Results 41 to 50 of about 134,460,322 (302)
RNA editing in interferonopathies
, 2021 The type I interferonopathies comprise a heterogenous group of monogenic diseases associated with a constitutive activation of type I interferon signaling.The elucidation of the genetic causes of this group of diseases revealed an alteration of nucleic ...
Michienzi A. +3 more
core +1 more source
Changes in ADAR RNA editing patterns in CMV and ZIKV congenital infections
BMC Genomics, 2023 Background RNA editing is a process that increases transcriptome diversity, often through Adenosine Deaminases Acting on RNA (ADARs) that catalyze the deamination of adenosine to inosine.
Benjamin Wales-McGrath +2 more
doaj +1 more source
Profiling A-to-I RNA editing during mouse somatic reprogramming at the single-cell level
Heliyon, 2023 Mouse somatic cells can be reprogrammed into induced pluripotent stem cells through a highly heterogeneous process regulated by numerous biological factors, including adenosine-to-inosine (A-to-I) RNA editing.
Tianhang Lv +3 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2015 RNA editing is a dynamic mechanism for gene regulation attained through the alteration of the sequence of primary RNA transcripts. A-to-I (Adenosine-to-Inosine) RNA editing, which is catalyzed by members of the Adenosine Deaminase Acting on RNA (ADAR ...
Giovanni eNigita +2 more
doaj +1 more source
Brain Epitranscriptomic Analysis Revealed Altered A-to-I RNA Editing in Septic Patients
Frontiers in Genetics, 2022 Recent studies suggest that RNA editing is associated with impaired brain function and neurological and psychiatric disorders. However, the role of A-to-I RNA editing during sepsis-associated encephalopathy (SAE) remains unclear.
Jing-Qian Zhang +22 more
doaj +1 more source
, 2023 BackgroundMicrobial infection is accompanied by remodeling of the host transcriptome. Involvement of A-to-I RNA editing has been reported during viral infection but remains to be elucidated during intracellular bacterial infections.ResultsHerein we ...
Yu-Ning Li (12562204) +10 more
core +1 more source
A hierarchy in clusters of cephalopod mRNA editing sites
Scientific Reports, 2022 RNA editing in the form of substituting adenine with inosine (A-to-I editing) is the most frequent type of RNA editing in many metazoan species. In most species, A-to-I editing sites tend to form clusters and editing at clustered sites depends on editing
Mikhail A. Moldovan +3 more
doaj +1 more source
, 2023 BackgroundMicrobial infection is accompanied by remodeling of the host transcriptome. Involvement of A-to-I RNA editing has been reported during viral infection but remains to be elucidated during intracellular bacterial infections.ResultsHerein we ...
Yu-Ning Li (12562204) +10 more
core +1 more source
Characterization of RNA Editome in the Mammary Gland of Yaks during the Lactation and Dry Periods
Animals, 2022 The mammary gland is a complicated organ comprising several types of cells, and it undergoes extensive morphogenetic and metabolic changes during the female reproductive cycle.
Xiaoyun Wu +7 more
doaj +1 more source
, 2023 BackgroundMicrobial infection is accompanied by remodeling of the host transcriptome. Involvement of A-to-I RNA editing has been reported during viral infection but remains to be elucidated during intracellular bacterial infections.ResultsHerein we ...
Yu-Ning Li (12562204) +10 more
core +1 more source