by the enzyme adenosine ...
Yi Zhang +9 more
openaire +3 more sources
Zinc Finger RNA-Binding Protein Zn72D Regulates ADAR-Mediated RNA Editing in Neurons
Cell Reports, 2020 Summary: Adenosine-to-inosine RNA editing, catalyzed by adenosine deaminase acting on RNA (ADAR) enzymes, alters RNA sequences from those encoded by DNA. These editing events are dynamically regulated, but few trans regulators of ADARs are known in vivo.
Anne L. Sapiro +8 more
doaj +1 more source
MedComm, Volume 7, Issue 4, April 2026.AAV6.2FF‐delivered CARTEL (mini‐dCas13X‐mediated A‐to‐I editor) introduces c.121A>G editing in β‐catenin RNA of alveolar type II cells, leading to sustained Wnt/β‐catenin activation, robust AT2 proliferation, significant attenuation of LPS‐induced acute lung injury, and no excess off‐target edits or fibrotic toxicity for 4 weeks.
Wenyi Liu +13 more
wiley +1 more source