Results 141 to 150 of about 379,625 (351)

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Annexin A1 in the nervous and ocular systems

Neural Regeneration Research
The therapeutic potential of Annexin A1, an important member of the Annexin superfamily, has become evident in results of experiments with multiple human systems and animal models.
Aijia Wang, Hong Zhang, Xing Li, Yin Zhao   +3 more
doaj   +1 more source

Dynamic allosteric networks drive adenosine A₁ receptor activation and G-protein coupling. [PDF]

Elife, 2023
Maria-Solano MA, Choi S.
europepmc   +1 more source

Adsorption-desorption noise can be used for improving selectivity

, 2002
Small chemical sensors are subjected to adsorption-desorption fluctuations which usually considered as noise contaminating useful signal. Based on temporal properties of this noise, it is shown that it can be made useful if proper processed.
Vidybida, Alexander K.
core   +1 more source

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

A1 adenosine receptor evoked Ca2+ signals in astrocytes

Current Directions in Biomedical Engineering
In addition to neurons, glial cells make up the nervous system. These glial cells are divided into macroglial cells - including astrocytes - and microglial cells.
Kienleitner Filip, Lenk Kerstin
doaj   +1 more source

Clues from a missense mutation of the adenosine A₁ receptor gene associated with early-onset Parkinson's disease. [PDF]

Neural Regen Res, 2023
Ferré S, Pardo L, Ciruela F.
europepmc   +1 more source

A clinicopathological analysis of forkhead box A1 (FOXA1) and estrogen receptor alpha expression in extramammary Paget's disease. [PDF]

, 2023
Chiho Sumitomo, Yohei Iwata, Masaru Arima, Kazumitsu Sugiura   +3 more
openalex   +1 more source

Directional Liquid Transport Enabled pH‐Responsive Hierarchical Composite for Enhanced Wound Healing

Advanced Healthcare Materials, EarlyView.
A hierarchical composite with a gradient architecture transitioning from hydrophobic to hydrophilic layers integrates diode‐like liquid transport, efficient water absorption, breathability, and mechanical robustness. This device enables a multifunctional therapeutic platform with pH‐responsive dual‐drug release, providing synergistic anti‐inflammatory ...
Baolin Wang, Li‐Fang Zhu, Yuna Lang, Siyi Zhang, Fei Chen, Ming‐Wei Chang   +5 more
wiley   +1 more source

Deciphering the Agonist Binding Mechanism to the Adenosine A1 Receptor. [PDF]

ACS Pharmacol Transl Sci, 2021
Deganutti G, Barkan K, Preti B, Leuenberger M, Wall M, Frenguelli BG, Lochner M, Ladds G, Reynolds CA.   +8 more
europepmc   +1 more source