Results 11 to 20 of about 110,036 (294)
ABC transporters: the power to change [PDF]
Nature Reviews Molecular Cell Biology, 2009 ATP-binding cassette (ABC) transporters constitute a ubiquitous superfamily of integral membrane proteins that are responsible for the ATP-powered translocation of many substrates across membranes.
Johnson, Eric +2 more
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The Arabidopsis Book, 2011 ABC transporters constitute one of the largest protein families found in all living organisms. ABC transporters are driven by ATP hydrolysis and can act as exporters as well as importers. The plant genome encodes for more than 100 ABC transporters, largely exceeding that of other organisms.
Joohyun Kang +6 more
openaire +3 more sources
Sensitive and specific fluorescent probes for functional analysis of the three major types of mammalian ABC transporters. [PDF]
PLoS ONE, 2011 An underlying mechanism for multi drug resistance (MDR) is up-regulation of the transmembrane ATP-binding cassette (ABC) transporter proteins. ABC transporters also determine the general fate and effect of pharmaceutical agents in the body.
Irina V Lebedeva +2 more
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The impact of ATP-binding cassette transporters on metabolic diseases
Nutrition & Metabolism, 2020 Currently, many people worldwide suffer from metabolic diseases caused by heredity and external factors, such as diet. One of the symptoms of metabolic diseases is abnormal lipid metabolism.
Zixiang Ye, Yifei Lu, Tao Wu
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Microorganisms, 2021 ATP-binding cassette (ABC) transporters are usually involved in the translocation of their cognate substrates, which is driven by ATP hydrolysis. Typically, these transporters are required for the import or export of a wide range of substrates such as ...
Jeanine Rismondo, Lisa Maria Schulz
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Aberrant DNA Methylation of ABC Transporters in Cancer
Cells, 2020 ATP-binding cassette (ABC) transporters play a crucial role in multidrug resistance (MDR) of cancers. They function as efflux pumps, resulting in limited effectiveness or even failure of therapy.
Katja Zappe, Margit Cichna-Markl
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Current Issues in Molecular Biology, 2022 ATP-binding cassette (ABC) transporters play an important role in driving the exchange of multiple molecules across cell membranes. The plant ABC transporter family is among the largest protein families, and recent progress has advanced our understanding
Xiaoping Gong, Shanhong Wang
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Cells, 2021 The ATP-binding cassette (ABC) transporter superfamily consists of several proteins with a wide repertoire of functions. Under physiological conditions, ABC transporters are involved in cellular trafficking of hormones, lipids, ions, xenobiotics, and ...
Massimo Serra +6 more
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Plants, 2020 The multi-antimicrobial extrusion (MATE), ATP-binding cassette (ABC), and major facilitator superfamily (MFS) are the main plant transporters families, playing an essential role in the membrane-trafficking network and plant-defense mechanism.
Maria H. M. Julião +3 more
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Regulation of ABC Drug Efflux Transporters in Human T-Cells Exposed to an HIV Pseudotype
Frontiers in Pharmacology, 2021 ATP-binding cassette (ABC) drug efflux transporters could contribute to low intracellular concentrations of antiretroviral drugs in HIV-1 cell reservoirs and sanctuary sites.
Sana-Kay Whyte-Allman +2 more
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