Results 51 to 60 of about 134,460,322 (302)

Image_3_Host A-to-I RNA editing signatures in intracellular bacterial and single-strand RNA viral infections.tif

, 2023
BackgroundMicrobial infection is accompanied by remodeling of the host transcriptome. Involvement of A-to-I RNA editing has been reported during viral infection but remains to be elucidated during intracellular bacterial infections.ResultsHerein we ...
Yu-Ning Li (12562204), Yan-Shuo Wen (15178717), Jian-Huan Chen (2833196), Zhi-Xin Wang (156984), Di Gao (501357), Yan-Shan Liu (11371530), Yun-Yun Jin (15178723), Zhi-Yuan Wei (10825668), Jia-Huan Li (11679433), Xu-Bin Pan (15178720), Shou-Yue Xia (12293144)   +10 more
core   +1 more source

Developmental stage-specific A-to-I editing pattern in the postnatal pineal gland of pigs (Sus scrofa)

Journal of Animal Science and Biotechnology, 2020
Background RNA editing is a widespread post-transcriptional modification mechanism in mammalian genomes. Although many editing sites have been identified in domestic pigs (Sus scrofa), little is known about the characteristics and dynamic regulation of ...
Rong Zhou, Wenye Yao, Chundi Xie, Leixia Zhang, Yangli Pei, Hua Li, Zheng Feng, Yalan Yang, Kui Li   +8 more
doaj   +1 more source

RESIC: A Tool for Comprehensive Adenosine to Inosine RNA Editing Site Identification and Classification

Frontiers in Genetics, 2021
Adenosine to inosine (A-to-I) RNA editing, the most prevalent type of RNA editing in metazoans, is carried out by adenosine deaminases (ADARs) in double-stranded RNA regions.
Dean Light, Roni Haas, Mahmoud Yazbak, Tal Elfand, Tal Blau, Ayelet T. Lamm   +5 more
doaj   +1 more source

Altered A-to-I RNA Editing in Human Embryogenesis

PLoS ONE, 2012
Post-transcriptional events play an important role in human development. The question arises as to whether Adenosine to Inosine RNA editing, catalyzed by the ADAR (Adenosine Deaminase acting on RNA) enzymes, differs in human embryogenesis and in adulthood.
Ronit Shtrichman, Igal Germanguz, Rachel Mandel, Anna Ziskind, Irit Nahor, Michal Safran, Sivan Osenberg, Ofra Sherf, Gideon Rechavi, Joseph Itskovitz-Eldor   +9 more
openaire   +4 more sources

Table_9_Host A-to-I RNA editing signatures in intracellular bacterial and single-strand RNA viral infections.xlsx

, 2023
BackgroundMicrobial infection is accompanied by remodeling of the host transcriptome. Involvement of A-to-I RNA editing has been reported during viral infection but remains to be elucidated during intracellular bacterial infections.ResultsHerein we ...
Yu-Ning Li (12562204), Yan-Shuo Wen (15178717), Jian-Huan Chen (2833196), Zhi-Xin Wang (156984), Di Gao (501357), Yan-Shan Liu (11371530), Yun-Yun Jin (15178723), Zhi-Yuan Wei (10825668), Jia-Huan Li (11679433), Xu-Bin Pan (15178720), Shou-Yue Xia (12293144)   +10 more
core   +1 more source

Recommendations for detection, validation, and evaluation of RNA editing events in cardiovascular and neurological/neurodegenerative diseases

Molecular Therapy: Nucleic Acids
RNA editing, a common and potentially highly functional form of RNA modification, encompasses two different RNA modifications, namely adenosine to inosine (A-to-I) and cytidine to uridine (C-to-U) editing. As inosines are interpreted as guanosines by the
Korina Karagianni, Alessia Bibi, Alisia Madé, Shubhra Acharya, Mikko Parkkonen, Teodora Barbalata, Prashant K. Srivastava, David de Gonzalo-Calvo, Constanza Emanueli, Fabio Martelli, Yvan Devaux, Dimitra Dafou, A. Yaël Nossent   +12 more
doaj   +1 more source

Image_1_Host A-to-I RNA editing signatures in intracellular bacterial and single-strand RNA viral infections.pdf

, 2023
BackgroundMicrobial infection is accompanied by remodeling of the host transcriptome. Involvement of A-to-I RNA editing has been reported during viral infection but remains to be elucidated during intracellular bacterial infections.ResultsHerein we ...
Yu-Ning Li (12562204), Yan-Shuo Wen (15178717), Jian-Huan Chen (2833196), Zhi-Xin Wang (156984), Di Gao (501357), Yan-Shan Liu (11371530), Yun-Yun Jin (15178723), Zhi-Yuan Wei (10825668), Jia-Huan Li (11679433), Xu-Bin Pan (15178720), Shou-Yue Xia (12293144)   +10 more
core   +1 more source

Reovirus infection induces transcriptome-wide unique A-to-I editing changes in the murine fibroblasts.

Virus Research
The conversion of Adenosine (A) to Inosine (I), by Adenosine Deaminases Acting on RNA or ADARs, is an essential post-transcriptional modification that contributes to proteome diversity and regulation in metazoans including humans.
Ayesha Tariq, Helen Piontkivska
doaj   +1 more source

A-to-I RNA editing and hematopoiesis

Experimental Hematology
Adenosine-to-inosine (A-to-I) RNA editing plays essential roles in modulating normal development and homeostasis. This process is catalyzed by adenosine deaminase acting on RNA (ADAR) family proteins. The most well-understood biological processes modulated by A-to-I editing are innate immunity and neurological development, attributed to ADAR1 and ADAR2,
Zhen, Liang, Carl R, Walkley, Jacki E, Heraud-Farlow   +2 more
openaire   +2 more sources

Table_3_Host A-to-I RNA editing signatures in intracellular bacterial and single-strand RNA viral infections.xlsx

, 2023
BackgroundMicrobial infection is accompanied by remodeling of the host transcriptome. Involvement of A-to-I RNA editing has been reported during viral infection but remains to be elucidated during intracellular bacterial infections.ResultsHerein we ...
Yu-Ning Li (12562204), Yan-Shuo Wen (15178717), Jian-Huan Chen (2833196), Zhi-Xin Wang (156984), Di Gao (501357), Yan-Shan Liu (11371530), Yun-Yun Jin (15178723), Zhi-Yuan Wei (10825668), Jia-Huan Li (11679433), Xu-Bin Pan (15178720), Shou-Yue Xia (12293144)   +10 more
core   +1 more source