Results 51 to 60 of about 459,217 (330)

RNA-specific ribonucleotidyl transferases [PDF]

, 2007
RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent polymerases that add ribonucleotides to the 3'-ends of RNA molecules.
Keller, W., Martin, G., W. Keller, G. Martin   +3 more
core   +1 more source

Increased adenosine-to-inosine RNA editing in rheumatoid arthritis [PDF]

, 2020
Objective: Adenosine-to-inosine (A-to-I) RNA editing of Alu retroelements is a primate-specific mechanism mediated by adenosine deaminases acting on RNA (ADARs) that diversifies transcriptome by changing selected nucleotides in RNA molecules.
Stellos, K., Stamatelopoulos, K., Vlachogiannis, N. I., Silvestris, D. A., Tektonidou, M. G., Gatsiou, A., Gallo, A., Sfikakis, P. P.   +7 more
core   +1 more source

Massive A-to-I RNA editing is common across the Metazoa and correlates with dsRNA abundance

Genome Biology, 2017
Adenosine to inosine (A-to-I) RNA editing is a post-transcriptional modification catalyzed by the ADAR (adenosine deaminase that acts on RNA) enzymes, which are ubiquitously expressed among metazoans.
Hagit T. Porath, B. Knisbacher, E. Eisenberg, E. Levanon   +3 more
semanticscholar   +1 more source

A Role for A-to-I RNA Editing in Temperature Adaptation [PDF]

Physiology, 2012
A-to-I RNA editing can recode mRNAs, giving organisms the option to express diverse, functionally distinct protein isoforms. Here, we propose that RNA editing is inherently geared for temperature adaptation because it tends to recode to smaller, less stabilizing amino acids. Studies on how editing affects protein function support this idea.
Sandra C, Garrett, Joshua J C, Rosenthal
openaire   +2 more sources

RNA editing in interferonopathies

, 2021
The type I interferonopathies comprise a heterogenous group of monogenic diseases associated with a constitutive activation of type I interferon signaling.The elucidation of the genetic causes of this group of diseases revealed an alteration of nucleic ...
Michienzi A., Ciafre S. A., Galardi S., Frassinelli L.   +3 more
core   +1 more source

Changes in ADAR RNA editing patterns in CMV and ZIKV congenital infections

BMC Genomics, 2023
Background RNA editing is a process that increases transcriptome diversity, often through Adenosine Deaminases Acting on RNA (ADARs) that catalyze the deamination of adenosine to inosine.
Benjamin Wales-McGrath, Heather Mercer, Helen Piontkivska   +2 more
doaj   +1 more source

A-to-I RNA editing: current knowledge sources and computational approaches with special emphasis on non-coding RNA molecules

Frontiers in Bioengineering and Biotechnology, 2015
RNA editing is a dynamic mechanism for gene regulation attained through the alteration of the sequence of primary RNA transcripts. A-to-I (Adenosine-to-Inosine) RNA editing, which is catalyzed by members of the Adenosine Deaminase Acting on RNA (ADAR ...
Giovanni eNigita, Dario eVeneziano, Alfredo eFerro   +2 more
doaj   +1 more source

Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]

, 2010
For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Andrzej Dziembowski, Rafal Tomecki, Tomecki, Rafał, Dziembowski, Andrzej   +3 more
core   +1 more source

Table_7_Host A-to-I RNA editing signatures in intracellular bacterial and single-strand RNA viral infections.xlsx

, 2023
BackgroundMicrobial infection is accompanied by remodeling of the host transcriptome. Involvement of A-to-I RNA editing has been reported during viral infection but remains to be elucidated during intracellular bacterial infections.ResultsHerein we ...
Yu-Ning Li (12562204), Yan-Shuo Wen (15178717), Jian-Huan Chen (2833196), Zhi-Xin Wang (156984), Di Gao (501357), Yan-Shan Liu (11371530), Yun-Yun Jin (15178723), Zhi-Yuan Wei (10825668), Jia-Huan Li (11679433), Xu-Bin Pan (15178720), Shou-Yue Xia (12293144)   +10 more
core   +1 more source

Table_2_Host A-to-I RNA editing signatures in intracellular bacterial and single-strand RNA viral infections.xlsx

, 2023
BackgroundMicrobial infection is accompanied by remodeling of the host transcriptome. Involvement of A-to-I RNA editing has been reported during viral infection but remains to be elucidated during intracellular bacterial infections.ResultsHerein we ...
Yu-Ning Li (12562204), Yan-Shuo Wen (15178717), Jian-Huan Chen (2833196), Zhi-Xin Wang (156984), Di Gao (501357), Yan-Shan Liu (11371530), Yun-Yun Jin (15178723), Zhi-Yuan Wei (10825668), Jia-Huan Li (11679433), Xu-Bin Pan (15178720), Shou-Yue Xia (12293144)   +10 more
core   +1 more source