Results 241 to 250 of about 144,727 (384)

1374. Treatment of β-Thalassemia in the Mouse by Regulated Expression of AAV Encoded Erythropoietin [PDF]

, 2002

openalex   +1 more source

Endothelial‐Derived CCL7 Promotes Macrophage Polarization and Aggravates Septic Acute Lung Injury via CCR1‐Mediated STAT1 Succinylation

Advanced Science, EarlyView.
During sepsis, pulmonary vascular endothelial cells secrete chemokine CCL7, which plays a pivotal role in facilitating the infiltration of C‐C motif chemokine receptor 1‐positive (CCR1+) macrophages into lung tissue. Activation of the CCL7–CCR1 axis enhances the succinylation of STAT1 mediated by KAT2A, thereby driving metabolic reprogramming and ...
Xue Li, Yuqin Long, Yunxi Zhu, Jiahui Gu, Ping Zhou, Changhong Miao   +5 more
wiley   +1 more source

Replication competent helper functions for recombinant AAV vector generation

, 2002
Lei Cao, M J During, Weidong Xiao
openalex   +1 more source

597. Hybrid Ad/AAV Vectors for Site-Specific Integration of Large DNA Fragments into the Human Genome [PDF]

, 2002

openalex   +1 more source

Topics in AAV integration come front and center at ASGCT AAV Integration Roundtable

Molecular Therapy, 2021
Denise E. Sabatino, Douglas M McCarty
openaire   +3 more sources

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models

Advanced Science, EarlyView.
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang, Fang Li, Jiao Liu, Shu‐Ang Li, Dan‐Hua Liu, Zhuanbin Wu, Pei‐Pei Liu, Wenju Liu, Bin Zhou, Cizhong Jiang, Haibing Zhang, Ying Yu, Jian‐Sheng Kang   +12 more
wiley   +1 more source

Profiling the impact of different tau species on glial cell biology. [PDF]

Front Cell Dev Biol
Arribas Gomez I, Yan Y, Lilley MT, Chen Y, Daughrity LM, Moreno Arnas A, Shi J, Kachergus JM, Thompson EA, Jansen-West K, Cook CN.   +10 more
europepmc   +1 more source

584. Improvement of Transduction Efficiency from Split AAV Vectors [PDF]

, 2002

openalex   +1 more source

A multifunctional AAV–CRISPR–Cas9 and its host response

Nature Methods, 2016
W. Chew, Mohammadsharif Tabebordbar, Jason K. W. Cheng, P. Mali, Elizabeth Y. Wu, Alex H. M. Ng, Kexian Zhu, A. Wagers, G. Church   +8 more
semanticscholar   +1 more source

ALKBH5‐Mediated M6A Demethylation of G3BP1 Attenuates Ferroptosis Via Cytoplasmic Retention of YBX1/p53 in Diabetic Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li, Wei Li, Yan Leng, Heng Xu, Zhongyuan Xia, Yao Wang   +5 more
wiley   +1 more source