Results 31 to 40 of about 507,524 (341)

Relationship between conformation shift and disease related variation sites in ATP-binding cassette transporter proteins

Biophysics and Physicobiology, 2019
Transport of small molecules across the cell membrane is a crucial biological mechanism for the maintenance of the cell activity. ABC transporter family is a huge group in the transporter membrane proteins and actively transports the substrates using the
Mika Sakamoto, Hirofumi Suzuki, Kei Yura
doaj   +1 more source

Karanjin interferes with ABCB1, ABCC1, and ABCG2

Journal of Pharmacy & Pharmaceutical Sciences, 2014
PURPOSE: The prominent ATP-binding cassette (ABC) transporters ABCB1, ABCC1, and ABCG2 are involved in substance transport across physiological barriers and therefore in drug absorption, distribution, and elimination.
Martin Michaelis, Florian Rothweiler, Thomas Nerreter, Mohsen Sharifi, Taravat Ghafourian, Jindrich Cinatl   +5 more
doaj   +1 more source

Controlled functional expression of the bacteriocins pediocin PA-1 and bactofencin A in Escherichia coli [PDF]

, 2017
peer-reviewedThe bacteriocins bactofencin A (class IId) and pediocin PA-1 (class IIa) are encoded by operons with a similarly clustered gene organization including a structural peptide, an immunity protein, an ABC transporter and accessory bacteriocin ...
Cotter, Paul D., Hill, Colin, Mesa-Pereira, Beatriz, O’Connor, Paula M., Rea, Mary, Ross, R Paul   +5 more
core   +3 more sources

Antibiotic Resistance Mediated by the MacB ABC Transporter Family: A Structural and Functional Perspective

Frontiers in Microbiology, 2018
The MacB ABC transporter forms a tripartite efflux pump with the MacA adaptor protein and TolC outer membrane exit duct to expel antibiotics and export virulence factors from Gram-negative bacteria.
N. Greene, E. Kaplan, A. Crow, V. Koronakis   +3 more
semanticscholar   +1 more source

Engineering endogenous ABC transporter with improving ATP supply and membrane flexibility enhances the secretion of β-carotene in Saccharomyces cerevisiae

Biotechnology for Biofuels, 2020
Background Product toxicity is one of the bottlenecks for microbial production of biofuels, and transporter-mediated biofuel secretion offers a promising strategy to solve this problem.
Xiao Bu, Jing-Yuan Lin, Jing Cheng, Dong Yang, Chang-Qing Duan, M. Koffas, G. Yan   +6 more
semanticscholar   +1 more source

ABCC6 Knockdown Fuels Cell Proliferation by Regulating PPARα in Hepatocellular Carcinoma

Frontiers in Oncology, 2022
The ATP binding cassette (ABC) transporter family is ubiquitous in eukaryotes, specifically in vertebrates, and plays a crucial role in energy homeostasis, cell signaling, and drug resistance.
Zhicong Zhao, Zhicong Zhao, Zhenjun Zhao, Jianye Wang, Jianye Wang, He Zhang, He Zhang, Zhifeng Xi, Qiang Xia, Qiang Xia, Qiang Xia   +10 more
doaj   +1 more source

Diversity and evolution of ABC proteins in mycorrhiza-forming fungi [PDF]

, 2015
Background: Transporter proteins are predicted to have an important role in the mycorrhizal symbiosis, due to the fact that this type of an interaction between plants and fungi requires a continuous nutrient and signalling exchange.
Asiegbu, Fred O., Kohler, Annegret, Kovalchuk, Andriy, Martin, Francis   +3 more
core   +3 more sources

The human ABC transporter pseudogene family: Evidence for transcription and gene-pseudogene interference

BMC Genomics, 2008
Background Pseudogenes are an integral component of the human genome. Little attention, however, has so far been paid to the phenomenon that some pseudogenes are transcriptionally active.
Haug Kari, Kaminski Ellen, Wenzel Jürgen J, Hellum Marit, Piehler Armin P, Kierulf Peter, Kaminski Wolfgang E   +6 more
doaj   +1 more source

Structural basis for the mechanism of ABC transporters. [PDF]

, 2015
The ATP-binding cassette (ABC) transporters are primary transporters that couple the energy stored in adenosine triphosphate (ATP) to the movement of molecules across the membrane.
Beis, K
core   +1 more source

A critical view on abc transporters and their interacting partners in auxin transport [PDF]

, 2017
Different subclasses of ATP-binding cassette (ABC) transporters have been implicated in the transport of native variants of the phytohormone auxin.
Aryal, Bibek, Di Donato, Martin, Geisler, Markus, Hao, Pengchao   +3 more
core   +1 more source