Results 71 to 80 of about 574,299 (199)

Conservation of A-to-I RNA editing in bowhead whale and pig

PLoS ONE, 2021
RNA editing is a post-transcriptional process in which nucleotide changes are introduced into an RNA sequence, many of which can contribute to proteomic sequence variation.
Knud Larsen, Mads Peter Heide-Jørgensen
doaj   +3 more sources

Developmental stage-specific A-to-I editing pattern in the postnatal pineal gland of pigs (Sus scrofa)

Journal of Animal Science and Biotechnology, 2020
Background RNA editing is a widespread post-transcriptional modification mechanism in mammalian genomes. Although many editing sites have been identified in domestic pigs (Sus scrofa), little is known about the characteristics and dynamic regulation of ...
Rong Zhou, Wenye Yao, Chundi Xie, Leixia Zhang, Yangli Pei, Hua Li, Zheng Feng, Yalan Yang, Kui Li   +8 more
doaj   +1 more source

Systematic identification of edited microRNAs in the human brain [PDF]

, 2012
Adenosine-to-inosine (A-to-I) editing modifies RNA transcripts from their genomic blueprint. A prerequisite for this process is a double-stranded RNA (dsRNA) structure.
Alon, Shahar, Church, George M., Eisenberg, Eli, Galeano, Federica, Gallo, Angela, Locatelli, Franco, Mor, Eyal, Shomron, Noam, Vigneault, Francois   +8 more
core   +1 more source

Recommendations for detection, validation, and evaluation of RNA editing events in cardiovascular and neurological/neurodegenerative diseases

Molecular Therapy: Nucleic Acids
RNA editing, a common and potentially highly functional form of RNA modification, encompasses two different RNA modifications, namely adenosine to inosine (A-to-I) and cytidine to uridine (C-to-U) editing. As inosines are interpreted as guanosines by the
Korina Karagianni, Alessia Bibi, Alisia Madé, Shubhra Acharya, Mikko Parkkonen, Teodora Barbalata, Prashant K. Srivastava, David de Gonzalo-Calvo, Constanza Emanueli, Fabio Martelli, Yvan Devaux, Dimitra Dafou, A. Yaël Nossent   +12 more
doaj   +1 more source

Reovirus infection induces transcriptome-wide unique A-to-I editing changes in the murine fibroblasts.

Virus Research
The conversion of Adenosine (A) to Inosine (I), by Adenosine Deaminases Acting on RNA or ADARs, is an essential post-transcriptional modification that contributes to proteome diversity and regulation in metazoans including humans.
Ayesha Tariq, Helen Piontkivska
doaj   +1 more source

Zalpha-domains: At the intersection between RNA editing and innate immunity [PDF]

, 2012
The involvement of A to I RNA editing in antiviral responses was first indicated by the observation of genomic hyper-mutation for several RNA viruses in the course of persistent infections.
Athanasiadis, Alekos
core   +1 more source

Genome-Wide Identification of RNA Editing Sites Affecting Intramuscular Fat in Pigs

Animals, 2020
Intramuscular fat (IMF) is essential for improving the palatability and flavor of meat, and it is strongly associated with human insulin resistance. RNA editing is a widespread regulating event in different tissues.
Ligang Wang, Jingna Li, Xinhua Hou, Hua Yan, Longchao Zhang, Xin Liu, Hongmei Gao, Fuping Zhao, Lixian Wang   +8 more
doaj   +1 more source

The conserved protein kinase-A target motif in synapsin of Drosophila is effectively modified by pre-mRNA editing. [PDF]

, 2011
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Buchner, Erich, Diegelmann, Sören, Hoppe, Jürgen, Nieratschker, Vanessa, Werner, Ursula, Zars, Troy   +5 more
core   +2 more sources

A-to-I mRNA Editing in a Ferric Siderophore Receptor Improves Competition for Iron in Xanthomonas oryzae pv. oryzicola

Microbiology Spectrum, 2021
Iron is an essential element for the growth and survival of pathogenic bacteria; however, it is not fully understood how bacteria sense and respond to iron deficiency or excess. In this study, we show that xfeA in Xanthomonas oryzae pv.
Wenhan Nie, Sai Wang, Jin Huang, Qin Xu, Peihong Wang, Yan Wu, Rui He, Ayizekeranmu Yiming, Jingling Liang, Iftikhar Ahmad, Luoyi Fu, Longbiao Guo, Junhua Yuan, Bo Zhu, Gongyou Chen   +14 more
doaj   +1 more source

A model for codon position bias in RNA editing [PDF]

, 2005
RNA editing can be crucial for the expression of genetic information via inserting, deleting, or substituting a few nucleotides at specific positions in an RNA sequence. Within coding regions in an RNA sequence, editing usually occurs with a certain bias
Bundschuh, Ralf, Liu, Tsunglin
core   +2 more sources