Results 101 to 110 of about 3,365 (168)
eLife, 2019 Many AAA+ ATPases form hexamers that unfold protein substrates by translocating them through their central pore. Multiple structures have shown how a helical assembly of subunits binds a single strand of substrate, and indicate that translocation results
Han Han +7 more
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Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle [PDF]
, 2018 Proteasomes occur in all three domains of life, and are the principal molecular machines for the regulated degradation of intracellular proteins. They play key roles in the maintenance of protein homeostasis, and control vital cellular processes.
Rudack, T. +13 more
core +1 more source
Data set for the manuscript "Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid ...
Wohlever, Matthew
core +1 more source
Characterization of the AAA-ATPase Drg1 and its activator Rlp24
, 2013 Die Assemblierung von eukaryontischen Ribosomen wird von Energie-verbrauchenden Enzymen angetrieben. Drg1 aus Saccharomyces cerevisiae ist eine essentielle AAA-ATPase die aus einer N-terminalen und zwei konservierten AAA Domänen besteht.
Loibl, Mathias
core +1 more source
Molecular snapshots of the Pex1/6 AAA + complex in action [PDF]
, 2015 The peroxisomal proteins Pex1 and Pex6 form a heterohexameric type II AAA+ ATPase complex, which fuels essential protein transport across peroxisomal membranes. Mutations in either ATPase in humans can lead to severe peroxisomal disorders and early death.
Wendler, Petra +5 more
core +1 more source
Functional analysis of the Arabidopsis At1g64110 AAA+ATPase
, 2019 Das Gen At1g64110 aus Arabidopsis thaliana stammt aus einer kleinen Gruppe von Genen die für AAA+ATPasen codieren zu denen auch At5g52882 und At4g28000 zählen.
Kramberger-Kaplan, Lukas
core
Structure and function of the membrane deformation AAA ATPase Vps4
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2012 The ATPase Vps4 belongs to the type-I AAA family of proteins. Vps4 functions together with a group of proteins referred to as ESCRTs in membrane deformation and fission events. These cellular functions include vesicle formation at the endosome, cytokinesis and viral budding.
Hill, Christopher P., Babst, Markus
openaire +2 more sources
Subunit composition, assembly and regulation of human TIP48 and TIP49 complexes [PDF]
, 2009 The two closely related eukaryotic AAA+ proteins, TIP48 and TIP49, are essential components of large multi-protein complexes that are involved in diverse cellular processes.
Niewiarowski, A.
core
, 2002 Characterization of mammalian NSF (G274E) and Drosophila NSF (comatose) mutants revealed an evolutionarily conserved NSF activity distinct from ATPase-dependent SNARE disassembly that was essential for Golgi membrane fusion.
Yuval Sagiv +15 more
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The AAA-ATPase p97 facilitates degradation of apolipoprotein B by the ubiquitin-proteasome pathways⃞
Journal of Lipid Research, 2008 The ATPase associated with various cellular activities (AAA-ATPase) p97 (p97) has been implicated in the retrotranslocation of target proteins for delivery to the cytosolic proteasome during endoplasmic reticulum-associated degradation (ERAD ...
Eric A. Fisher +3 more
doaj +1 more source