Results 151 to 160 of about 303,232 (214)

Multiple Sclerosis and Viruses: « Liaisons Dangereuses »

Reviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina, Daniela Malakovska, Jolanta Kalnina, Ilva Trapina, Elina Leonova, Mohammed Habib, Susanne Schifmann, Jegors Paramonovs, Nikolajs Sjakste, Yegor Vassetzky, Emmanuel Drouet, Natalia Paramonova   +11 more
wiley   +1 more source

Histone Modifications at the Intersection of Aging, Neuroinflammation and Metabolism in Alzheimer's Disease

Aging Cell, Volume 25, Issue 11, November 2026.
This review examines how histone modifications integrate aging, metabolic dysfunction and neuroinflammation to shape persistent, cell‐type‐specific chromatin states in Alzheimer's disease. By distinguishing causal regulation from association through perturbation, persistence and reversibility, it highlights metabolic–epigenetic feedback loops and ...
Junyi Liang, Huawen Cao, Xiumin Ren, Nan Sha, Xueqing Han, Ling Jiang, Bin Liu, Weiming Zhao   +7 more
wiley   +1 more source

GABAergic Network Dysregulation in Alcohol Use Disorder: Receptor–Transporter Interactions Driving the Transition From Goal‐Directed to Compulsive Behaviour

Addiction Biology, Volume 31, Issue 11, November 2026.
Astrocytic GAT3 regulates ambient GABA levels in the globus pallidus externus (GPe). Reduced GAT3 function enhances extrasynaptic GABAergic signalling and disrupts subthalamic nucleus (STN) regulation and cortical signal fidelity.ABSTRACTAlcohol use disorder (AUD) is characterized by a shift from controlled, goal‐directed drinking to compulsive ...
Hannah Aranda, Nathan Jones, Humza Haroon, Doo‐Sup Choi   +3 more
wiley   +1 more source

Coupling between global brain blood oxygen level‐dependent activity and cerebrospinal fluid dynamics in young endurance athletes

Experimental Physiology, Volume 111, Issue 11, Page 5219-5235, 1 November 2026.
Abstract Cerebrospinal fluid (CSF) contributes to brain waste clearance through its coupling with cerebral haemodynamics. Aerobic exercise promotes brain health, but its influence on brain waste clearance remains unclear. This study examined the coupling between CSF and cerebral haemodynamics in endurance athletes. Fifteen young male endurance athletes
Daisuke Hoshi, Marina Fukuie, Ryota Asahara, Tsubasa Tomoto, David C. Zhu, Rong Zhang, Keigo Ohyama‐Byun, Seiji Maeda, Jun Sugawara, Takashi Tarumi   +9 more
wiley   +1 more source

Comorbid mechanisms of neuroinflammation and astrocytic ferroptosis in neurological disorders: A vicious cycle (Review). [PDF]

Biomed Rep
Zhang L, Wang D, Wang W, Chen J, Qian H, Ruan Y.   +5 more
europepmc   +1 more source

Mechanical Compression-Induced Peripheral Neuropathic Pain: From Astrocyte Mechanosensing and Phenotypic Reprogramming to CCL2-CCR2 Axis-Targeted Therapies. [PDF]

J Inflamm Res
Shen Y, He M, Wang B, Liu Z, Wu S, Chen LH, Ai K, Lv H, Sheng W, Zhang Z, Lv Z, Lv L.   +11 more
europepmc   +1 more source

Convergent Astrocytic Failure in Parkinson's Disease: A System-Level Model of Pathogenesis and Treatment. [PDF]

Mol Neurobiol
Abdelaziz AM, Fawzy MN, Shokr MM.
europepmc   +1 more source

A novel hydrogen persulfide donor HPD1 alleviated LPS-induced neuroinflammation by modulating glial polarization through TLR4-MAPK/NF-κB pathway. [PDF]

Redox Biol
Yan F, Tao S, Jiao Y, Kang T, Du S, Cheng Y, Huang Z, Feng P, Ke B.   +8 more
europepmc   +1 more source

Thirty years later: Revisiting the glial failure hypothesis as the homeostatic organizing principle of ischemic injury. [PDF]

J Cereb Blood Flow Metab
Herreras O, Canals S.
europepmc   +1 more source

Additive protection of transcranial direct current stimulation and mitochondrial transplantation on ischemic stroke via inducing A2 astrocytes. [PDF]

Front Mol Neurosci
Guo Y, Kang EM, Li M, Wang T, Sun Z, Wang Y, Jiang W, Li J.   +7 more
europepmc   +1 more source