Results 71 to 80 of about 2,894 (182)

Digital Biomarkers for Precision Early Detection of Lung Cancer: Integrating AI‐Driven Multi‐Omics Into Clinical Pathways

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley   +1 more source

Incidence Rate of Otitis Externa Episodes in Atopic Dogs Is Reduced by a Therapeutic Diet in a 6‐Month Randomised, Blinded, Controlled, Clinical Trial

Veterinary Dermatology, Volume 37, Issue 1, Page 89-102, February 2026.
ABSTRACT Background Recurrent otitis externa (OE) episodes commonly affect dogs with canine atopic dermatitis (cAD) despite ongoing cAD treatment. Objective To determine if a therapeutic diet with active ingredients targeting the skin barrier and allergy pathways reduces the incidence rate of OE.
Adrian Watson, Jeremy Laxalde, Franco Martini, Nina Fischer, Elisa Maina, Claude Favrot   +5 more
wiley   +1 more source

α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β1–42-stimulated murine astrocytes

Journal of Neuroinflammation, 2018
Background Neuroinflammation has an essential impact on the pathogenesis and progression of Alzheimer’s disease (AD). Mostly mediated by microglia and astrocytes, inflammatory processes lead to degeneration of neuronal cells.
Taraneh Ebrahimi, Marcus Rust, Sarah Nele Kaiser, Alexander Slowik, Cordian Beyer, Andreas Rembert Koczulla, Jörg B. Schulz, Pardes Habib, Jan Philipp Bach   +8 more
doaj   +1 more source

Development of a Four‐Language Questionnaire to Investigate Environmental Risk Factors for the Development of Canine Atopic Dermatitis and to Monitor Disease Course and Progression

Veterinary Dermatology, Volume 37, Issue 1, Page 34-44, February 2026.
Background: The chronic and multifactorial character of canine atopic dermatitis (cAD) often leads to poor disease control and treatment dissatisfaction. Environmental factors are likely to contribute to the disease development and may play a more important role than assumed previously.
Patricia Clara‐Maria Rhodius, Nina Fischer, Ana Rostaher, Franco Martini, Edwin Chapman, Sabrina Audergon, Stefan Hobi, Georg Lehner, Sylvie Wilhelm, Noëmi van Oordt, Claude Favrot, Malwina Kowalska   +11 more
wiley   +1 more source

Heterozygous Genotype rs17580 AT (PiS) in SERPINA1 is Associated with COPD Secondary to Biomass-Burning and Tobacco Smoking: A Case–Control and Populational Study

International Journal of COPD, 2020
Gloria Pérez-Rubio,1 Enrique Ambrocio-Ortiz,1 Luis A López-Flores,1 Ana I Juárez-Martín,2 Luis Octavio Jiménez-Valverde,1 Susana Zoreque-Cabrera,1 Gustavo Galicia-Negrete,1 María Elena Ramírez-Díaz ...
Pérez-Rubio G, Ambrocio-Ortiz E, López-Flores LA, Juárez-Martín AI, Jiménez-Valverde LO, Zoreque-Cabrera S, Galicia-Negrete G, Ramírez-Díaz ME, Cruz-Vicente F, Castillejos-López MJ, Salinas-Lara C, Hernández-Zenteno RJ, Ramírez-Venegas A, Falfán-Valencia R   +13 more
doaj  

Application of Salivary Alpha-1 Antitrypsin in the Diagnosis of Rheumatoid Arthritis: A Pilot Study

Medicina
Background and Objective: Rheumatoid arthritis (RA) is an autoimmune disease in which joints are gradually destroyed. Early diagnosis and treatment before joint deformation or destruction is important.
Sang Wan Chung, Seung-Jae Hong
doaj   +1 more source

Unusually difficult clinical presentation of an infant suffering from congenital cytomegalovirus (CMV) infection combined with alpha 1-antitrypsin (A1AT) deficiency [PDF]

, 2014
Ines Potočnjak, Goran Tešović, Andrea Tešija Kuna, Mario Štefanović, Orjena Žaja   +4 more
openalex   +1 more source

IgE-tailpiece associates with α-1-antitrypsin (A1AT) to protect IgE from proteolysis without compromising its ability to interact with FcεRI [PDF]

, 2016
P M Quinn, David W. Dunne, Shona C. Moore, Richard J. Pleass   +3 more
openalex   +1 more source

Additional file 5 of Label-free quantitative proteomics reveals aberrant expression levels of LRG, C9, FN, A1AT and AGP1 in the plasma of patients with colorectal cancer

, 2023
Chris Verathamjamras, Juthamard Chantaraamporn, Thiwaree Sornprachum, Photsathorn Mutapat, Daranee Chokchaichamnankit, Kanokwan Mingkwan, Virat Luevisadpibul, Chantragan Srisomsap, Somchai Chutipongtanate, Jisnuson Svasti, Voraratt Champattanachai   +10 more
openalex   +1 more source

ROC Analysis of Diagnostic Performance Utilizing Serum Antiproteases in Cancer Patients

The International Journal of Biological Markers, 1988
Assessment of the accuracy of diagnostic procedures is made independent of diagnostic criteria by means of a receiver-operating-characteristics (ROC) curve. We performed ROC analysis for the major serum antiproteases: alpha-1-antitrypsin (A1AT) and alpha-
J. Millán, A. Lorenzo, P. Gallurt, P. Rodriguez, J. Romero, J.J.B. López, A. Senra   +6 more
doaj   +1 more source