Results 231 to 240 of about 144,727 (384)
1308. Marker Rescue of Adeno-Associated Virus (AAV) Capsid Mutants: A Novel Approach for Chimeric AAV Production [PDF]
, 2002 openalex +1 more source
An Amygdala‐hippocampus Circuit for Endocannabinoid Modulation of Anxiety Avoidance
Advanced Science, EarlyView.This study employs three synapse‐specific endocannabinoids (eCB) probes to monitor dynamic eCB release, activate CB1Rs and knockdown 2‐AG biosynthesis enzymes in glutamatergic anterior basolateral amygdala ‐ ventral hippocampus (aBLA–vHPC) circuit. At aBLA–vHPC circuits, activation of CB1Rs reduce anxiety avoidance, and knockdown of eCB biosynthesis ...
Bao Xue +9 more
wiley +1 more source
Circulating miRNAs as potential non-invasive biomarkers for ANCA-associated glomerulonephritis. [PDF]
Front ImmunolBošnjak M +5 more
europepmc +1 more source
565. Double Stranded AAV Offers Far More Than Doubled Gene Transfer [PDF]
, 2002 openalex +1 more source
A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness
Advanced Science, EarlyView.This study identifies a sub‐circuit within the circadian pacemaker suprachiasmatic nucleus (SCN) that promotes arousal. This sub‐circuit is labeled by the clock output molecule mWAKE, which suppresses its excitability in a time‐dependent manner. mWAKE‐expressing cells in the SCN (SCNmWAKE cells) project to the subparaventricular zone (SPZ) to mediate ...
Qiang Liu +6 more
wiley +1 more source
1310. AAV Vectors Based on Novel Serotypes for Muscle and Liver Directed Gene Transfer [PDF]
, 2002 openalex +1 more source
Advanced Science, EarlyView.βFaar selectively targets and inhibits the GTPase activity of the RAB18 protein, thereby reducing LD volume. Conversely, βFaar promotes nuclear translocation of the transcription factor IRF4 in inguinal white adipose tissue (iWAT), facilitating the browning of white adipose tissue and attenuating body fat accumulation.
Yue Yang +13 more
wiley +1 more source
1043. AAV Mediated Enzyme Replacement Therapy for Fabry Disease: Echocardiographic Evaluation of Gene Therapy of Fabry Mice [PDF]
, 2002 openalex +1 more source
YTHDC1 Is Essential for Postnatal Liver Development and Homeostasis
Advanced Science, EarlyView.This study identifies YTHDC1 as a key regulator of postnatal liver development and disease. Hepatocyte‐specific deletion of Ythdc1 impairs hepatocyte maturation, causing liver injury, contributing to nonalcoholic steatohepatitis and hepatocellular carcinoma.
Xinzhi Li +8 more
wiley +1 more source