Results 21 to 30 of about 1,574,329 (197)
AMP Is an Adenosine A1 Receptor Agonist [PDF]
Journal of Biological Chemistry, 2012 Numerous receptors for ATP, ADP, and adenosine exist; however, it is currently unknown whether a receptor for the related nucleotide adenosine 5′-monophosphate (AMP) exists. Using a novel cell-based assay to visualize adenosine receptor activation in real time, we found that AMP and a non-hydrolyzable AMP analog (deoxyadenosine 5′-monophosphonate, ACP)
Joseph E, Rittiner +6 more
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Probe dependence of allosteric enhancers on the binding affinity of adenosine A1‐receptor agonists at rat and human A1‐receptors measured using NanoBRET [PDF]
, 2019 Background and Purpose: Adenosine is a local mediator that regulates a number of physiological and pathological processes via activation of adenosine A1‐receptors.
Samantha L. Cooper +11 more
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Journal of Pharmacological Sciences, 2023 This study investigated whether the repeated topical paeoniflorin inhibits postoperative pain in mice. An incision of the plantar skin and underlying muscle of the hind paw elicits acute postoperative pain.
Tsugunobu Andoh, Momoka Goto
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The glycoprotein nature of A1 adenosine receptors [PDF]
Biochemical and Biophysical Research Communications, 1986 A1 adenosine receptors from different tissues and species were photoaffinity labelled and then the carbohydrate content was examined by both enzymatic and chemical treatment. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of the labelled membrane receptors shows that neuraminidase treatment alters the electrophoretic mobility of the receptor
Klotz, Karl-Norbert, Lohse, M. J.
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Activity-dependent release of Adenosine: a critical re-evaluation of mechanism [PDF]
, 2008 Adenosine is perhaps the most important and universal modulator in the brain. The current consensus is that it is primarily produced in the extracellular space from the breakdown of previously released ATP.
Dale, Nicholas, Wall, Mark J.
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The Role of Adenosine Receptor Agonists in Regulation of Hematopoiesis
Molecules, 2011 The review summarizes data evaluating the role of adenosine receptor signaling in murine hematopoietic functions. The studies carried out utilized either non-selective activation of adenosine receptors induced by elevation of extracellular adenosine or ...
Michal Hofer +3 more
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The Journal of Headache and Pain, 2022 Background Adenosine is a purinergic signaling molecule with a wide range of physiological functions including anti- and pronociceptive properties. Adenosine receptors are expressed in the trigeminovascular system, and adenosine receptor antagonist ...
Janu Thuraiaiyah +3 more
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Adenosine A1 receptor activation mediates the developmental shift at layer 5 pyramidal cell synapses and is a determinant of mature synaptic strength [PDF]
, 2013 During the first postnatal month glutamatergic synapses between layer 5 pyramidal cells in the rodent neocortex switch from an immature state exhibiting high probability of neurotransmitter release, large unitary amplitude and synaptic depression to a ...
Richardson, Magnus J. E. +2 more
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Experimental and Molecular PathologyAdenosine serves as a critical homeostatic regulator, exerting influence over physiological and pathological conditions in the cardiovascular system.
Warisara Parichatikanond +3 more
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Impaired Inhibitory Function of Presynaptic A1-Adenosine Receptors in SHR Mesenteric Arteries
Journal of Pharmacological Sciences, 2013 In hypertension, vascular reactivity alterations have been attributed to numerous factors, including higher sympathetic innervation/adenosine. This study examined the modulation of adenosine receptors on vascular sympathetic nerves and their putative ...
Carolina Rocha-Pereira +5 more
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