Results 221 to 230 of about 379,625 (351)

The Signaling Pathways Involved in the Anticonvulsive Effects of the Adenosine A₁ Receptor. [PDF]

Int J Mol Sci, 2020
Spanoghe J, Larsen LE, Craey E, Manzella S, Van Dycke A, Boon P, Raedt R.   +6 more
europepmc   +1 more source

Transient receptor potential A1 (TRPA1) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Differential desensitization of A1 adenosine receptor-mediated inhibition of cardiac myocyte contractility and adenylate cyclase activity. Relation to the regulation of receptor affinity and density. [PDF]

, 1990
Bruce T. Liang, Lucy Donovan
openalex   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Ligand-Directed Labeling of the Adenosine A₁ Receptor in Living Cells. [PDF]

J Med Chem
Comeo E, Goulding J, Lin CY, Groenen M, Woolard J, Kindon ND, Harwood CR, Platt S, Briddon SJ, Kilpatrick LE, Scammells PJ, Hill SJ, Kellam B.   +12 more
europepmc   +1 more source

Podocyte Density and Albuminuria in Aging Diabetic Ins2± Mice with or Without Adenosine A1 Receptor Signaling. [PDF]

Int J Nephrol Renovasc Dis, 2020
Faulhaber-Walter R, Jiang L, Mizel D, Zerfas PM, Kopp JB, Schnermann JB, Chen L, Schiffer M.   +7 more
europepmc   +1 more source

Automated Benchmarking of Variable‐Property Soft Robotic Fingertips to Enable Task‐Optimized Sensor Selection

Advanced Science, EarlyView.
Sensorized fingertips are needed to unlock robotic dexterity, versatility, and diverse interactions. Here, 15 identically‐shaped robotic fingertips are benchmarked by a fully automated toolchange system, covering eight different materials and six broadly‐ranging sensing mechanisms.
David Hardman, Benhui Dai, Qinghua Guan, Antonia Georgopoulou, Fumiya Iida, Josie Hughes   +5 more
wiley   +1 more source

A pitvari A1 adenozin receptor által mediált direkt negatív inotróp hatáshoz tartozó receptor rezerv meghatározásának új módszere

, 2021
Tamás Erdei
openalex   +1 more source

109 COORDINATE REGULATION OF A1 AND A2 ADENOSINE RECEPTOR IN CULTURED NEUROBLASTOMA AND LYMPHOBLASTOID CELLS [PDF]

, 1988
Roberta M. Palmour, A.-M. Babey, Aaron Smith   +2 more
openalex   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source