Results 181 to 190 of about 584,058 (291)

Inhibiting ADAR1-Mediated Excessive Epigenetic A-to-I RNA Editing Improves the Immune Microenvironment and Increases Sensitivity to Immunotherapy in Lung Adenocarcinoma. [PDF]

MedComm (2020)
Wang S, Zheng S, Liu C, Zhang C, Wang X, Wang Z, Wang Y, Feng X, Xue Q, Sun N, He J.   +10 more
europepmc   +1 more source

Expanding the proteome: A-to-I RNA editing provides an adaptive advantage. [PDF]

Proc Natl Acad Sci U S A, 2023
Lewis ZA.
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Biological and prognostic relevance of A-to-I RNA editing across consensus molecular subtypes of colon cancer. [PDF]

Sci Rep
Monaco D, Traversa D, Mattioli E, Zito FA, Cristiani G, Buono F, Delcuratolo S, Guarino T, Pinto R, Lasorella A, Lacalamita R, Picardi E, Tommasi S, De Summa S.   +13 more
europepmc   +1 more source

Transcriptome analysis identification of A-to-I RNA editing in granulosa cells associated with PCOS. [PDF]

Front Endocrinol (Lausanne), 2023
Kong FS, Lu Z, Zhou Y, Lu Y, Ren CY, Jia R, Zeng B, Huang P, Wang J, Ma Y, Chen JH.   +10 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Editome profiling and cross-cohort validation reveal A-to-I RNA editing dysregulation in the hippocampus and prefrontal cortex of sepsis patients. [PDF]

Front Psychiatry
Shen J, Pan JQ, Yu TY, Liu LW, Li YN, Jin YY, Zhu M.   +6 more
europepmc   +1 more source

The occurrence, characteristics, and adaptation of A-to-I RNA editing in bacteria: A review. [PDF]

Front Microbiol, 2023
Liao W, Nie W, Ahmad I, Chen G, Zhu B.
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Identification of ADAR1i-124: The first effective A-to-I RNA editing inhibitor with promising cancer therapeutic potential. [PDF]

iScience
Minakuchi M, Zhang H, Cassel J, Shiromoto Y, Villanueva J, Skordalakes E, Salvino JM, Li Q, Nishikura K.   +8 more
europepmc   +1 more source